Inhibitory effect of Morinda citrifolia L. on lipoprotein lipase activity.
Efficacy of Morinda citrifolia L. leaf (MLE) and fruit extracts (MFE) in inhibiting lipoprotein lipase (LPL) was determined in vitro. The result of the study showed that the highest inhibition on the LPL activity was exhibited by MLE (66%± 2.1%), which is significantly higher than that demonstrated...
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| Format: | Article |
| Language: | English English |
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Wiley-Blackwell
2008
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| Online Access: | http://psasir.upm.edu.my/id/eprint/15235/ http://psasir.upm.edu.my/id/eprint/15235/1/Inhibitory%20effect%20of%20Morinda%20citrifolia%20L.pdf |
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| author | Pak Dek, Mohd Sabri Abdul Hamid, Azizah Osman, Azizah Soh, C.S |
| author_facet | Pak Dek, Mohd Sabri Abdul Hamid, Azizah Osman, Azizah Soh, C.S |
| author_sort | Pak Dek, Mohd Sabri |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Efficacy of Morinda citrifolia L. leaf (MLE) and fruit extracts (MFE) in inhibiting lipoprotein lipase (LPL) was determined in vitro. The result of the study showed that the highest inhibition on the LPL activity was exhibited by MLE (66%± 2.1%), which is significantly higher than that demonstrated by MFE (54.5%± 2.5%), green tea extract (GTE) (54.5%± 2.6%), and catechin (43.6%± 6.1%). Percent of LPL inhibition increase with concentration of the extracts. Quantitative analysis of the extracts revealed the presence of high levels of (+)−catechin at 63.5 ± 17 and 53.7 ± 5.7 mg/g in MLE and MFE, respectively, although not as high as that found in GTE (530.6 ± 42 mg/g). Appreciable amount of epicatechin was found in all extracts tested, while rutin was only found in MLE and MFE. The study suggested that both leaf and fruit of M. citrifolia may be used as antiobesity agents in body weight management. |
| first_indexed | 2025-11-15T08:02:01Z |
| format | Article |
| id | upm-15235 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T08:02:01Z |
| publishDate | 2008 |
| publisher | Wiley-Blackwell |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-152352015-10-29T01:45:44Z http://psasir.upm.edu.my/id/eprint/15235/ Inhibitory effect of Morinda citrifolia L. on lipoprotein lipase activity. Pak Dek, Mohd Sabri Abdul Hamid, Azizah Osman, Azizah Soh, C.S Efficacy of Morinda citrifolia L. leaf (MLE) and fruit extracts (MFE) in inhibiting lipoprotein lipase (LPL) was determined in vitro. The result of the study showed that the highest inhibition on the LPL activity was exhibited by MLE (66%± 2.1%), which is significantly higher than that demonstrated by MFE (54.5%± 2.5%), green tea extract (GTE) (54.5%± 2.6%), and catechin (43.6%± 6.1%). Percent of LPL inhibition increase with concentration of the extracts. Quantitative analysis of the extracts revealed the presence of high levels of (+)−catechin at 63.5 ± 17 and 53.7 ± 5.7 mg/g in MLE and MFE, respectively, although not as high as that found in GTE (530.6 ± 42 mg/g). Appreciable amount of epicatechin was found in all extracts tested, while rutin was only found in MLE and MFE. The study suggested that both leaf and fruit of M. citrifolia may be used as antiobesity agents in body weight management. Wiley-Blackwell 2008 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/15235/1/Inhibitory%20effect%20of%20Morinda%20citrifolia%20L.pdf Pak Dek, Mohd Sabri and Abdul Hamid, Azizah and Osman, Azizah and Soh, C.S (2008) Inhibitory effect of Morinda citrifolia L. on lipoprotein lipase activity. Journal of Food Science, 73 (8). C595-C598. ISSN 0022-1147 10.1111/j.1750-3841.2008.00929.x English |
| spellingShingle | Pak Dek, Mohd Sabri Abdul Hamid, Azizah Osman, Azizah Soh, C.S Inhibitory effect of Morinda citrifolia L. on lipoprotein lipase activity. |
| title | Inhibitory effect of Morinda citrifolia L. on lipoprotein lipase activity. |
| title_full | Inhibitory effect of Morinda citrifolia L. on lipoprotein lipase activity. |
| title_fullStr | Inhibitory effect of Morinda citrifolia L. on lipoprotein lipase activity. |
| title_full_unstemmed | Inhibitory effect of Morinda citrifolia L. on lipoprotein lipase activity. |
| title_short | Inhibitory effect of Morinda citrifolia L. on lipoprotein lipase activity. |
| title_sort | inhibitory effect of morinda citrifolia l. on lipoprotein lipase activity. |
| url | http://psasir.upm.edu.my/id/eprint/15235/ http://psasir.upm.edu.my/id/eprint/15235/ http://psasir.upm.edu.my/id/eprint/15235/1/Inhibitory%20effect%20of%20Morinda%20citrifolia%20L.pdf |