Eurycomanone induce apoptosis in HepG2 cells via up-regulation of p53

QR Code

Eurycomanone induce apoptosis in HepG2 cells via up-regulation of p53

Background: Eurycomanone is a cytotoxic compound found in Eurycoma longifolia Jack. Previous studies had noted the cytotoxic effect against various cancer cell lines. The aim of this study is to investigate the cytotoxicity against human hepato carcinoma cell in vitro and the mode of action. The c...

Full description

Bibliographic Details
Main Authors:	Zakaria, Yusmazura, Rahmat, Asmah, Lope Pihie, Azimahtol Hawariah, Abdullah, Noor Rain, Houghton, Peter J.
Format:	Article
Language:	English
Published:	BioMed Central 2009
Online Access:	http://psasir.upm.edu.my/id/eprint/14582/ http://psasir.upm.edu.my/id/eprint/14582/1/14582.pdf

Similar Items

Regulation of p53-, Bcl-2- and Caspase-dependent Signaling Pathway in Xanthorrhizol-induced Apoptosis of HepG2 Hepatoma Cells
by: Tri Handayani,, et al.
Published: (2007)

Zerumbone Exerts Antiproliferative Activity via Apoptosis on HepG2 Cells
by: Syed Alwi, Sharifah Sakinah, et al.
Published: (2007)

Suppression effect of eurycomanone on the growth of HepG2 tumour transplanted in mice
by: Zakaria, Yusmazura
Published: (2011)

Xanthorrhizol Induces Apoptosis Via the Up-regulation of Bax and p53 in HeLa Cells
by: Ismail, Norzila, et al.
Published: (2005)

Xanthorrhizol Induces Apoptosis Via the Up-regulation of Bax and p53 in HeLa Cells
by: Ismail, Norzila, et al.
Published: (2005)

Eurycomanone exerts antiproliferative activity via apoptosis upon MCF-7 cells
by: Cheah, Shiau Chuen, et al.
Published: (2004)

Suppression Effect of Eurycomanone on the Growth of Human Hepatoma Cells (Hepg2) by Inducing P53-Mediated Apoptotic Pathway
by: Zakaria, Yusmazura
Published: (2009)

Garcinia Dulcis fruit extract induced Cytotoxicity and Apoptosis in HepG2 liver cancer cell line
by: Abu Bakar, Mohd Fadzelly, et al.
Published: (2015)

Effect of ximenynic acid on cell cycle arrest and apoptosis and COX-1 in HepG2 cells
by: Cai, F., et al.
Published: (2016)

Cytotoxicty of zerumbone against liver cancer cell lines (HepG2) via apoptosis activity
by: Abdul Samad, Nozlena, et al.
Published: (2014)

Clausenidin from Clausena excavata induces apoptosis in hepG2 cells via the mitochondrial pathway
by: Waziri, Peter M., et al.
Published: (2016)

Cytotoxic Effect of Girinimbine on HepG2 Cells
by: Mohan, Suvita Syam
Published: (2011)

Vanillin rich fraction regulates LDLR and HMGCR gene expression in HepG2 cells.
by: Ismail, Maznah, et al.
Published: (2010)

Antioxidant behaviour of carotenoids highly accumulated in HepG2 cells
by: Jaswir, Irwandi, et al.
Published: (2012)

Selective cytotoxicity of goniothalamin against hepatoblastoma HepG2 cells.
by: Al-Qubaisi, Mothanna, et al.
Published: (2011)

Adverse effects of anti-tuberculosis drugs on HepG2 cell bioenergetics
by: Elmorsy, E., et al.
Published: (2016)

Gamma-tocotrienol alters protein expression of HepG2 cell line
by: Farahani ARS,, et al.
Published: (2008)

Induction of apoptosis by gluconasturtiin-isothiocyanate (GNST-ITC) in human hepatocarcinoma HepG2 cells and human breast adenocarcinoma MCF-7 cells
by: Arumugam, Asvinidevi, et al.
Published: (2020)

Cytotoxicity of Clinacanthus Nutans Extracts on Human Hepatoma (HepG2) Cell Line
by: Hazrulrizawati, Hamid, et al.
Published: (2016)

Role of oxidative stress in antituberculous drugs (individuals and combined) cytotoxicity in HepG2 cells
by: Elmorsy, Ekramy, et al.
Published: (2016)

Cytotoxic effects of conjugated linoleic acids on human hepatoma cancer cells (HepG2)
by: Melaku, Achenef, et al.
Published: (2012)

Production and characterization of phycobiliproteins from cyanobacteria and their effects on HepG2 cancer cell lines
by: Begium, Hasina
Published: (2014)

Effects of thymoquinone and thymoquinone-loaded nanostructured lipid carrier on hepatocellular carcinoma cell models, Hep3B and HepG2
by: Haron, Aminah Suhaila
Published: (2017)

Construction of blackberry polysaccharide nano-selenium particles: Structure features and regulation effects of glucose/lipid metabolism in HepG2 cells
by: Zu-Man, Dou, et al.
Published: (2024)

Anti-proliferation of MDA-MB-231 cells by Averrhoa bilimbi extract is associated with G0/G1 perturbation and mitochondria-mediated apoptosis independent of p53
by: Yan, See Wan, et al.
Published: (2017)

Protective effects of the extracts of Barringtonia racemosa shoots against oxidative damage in HepG2 cells
by: Kong, Kin Weng, et al.
Published: (2016)

Thymoquinone-loaded nanostructured lipid carrier reduces proliferation of human liver cancer cells, HepG2
by: Mustafa Azmy, Nurfahima, et al.
Published: (2019)

Hippurate-Zinc layered Hydroxide Nanohybrid and its synergistic effect with Tamoxifen on the HepG2 cell lines.
by: Hussein, Mohd. Zobir, et al.
Published: (2011)

Styrylpyrone derivative (SPD) induces cancer cell death by activating the cell's intrinsic apoptotic machinery
by: Nallappan, Meenakshii, et al.
Published: (2009)

A bismuth diethyldithiocarbamate compound promotes apoptosis in HepG2 carcinoma, cell cycle arrest and inhibits cell invasion through modulation of the NF-κB activation pathway
by: Abang Ishak, Dayang Hazwani, et al.
Published: (2014)

Antioxidative and photocytotoxic effects of standardized Clinacanthus nutans and Strobilanthes crispus extracts toward HepG2 liver cells
by: Tan, Sheri-Ann, et al.
Published: (2019)

Antiproliferative effects of zerumbone-hydroxypropyl-ß-cyclodextrin inclusion complex on HepG2 liver cancer cells in vitro
by: Muhammad Nadzri, Nabilah
Published: (2013)

New method for improving solubilization and uptake of lutein and carotenoids in human hepatocellular liver carcinoma (HepG2) cell culture
by: Lestari, Widya, et al.
Published: (2014)

New Method for Improving solubilization and uptake of lutein and carotenoids in human hepatocellular liver carcinoma (HepG2) cell culture
by: Jaswir, Irwandi, et al.
Published: (2009)

Improvement of solubilization and uptake of dietary antioxidants in human hepatocellular liver carcinoma (HepG2) cell line (PDNP4)
by: Jaswir, Irwandi, et al.
Published: (2009)

Human Hepatitis B Viral Proteins HBX and HBE: Roles in HepG2 Cell Line Survival and Cell Death
by: Holme, Andrea Lisa
Published: (2004)

Regulation of low-density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression by thymoquinone-rich fraction and thymoquinone in HepG2 cells
by: Al-Naqeep, Ghanya, et al.
Published: (2009)

Monechma ciliatum methanolic extract regulates low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase genes expression in HepG2 cells
by: Mariot, Abdalbasit Adam, et al.
Published: (2010)

Cytotoxic effect of konjac glucomannan on the molecular and dielectric properties of HepG2 and WRL68 liver cell lines / Sakunie Sawai
by: Sakunie , Sawai
Published: (2019)

New method for improving solubilization and uptake of lutein and beta-carotene in human hepatocellular liver carcinoma (HepG2) cell culture
by: Jaswir, Irwandi, et al.
Published: (2010)