Effect of modification of the physicochemical properties of ICAM-1-derived peptides on internalization and intracellular distribution in the human leukemic cell line HL-60

Effect of modification of the physicochemical properties of ICAM-1-derived peptides on internalization and intracellular distribution in the human leukemic cell line HL-60

The objective of this work is to test the hypothesis that increasing the hydrophilicity of DOX−peptide conjugates may modify their entry mechanisms into HL-60 cells from passive diffusion to receptor-mediated uptake. To test this hypothesis, the entry mechanisms and the intracellular disposition of...

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Bibliographic Details
Main Authors: Majumdar, Sumit, Tejo, Bimo Ario, Badawi, Ahmed H., Moore, David, Krise, Jeffrey P., Siahaan, Teruna J.
Format: Article
Language:English
Published: American Chemical Society 2009
Online Access:http://psasir.upm.edu.my/id/eprint/14272/
http://psasir.upm.edu.my/id/eprint/14272/1/Effect%20of%20modification%20of%20the%20physicochemical%20properties%20of%20ICAM.pdf

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