Cytotoxic effect of gentamycin-coated hydroxyapatite on Staphylococcus aureus biofilm.
A biofilm is a multilayered complex microorganism, which attached on a surface and resistant to antibiotics. In this study, we examined the cytotoxicity of the HA biomaterial coated with gentamycin on S. aureus biofilm. The microtiter plate biofilm assay and catheter-associated biofilm had been desc...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English English |
| Published: |
Electron Microscopy Society of Malaysia
2009
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/13861/ http://psasir.upm.edu.my/id/eprint/13861/1/Cytotoxic%20effect%20of%20gentamycin.pdf |
| _version_ | 1848842231454105600 |
|---|---|
| author | Au, Lee Fong Othman, Fauziah Rahmat, Asmah M., Rusnah Besar, Idris Vidyadaran, Sharmili Md. Akim, Abdah Goriman Khan, Mohd Azam Khan Morteza , Saidi Ahmad, Azfar Rizal |
| author_facet | Au, Lee Fong Othman, Fauziah Rahmat, Asmah M., Rusnah Besar, Idris Vidyadaran, Sharmili Md. Akim, Abdah Goriman Khan, Mohd Azam Khan Morteza , Saidi Ahmad, Azfar Rizal |
| author_sort | Au, Lee Fong |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | A biofilm is a multilayered complex microorganism, which attached on a surface and resistant to antibiotics. In this study, we examined the cytotoxicity of the HA biomaterial coated with gentamycin on S. aureus biofilm. The microtiter plate biofilm assay and catheter-associated biofilm had been described in this study. The surface morphology of S. aureus biofilm was examined under scanning electron microscope (SEM). The IC50 of gentamycincoated HA treated on S. aureus biofilm was 0.1mg/ml (100μg/ml). |
| first_indexed | 2025-11-15T07:55:51Z |
| format | Article |
| id | upm-13861 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T07:55:51Z |
| publishDate | 2009 |
| publisher | Electron Microscopy Society of Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-138612015-11-23T01:52:08Z http://psasir.upm.edu.my/id/eprint/13861/ Cytotoxic effect of gentamycin-coated hydroxyapatite on Staphylococcus aureus biofilm. Au, Lee Fong Othman, Fauziah Rahmat, Asmah M., Rusnah Besar, Idris Vidyadaran, Sharmili Md. Akim, Abdah Goriman Khan, Mohd Azam Khan Morteza , Saidi Ahmad, Azfar Rizal A biofilm is a multilayered complex microorganism, which attached on a surface and resistant to antibiotics. In this study, we examined the cytotoxicity of the HA biomaterial coated with gentamycin on S. aureus biofilm. The microtiter plate biofilm assay and catheter-associated biofilm had been described in this study. The surface morphology of S. aureus biofilm was examined under scanning electron microscope (SEM). The IC50 of gentamycincoated HA treated on S. aureus biofilm was 0.1mg/ml (100μg/ml). Electron Microscopy Society of Malaysia 2009 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/13861/1/Cytotoxic%20effect%20of%20gentamycin.pdf Au, Lee Fong and Othman, Fauziah and Rahmat, Asmah and M., Rusnah and Besar, Idris and Vidyadaran, Sharmili and Md. Akim, Abdah and Goriman Khan, Mohd Azam Khan and Morteza , Saidi and Ahmad, Azfar Rizal (2009) Cytotoxic effect of gentamycin-coated hydroxyapatite on Staphylococcus aureus biofilm. Malaysian Journal of Microscopy, 5 (1). ISSN 1823-7010 English |
| spellingShingle | Au, Lee Fong Othman, Fauziah Rahmat, Asmah M., Rusnah Besar, Idris Vidyadaran, Sharmili Md. Akim, Abdah Goriman Khan, Mohd Azam Khan Morteza , Saidi Ahmad, Azfar Rizal Cytotoxic effect of gentamycin-coated hydroxyapatite on Staphylococcus aureus biofilm. |
| title | Cytotoxic effect of gentamycin-coated hydroxyapatite on Staphylococcus aureus biofilm. |
| title_full | Cytotoxic effect of gentamycin-coated hydroxyapatite on Staphylococcus aureus biofilm. |
| title_fullStr | Cytotoxic effect of gentamycin-coated hydroxyapatite on Staphylococcus aureus biofilm. |
| title_full_unstemmed | Cytotoxic effect of gentamycin-coated hydroxyapatite on Staphylococcus aureus biofilm. |
| title_short | Cytotoxic effect of gentamycin-coated hydroxyapatite on Staphylococcus aureus biofilm. |
| title_sort | cytotoxic effect of gentamycin-coated hydroxyapatite on staphylococcus aureus biofilm. |
| url | http://psasir.upm.edu.my/id/eprint/13861/ http://psasir.upm.edu.my/id/eprint/13861/1/Cytotoxic%20effect%20of%20gentamycin.pdf |