Immunostimulatory effects of arginine in broiler chickens challenged with vaccine strain of infectious bursal disease virus
Infectious Bursal Disease (IBD) continues to pose potential threat to poultry industry all over the world. The disease can spell disaster not only through its infection but also by break of immunity in chickens vaccinated for other diseases. On the other hand, arginine (Arg), a ubiquitous, semi-esse...
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| Format: | Article |
| Language: | English |
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Medwell Journals
2010
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| Online Access: | http://psasir.upm.edu.my/id/eprint/15102/ http://psasir.upm.edu.my/id/eprint/15102/1/Immunostimulatory%20effects%20of%20arginine%20in%20broiler%20chickens%20challenged%20with%20vaccine%20strain%20of%20infectious%20bursal%20disease%20virus.pdf |
| _version_ | 1848842582976626688 |
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| author | Emadi, Mozhdeh Jahanshiri, Fatemeh Jalilian, Farid Azizi Kaveh, Kamran Bejo, Mohd Hair Ideris, Aini Assumaidaee, A. A. Alimon, Abdul Razak |
| author_facet | Emadi, Mozhdeh Jahanshiri, Fatemeh Jalilian, Farid Azizi Kaveh, Kamran Bejo, Mohd Hair Ideris, Aini Assumaidaee, A. A. Alimon, Abdul Razak |
| author_sort | Emadi, Mozhdeh |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Infectious Bursal Disease (IBD) continues to pose potential threat to poultry industry all over the world. The disease can spell disaster not only through its infection but also by break of immunity in chickens vaccinated for other diseases. On the other hand, arginine (Arg), a ubiquitous, semi-essential amino acid has emerged as an imunostimulant from variety of human and animal studies. In the present study, we demonstrate the stimulatory effects of Arg on systemic immune response in chickens challenged by orally administration of intermediate plus strain of IBD virus at 28 days of age. A corn-soybean meal based diet containing different levels of Arg (0, 0.67, 1.37, 2.07 and 2.77) for the starter, (0, 0.53, 1.1, 1.68 and 2.25) for the grower and (0, 0.52, 1.04, 1.56 and 2.08) for the finisher was used. In a completely randomized design with five treatments of five replicates each and 10 chickens per replicate, 250 Cobb500 male broiler chickens from 0-49 days of age were used. To measure the innate, cellular and humoral immunity indicators (interferon-α, interferon-γ, immunoglobulin G) at 27, 35, 42 and 49 days of age, serum samples from each replicate of treatments were collected and subjected to ELISA. The result showed that Arg supplementation in the chickens basal diets significantly increased the serum levels of interferon-α, interferon-γ, immunoglobulin G at 35, 42 and 49 days of age (p<0.05). The different levels of Arg at 27 days of age did not significantly affect interferon-α, interferon-γ, whereas Arg at 27 days of age significantly increased immunoglobulin G (p<0.05). These results revealed that arginine stimulates systematic immune response against intermediate plus strain of IBDV. |
| first_indexed | 2025-11-15T08:01:26Z |
| format | Article |
| id | upm-15102 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T08:01:26Z |
| publishDate | 2010 |
| publisher | Medwell Journals |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-151022018-09-26T02:38:45Z http://psasir.upm.edu.my/id/eprint/15102/ Immunostimulatory effects of arginine in broiler chickens challenged with vaccine strain of infectious bursal disease virus Emadi, Mozhdeh Jahanshiri, Fatemeh Jalilian, Farid Azizi Kaveh, Kamran Bejo, Mohd Hair Ideris, Aini Assumaidaee, A. A. Alimon, Abdul Razak Infectious Bursal Disease (IBD) continues to pose potential threat to poultry industry all over the world. The disease can spell disaster not only through its infection but also by break of immunity in chickens vaccinated for other diseases. On the other hand, arginine (Arg), a ubiquitous, semi-essential amino acid has emerged as an imunostimulant from variety of human and animal studies. In the present study, we demonstrate the stimulatory effects of Arg on systemic immune response in chickens challenged by orally administration of intermediate plus strain of IBD virus at 28 days of age. A corn-soybean meal based diet containing different levels of Arg (0, 0.67, 1.37, 2.07 and 2.77) for the starter, (0, 0.53, 1.1, 1.68 and 2.25) for the grower and (0, 0.52, 1.04, 1.56 and 2.08) for the finisher was used. In a completely randomized design with five treatments of five replicates each and 10 chickens per replicate, 250 Cobb500 male broiler chickens from 0-49 days of age were used. To measure the innate, cellular and humoral immunity indicators (interferon-α, interferon-γ, immunoglobulin G) at 27, 35, 42 and 49 days of age, serum samples from each replicate of treatments were collected and subjected to ELISA. The result showed that Arg supplementation in the chickens basal diets significantly increased the serum levels of interferon-α, interferon-γ, immunoglobulin G at 35, 42 and 49 days of age (p<0.05). The different levels of Arg at 27 days of age did not significantly affect interferon-α, interferon-γ, whereas Arg at 27 days of age significantly increased immunoglobulin G (p<0.05). These results revealed that arginine stimulates systematic immune response against intermediate plus strain of IBDV. Medwell Journals 2010 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/15102/1/Immunostimulatory%20effects%20of%20arginine%20in%20broiler%20chickens%20challenged%20with%20vaccine%20strain%20of%20infectious%20bursal%20disease%20virus.pdf Emadi, Mozhdeh and Jahanshiri, Fatemeh and Jalilian, Farid Azizi and Kaveh, Kamran and Bejo, Mohd Hair and Ideris, Aini and Assumaidaee, A. A. and Alimon, Abdul Razak (2010) Immunostimulatory effects of arginine in broiler chickens challenged with vaccine strain of infectious bursal disease virus. Journal of Animal and Veterinary Advances, 9 (3). pp. 594-600. ISSN 1680-5593 http://www.medwelljournals.com/abstract/?doi=javaa.2010.594.600 10.3923/javaa.2010.594.600 |
| spellingShingle | Emadi, Mozhdeh Jahanshiri, Fatemeh Jalilian, Farid Azizi Kaveh, Kamran Bejo, Mohd Hair Ideris, Aini Assumaidaee, A. A. Alimon, Abdul Razak Immunostimulatory effects of arginine in broiler chickens challenged with vaccine strain of infectious bursal disease virus |
| title | Immunostimulatory effects of arginine in broiler chickens challenged with vaccine strain of infectious bursal disease virus |
| title_full | Immunostimulatory effects of arginine in broiler chickens challenged with vaccine strain of infectious bursal disease virus |
| title_fullStr | Immunostimulatory effects of arginine in broiler chickens challenged with vaccine strain of infectious bursal disease virus |
| title_full_unstemmed | Immunostimulatory effects of arginine in broiler chickens challenged with vaccine strain of infectious bursal disease virus |
| title_short | Immunostimulatory effects of arginine in broiler chickens challenged with vaccine strain of infectious bursal disease virus |
| title_sort | immunostimulatory effects of arginine in broiler chickens challenged with vaccine strain of infectious bursal disease virus |
| url | http://psasir.upm.edu.my/id/eprint/15102/ http://psasir.upm.edu.my/id/eprint/15102/ http://psasir.upm.edu.my/id/eprint/15102/ http://psasir.upm.edu.my/id/eprint/15102/1/Immunostimulatory%20effects%20of%20arginine%20in%20broiler%20chickens%20challenged%20with%20vaccine%20strain%20of%20infectious%20bursal%20disease%20virus.pdf |