Executive function and attention span in euthymic patients with bipolar 1 disorder.
This is a cross secti onal co mparison study to assess executive function and attention span in euthymic p atients with bipolar 1 disorder. It compares the performance of these two cogn itive domains in 40 patients with bipolar 1 disorder to that of 40 healthy normal subjects using Trail Maki ng (TM...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
Malaysian Medical Association.
2010
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| Online Access: | http://psasir.upm.edu.my/id/eprint/14633/ http://psasir.upm.edu.my/id/eprint/14633/1/Executive%20function%20and%20attention%20span%20in%20euthymic%20patients%20with%20bipolar%201%20disorder2.pdf |
| _version_ | 1848842448168550400 |
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| author | Ibrahim, Normala Abdul Rahman, Abdul Hamid Baharuddin, Azlin Nik Jaafar, Nik Ruzyanei Zakaria, Hazli Shah, Shamsul Azhar |
| author_facet | Ibrahim, Normala Abdul Rahman, Abdul Hamid Baharuddin, Azlin Nik Jaafar, Nik Ruzyanei Zakaria, Hazli Shah, Shamsul Azhar |
| author_sort | Ibrahim, Normala |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | This is a cross secti onal co mparison study to assess executive function and attention span in euthymic p atients with bipolar 1 disorder. It compares the performance of these two cogn itive domains in 40 patients with bipolar 1 disorder to that of 40 healthy normal subjects using Trail Maki ng (TMT), Digit Span (Forward and Backward) and Ver bal Fluency (VF) tests. The association between demographic, clinical characteristics and performance in all tests were examined. Patients wit h bipola r illness showed significant impairment with moderate to large e ffect siz es (VF= 0.67, TMT A= 0.52, TMT B = 0.81, Digit Forward= 0.97, Digit ba ckward= 1.10) in all tasks of executive and atte ntion functioning. These impairments a re observed in the absence of active mood symptoms while duration and severity of illness are not found to have an e ffect on both cognitive domains. Medications received by patients with bipolar disorder have significant association with performance on executive tasks. The results of this study add on to the existing global evidence of cognitive impair ment in bipolar illness despite its cross cultural differences. Its presenc e in the absence of mania, depression or mixed episode indicates that cognitive impairmen t is stable even af ter symptoms recovery. |
| first_indexed | 2025-11-15T07:59:17Z |
| format | Article |
| id | upm-14633 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T07:59:17Z |
| publishDate | 2010 |
| publisher | Malaysian Medical Association. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-146332015-09-28T01:08:21Z http://psasir.upm.edu.my/id/eprint/14633/ Executive function and attention span in euthymic patients with bipolar 1 disorder. Ibrahim, Normala Abdul Rahman, Abdul Hamid Baharuddin, Azlin Nik Jaafar, Nik Ruzyanei Zakaria, Hazli Shah, Shamsul Azhar This is a cross secti onal co mparison study to assess executive function and attention span in euthymic p atients with bipolar 1 disorder. It compares the performance of these two cogn itive domains in 40 patients with bipolar 1 disorder to that of 40 healthy normal subjects using Trail Maki ng (TMT), Digit Span (Forward and Backward) and Ver bal Fluency (VF) tests. The association between demographic, clinical characteristics and performance in all tests were examined. Patients wit h bipola r illness showed significant impairment with moderate to large e ffect siz es (VF= 0.67, TMT A= 0.52, TMT B = 0.81, Digit Forward= 0.97, Digit ba ckward= 1.10) in all tasks of executive and atte ntion functioning. These impairments a re observed in the absence of active mood symptoms while duration and severity of illness are not found to have an e ffect on both cognitive domains. Medications received by patients with bipolar disorder have significant association with performance on executive tasks. The results of this study add on to the existing global evidence of cognitive impair ment in bipolar illness despite its cross cultural differences. Its presenc e in the absence of mania, depression or mixed episode indicates that cognitive impairmen t is stable even af ter symptoms recovery. Malaysian Medical Association. 2010-09 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/14633/1/Executive%20function%20and%20attention%20span%20in%20euthymic%20patients%20with%20bipolar%201%20disorder2.pdf Ibrahim, Normala and Abdul Rahman, Abdul Hamid and Baharuddin, Azlin and Nik Jaafar, Nik Ruzyanei and Zakaria, Hazli and Shah, Shamsul Azhar (2010) Executive function and attention span in euthymic patients with bipolar 1 disorder. Medical Journal of Malaysia, 65 (3). pp. 192-196. ISSN 0300-5283 English |
| spellingShingle | Ibrahim, Normala Abdul Rahman, Abdul Hamid Baharuddin, Azlin Nik Jaafar, Nik Ruzyanei Zakaria, Hazli Shah, Shamsul Azhar Executive function and attention span in euthymic patients with bipolar 1 disorder. |
| title | Executive function and attention span in euthymic patients with bipolar 1 disorder. |
| title_full | Executive function and attention span in euthymic patients with bipolar 1 disorder. |
| title_fullStr | Executive function and attention span in euthymic patients with bipolar 1 disorder. |
| title_full_unstemmed | Executive function and attention span in euthymic patients with bipolar 1 disorder. |
| title_short | Executive function and attention span in euthymic patients with bipolar 1 disorder. |
| title_sort | executive function and attention span in euthymic patients with bipolar 1 disorder. |
| url | http://psasir.upm.edu.my/id/eprint/14633/ http://psasir.upm.edu.my/id/eprint/14633/1/Executive%20function%20and%20attention%20span%20in%20euthymic%20patients%20with%20bipolar%201%20disorder2.pdf |