Cytotoxic effect of damnacanthal, nordamnacanthal, zerumbone and betulinic acid isolated from Malaysian plant sources
The present study was to evaluate the toxicity of damnacanthal, nordamnacanthal, betulinic acid and zerumbone isolated from local medicinal plants towards leukemia cell lines and immune cells by using MTT assay and flow cytometry cell cycle analysis. The results showed that damnacanthal significantl...
| Main Authors: | Mohamed Alitheen, Noorjahan Banu, Abd Rahman, Mashitoh, Yeap, Swee Keong, Mustafa, Shuhaimi, Ali, Abdul Manaf, Lajis, Nordin |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Faculty of Food Science and Technology, Universiti Putra Malaysia
2010
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/13860/ http://psasir.upm.edu.my/id/eprint/13860/1/Cytotoxic%20Effect%20of%20Damnacanthal%2C%20Nordamnacanthal%2C%20Zerumbone%20and%20Betulinic%20Acid%20Isolated%20from%20Malaysian%20Plant%20Sources.pdf |
Similar Items
Cytotoxicity and immunomodulatory effects of damnacanthal and nordamnacanthal isolated from roots of morinda elliptica.
by: Mohamed Alitheen, Noorjahan Banu, et al.
Published: (2010)
by: Mohamed Alitheen, Noorjahan Banu, et al.
Published: (2010)
Effects of Damnacanthal, Nordamnacanthal, Betulinic Acid and Zerumbone Isolated from Local Medicinal Plants on Leukemia Cell Lines and Immune Cells
by: Abd Rahman, Mashitoh
Published: (2007)
by: Abd Rahman, Mashitoh
Published: (2007)
Total Synthesis, Cytotoxic Effects of Damnacanthal, Nordamnacanthal and Related Anthraquinone Analogues
by: Akhtar, Muhammad Nadeem, et al.
Published: (2013)
by: Akhtar, Muhammad Nadeem, et al.
Published: (2013)
Total synthesis, cytotoxic effects of damnacanthal, nordamnacanthal and related anthraquinone analogues
by: Akhtar, Muhammad Nadeem, et al.
Published: (2013)
by: Akhtar, Muhammad Nadeem, et al.
Published: (2013)
Immunomodulatory effects of damnacanthal isolated from roots of Morinda elliptica
by: Mohammed Alitheen, Noorjahan Banu, et al.
Published: (2010)
by: Mohammed Alitheen, Noorjahan Banu, et al.
Published: (2010)
Cytotoxic properties of anthraquinones (nordamnacanthal and damnacanthal) from roots of Morinda elliptica
by: Saiful Yazan, Latifah
Published: (2003)
by: Saiful Yazan, Latifah
Published: (2003)
Cytotoxic effect of betulinic acid and betulinic acid acetate isolated from Melaleuca cajuput on human myeloid leukemia (HL-60) cell line
by: Faujan, Nur Hana, et al.
Published: (2010)
by: Faujan, Nur Hana, et al.
Published: (2010)
Immunomodulatory effects of zerumbone isolated from roots of Zingiber zerumbet.
by: Keong, Yeap Swee, et al.
Published: (2010)
by: Keong, Yeap Swee, et al.
Published: (2010)
Anticancer potential of Damnacanthal and Nordamnacanthal from Morinda elliptica roots on T-lymphoblastic leukemia cells
by: Saiful Yazan, Latifah, et al.
Published: (2021)
by: Saiful Yazan, Latifah, et al.
Published: (2021)
Nordamnacanthal potentiates the cytotoxic effects of tamoxifen in human breast cancer cells
by: Mohamed Alitheen, Noorjahan Banu, et al.
Published: (2015)
by: Mohamed Alitheen, Noorjahan Banu, et al.
Published: (2015)
Immunomodulatory effects of betulinic acid isolation from the bark of Melaleuca cajuputi
by: Abd Rahman, Mashitoh, et al.
Published: (2012)
by: Abd Rahman, Mashitoh, et al.
Published: (2012)
Ultrastructural and morphological effects in T-Lymphoblastic leukaemia, CEM-SS Cells following treatment with Nordamnacanthal and Damnacanthal from Roots of Morinda elliptica
by: Saiful Yazan, Latifah, et al.
Published: (2021)
by: Saiful Yazan, Latifah, et al.
Published: (2021)
Ultrastructural and morphological effects in T-lymphoblastic leukemia CEM-SS cells following treatment with nordamnacanthal and damnacanthal from roots of Morinda elliptica
by: Latifah, Saiful Yazan, et al.
Published: (2022)
by: Latifah, Saiful Yazan, et al.
Published: (2022)
Damnacanthal: a promising compound as a medicinal anthraquinone
by: Abu, Nadiah, et al.
Published: (2014)
by: Abu, Nadiah, et al.
Published: (2014)
Combinatorial Cytotoxic Effects of Damnacanthal and Doxorubicin Against Human Breast Cancer MCF-7 Cells in Vitro
by: Muhammad Yusran, Abdul Aziz, et al.
Published: (2016)
by: Muhammad Yusran, Abdul Aziz, et al.
Published: (2016)
Combinatorial cytotoxic effects of damnacanthal and doxorubicin against human breast cancer MCF-7 cells in vitro
by: Abdul Aziz, Muhammad Yusran, et al.
Published: (2016)
by: Abdul Aziz, Muhammad Yusran, et al.
Published: (2016)
Cytotoxic effects of damnacanthal and damnacanthal-doxorubicin combination on human breast cancer cell line (MCF-7)
by: Abdul Aziz, Muhammad Yusran
Published: (2012)
by: Abdul Aziz, Muhammad Yusran
Published: (2012)
Cytotoxic effect of 2’, 3’-epoxy isocapnolactone and 8-hydroxyisocapnolactone-2’3’-diol isolated from Micromelum minutum (G.Forst.) Wight and Arn. in human T-lymphocyte leukemia CEM-SS cells
by: Tan, Kar Ban, et al.
Published: (2009)
by: Tan, Kar Ban, et al.
Published: (2009)
Synergistic cytotoxicity between elephantopus scaber and tamoxifen on MCF-7-derived multicellular tumor spheroid
by: Ho, Wan Yong, et al.
Published: (2021)
by: Ho, Wan Yong, et al.
Published: (2021)
Damnacanthal is a potent inducer of apoptosis with anticancer activity by stimulating p53 and p21 genes in MCF-7 breast cancer cells
by: Abdul Aziz, Muhammad Yusran, et al.
Published: (2014)
by: Abdul Aziz, Muhammad Yusran, et al.
Published: (2014)
Cytotoxic Effect of Betulinic Acid on Vascular Smooth Muscle Cells
by: Vadivelu, Raja Kumar
Published: (2009)
by: Vadivelu, Raja Kumar
Published: (2009)
Selective cytotoxicity of goniothalamin against hepatoblastoma HepG2 cells.
by: Al-Qubaisi, Mothanna, et al.
Published: (2011)
by: Al-Qubaisi, Mothanna, et al.
Published: (2011)
Immunomodulatory effect of Rhaphidophora korthalsii on natural killer cell cytotoxicity.
by: Yeap, Swee Keong, et al.
Published: (2012)
by: Yeap, Swee Keong, et al.
Published: (2012)
Rhaphidophora korthalsii modulates peripheral blood natural killer cell proliferation, cytokine secretion and cytotoxicity
by: Yeap, Swee Keong, et al.
Published: (2013)
by: Yeap, Swee Keong, et al.
Published: (2013)
Design, synthesis and cytotoxic effects of curcumin derivatives on K562, MCF-7 and MDA-MB-231 cancer cell lines
by: Akhtar, Muhammad Nadeem, et al.
Published: (2018)
by: Akhtar, Muhammad Nadeem, et al.
Published: (2018)
Cytotoxic evaluation of Leptospermum javanicum and Baeckea frutescens along with the anti-cancer activities of the active isolate, betulinic acid / Suerialoasan Navanesan
by: Suerialoasan , Navanesan
Published: (2018)
by: Suerialoasan , Navanesan
Published: (2018)
Cytotoxic Effects of Zerumbone on Ovarian and Cervical Cancer Cell Lines
by: Mohd Zain, Zetty Nadia
Published: (2005)
by: Mohd Zain, Zetty Nadia
Published: (2005)
Bcl-2 was downregulated in G2/M-arrest breast cancer cells MCF-7-treated with nordamnacanthal
by: Saiful Yazan, Latifah, et al.
Published: (2010)
by: Saiful Yazan, Latifah, et al.
Published: (2010)
Extraction, isolation and purification of betulinic acid from Melaleuca sp.
by: Ahmad, Faujan, et al.
Published: (2002)
by: Ahmad, Faujan, et al.
Published: (2002)
Extraction, isolation and purification of betulinic acid from Melaleuca sp.
by: Ahmad, F. B. H., et al.
Published: (1999)
by: Ahmad, F. B. H., et al.
Published: (1999)
Characterisation of Plant Derived Damnacanthal and Nordamnacantbal Induced Cytotoxicity on Human HT29 Colon Adenocarcinoma Cell Line
by: Khor, Tin Oo
Published: (2001)
by: Khor, Tin Oo
Published: (2001)
Lipase catalyzed betulinic acid derivatives and its cytotoxic activity / Yamin Yasin and Faujan Ahmad
by: Ahmad, Faujan
Published: (2010)
by: Ahmad, Faujan
Published: (2010)
Sustained release and cytotoxicity evaluation of carbon nanotube-mediated drug delivery system for betulinic acid
by: Tan, Julia Meihua, et al.
Published: (2014)
by: Tan, Julia Meihua, et al.
Published: (2014)
Cytotoxic effects of commercial wheatgrass and fiber towards human acute promyelocytic leukemia cells (HL60).
by: Mohamed Alitheen, Noorjahan Banu, et al.
Published: (2011)
by: Mohamed Alitheen, Noorjahan Banu, et al.
Published: (2011)
Elephantopus scaber induces cytotoxicity in MCF-7 human breast cancer cells via p53-induced apoptosis.
by: Ho, Wan Yong, et al.
Published: (2011)
by: Ho, Wan Yong, et al.
Published: (2011)
Cytotoxic Effects of Betulinic Acid and its Derivatives on Human Myeloid Leukemia (Hl-60) Cell Line
by: Faujan, Nur Hana
Published: (2008)
by: Faujan, Nur Hana
Published: (2008)
Cytotoxic effect of ethanol extract of microalga, Chaetoceros calcitrans, and its mechanisms in inducing apoptosis in human breast cancer cell line
by: Nigjeh, Siyamak Ebrahimi, et al.
Published: (2013)
by: Nigjeh, Siyamak Ebrahimi, et al.
Published: (2013)
Zerumbone induces cytotoxicity and inhibits cell migration of human colon cancer cells
by: Tan, Min Jien, et al.
Published: (2020)
by: Tan, Min Jien, et al.
Published: (2020)
Nordamnacanthal induced apoptosis and mitotic-G2/M arrest with downregulation of Bcl-2 in the human breast cancer cell line (MCF-7).
by: Ishak , Norsyafini, et al.
Published: (2010)
by: Ishak , Norsyafini, et al.
Published: (2010)
Characterisation of sol–gel method synthesised MgZnFe2O4 nanoparticles and its cytotoxic effects on breast cancer cell line, MDA MB-231 in vitro
by: Nordin, Noraini, et al.
Published: (2017)
by: Nordin, Noraini, et al.
Published: (2017)
Similar Items
-
Cytotoxicity and immunomodulatory effects of damnacanthal and nordamnacanthal isolated from roots of morinda elliptica.
by: Mohamed Alitheen, Noorjahan Banu, et al.
Published: (2010) -
Effects of Damnacanthal, Nordamnacanthal, Betulinic Acid and Zerumbone Isolated from Local Medicinal Plants on Leukemia Cell Lines and Immune Cells
by: Abd Rahman, Mashitoh
Published: (2007) -
Total Synthesis, Cytotoxic Effects of Damnacanthal, Nordamnacanthal and Related Anthraquinone Analogues
by: Akhtar, Muhammad Nadeem, et al.
Published: (2013) -
Total synthesis, cytotoxic effects of damnacanthal, nordamnacanthal and related anthraquinone analogues
by: Akhtar, Muhammad Nadeem, et al.
Published: (2013) -
Immunomodulatory effects of damnacanthal isolated from roots of Morinda elliptica
by: Mohammed Alitheen, Noorjahan Banu, et al.
Published: (2010)