Effects of Strobilanthes crispus juice on wound healing and antioxidant enzymes in normal and streptozotocin-induced diabetic rats.

The objective of this study is to determine the effect of Strobilanthes crispus Juice (SCJ) on wound healing and antioxidative enzymes activity in normal and streptozotocin-induced rats. A total of 48 male albino Sprague dawley rats, weight 150-200 g were used. The rats were divided into 8 groups wi...

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Main Authors: Noor Azmi, Norfarizan Hanoon, Rahmat, Asmah, Mohd. Yusof, Rokiah, Othman, Fauziah, Hussin, Faridah
Format: Article
Language:English
English
Published: Asian Network for Scientific Information 2009
Online Access:http://psasir.upm.edu.my/id/eprint/14415/
http://psasir.upm.edu.my/id/eprint/14415/1/Effects%20of%20Strobilanthes%20crispus%20juice%20on%20wound%20healing%20and%20antioxidant%20enzymes%20in%20normal%20and%20streptozotocin.pdf
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author Noor Azmi, Norfarizan Hanoon
Rahmat, Asmah
Mohd. Yusof, Rokiah
Othman, Fauziah
Hussin, Faridah
author_facet Noor Azmi, Norfarizan Hanoon
Rahmat, Asmah
Mohd. Yusof, Rokiah
Othman, Fauziah
Hussin, Faridah
author_sort Noor Azmi, Norfarizan Hanoon
building UPM Institutional Repository
collection Online Access
description The objective of this study is to determine the effect of Strobilanthes crispus Juice (SCJ) on wound healing and antioxidative enzymes activity in normal and streptozotocin-induced rats. A total of 48 male albino Sprague dawley rats, weight 150-200 g were used. The rats were divided into 8 groups with 6 rats in each group. The healing of 2 cm linear incisions created on the back of each rat was monitored by measuring the length of the wounds daily. The result showed a significant increase (p<0.05) in the percentage of wound healing at day 3 and 7 in the treated group especially treated with 140 mg kg-1 b.wt. of S. crispus juice in diabetic and normal rats compared with the control. Strobilanthes crispus juice increased significantly p (<0.05) of glutathione peroxidase (GPx) and superoxide dismutase (SOD) activity in treated group in diabetic rats. Significant correlation was found between wound healing, GPx and SOD enzymes. In conclusion, S. crispus juice enhanced wound healing in normal and diabetic rats.
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institution Universiti Putra Malaysia
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language English
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publishDate 2009
publisher Asian Network for Scientific Information
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spelling upm-144152015-12-18T03:23:02Z http://psasir.upm.edu.my/id/eprint/14415/ Effects of Strobilanthes crispus juice on wound healing and antioxidant enzymes in normal and streptozotocin-induced diabetic rats. Noor Azmi, Norfarizan Hanoon Rahmat, Asmah Mohd. Yusof, Rokiah Othman, Fauziah Hussin, Faridah The objective of this study is to determine the effect of Strobilanthes crispus Juice (SCJ) on wound healing and antioxidative enzymes activity in normal and streptozotocin-induced rats. A total of 48 male albino Sprague dawley rats, weight 150-200 g were used. The rats were divided into 8 groups with 6 rats in each group. The healing of 2 cm linear incisions created on the back of each rat was monitored by measuring the length of the wounds daily. The result showed a significant increase (p<0.05) in the percentage of wound healing at day 3 and 7 in the treated group especially treated with 140 mg kg-1 b.wt. of S. crispus juice in diabetic and normal rats compared with the control. Strobilanthes crispus juice increased significantly p (<0.05) of glutathione peroxidase (GPx) and superoxide dismutase (SOD) activity in treated group in diabetic rats. Significant correlation was found between wound healing, GPx and SOD enzymes. In conclusion, S. crispus juice enhanced wound healing in normal and diabetic rats. Asian Network for Scientific Information 2009 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/14415/1/Effects%20of%20Strobilanthes%20crispus%20juice%20on%20wound%20healing%20and%20antioxidant%20enzymes%20in%20normal%20and%20streptozotocin.pdf Noor Azmi, Norfarizan Hanoon and Rahmat, Asmah and Mohd. Yusof, Rokiah and Othman, Fauziah and Hussin, Faridah (2009) Effects of Strobilanthes crispus juice on wound healing and antioxidant enzymes in normal and streptozotocin-induced diabetic rats. Journal of Biological Sciences, 9 (7). pp. 662-668. ISSN 1727-3048, ESSN : 1812-5719 10.3923/jbs.2009.662.668 English
spellingShingle Noor Azmi, Norfarizan Hanoon
Rahmat, Asmah
Mohd. Yusof, Rokiah
Othman, Fauziah
Hussin, Faridah
Effects of Strobilanthes crispus juice on wound healing and antioxidant enzymes in normal and streptozotocin-induced diabetic rats.
title Effects of Strobilanthes crispus juice on wound healing and antioxidant enzymes in normal and streptozotocin-induced diabetic rats.
title_full Effects of Strobilanthes crispus juice on wound healing and antioxidant enzymes in normal and streptozotocin-induced diabetic rats.
title_fullStr Effects of Strobilanthes crispus juice on wound healing and antioxidant enzymes in normal and streptozotocin-induced diabetic rats.
title_full_unstemmed Effects of Strobilanthes crispus juice on wound healing and antioxidant enzymes in normal and streptozotocin-induced diabetic rats.
title_short Effects of Strobilanthes crispus juice on wound healing and antioxidant enzymes in normal and streptozotocin-induced diabetic rats.
title_sort effects of strobilanthes crispus juice on wound healing and antioxidant enzymes in normal and streptozotocin-induced diabetic rats.
url http://psasir.upm.edu.my/id/eprint/14415/
http://psasir.upm.edu.my/id/eprint/14415/
http://psasir.upm.edu.my/id/eprint/14415/1/Effects%20of%20Strobilanthes%20crispus%20juice%20on%20wound%20healing%20and%20antioxidant%20enzymes%20in%20normal%20and%20streptozotocin.pdf