An improved artificial neural network based model for prediction of late onset heart failure

Background and Objective: The present study aims to present an artificial neural network (ANN)-based model for prediction of Late Onset Heart Failure (LOHF) in patients, with no previous Heart Failure (HF) history, who experienced non-fatal, first-ever Acute Myocardial Infarction (AMI) without previo...

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Main Authors: Salari, Nader, Shohaimi, Shamarina, Najafi, Farid, Nallappan, Meenakshii, Karishnarajah, Isthrinayagy
Format: Article
Language:English
Published: Marsland Press 2012
Online Access:http://psasir.upm.edu.my/id/eprint/13846/
http://psasir.upm.edu.my/id/eprint/13846/1/An%20improved%20artificial%20neural%20network%20based%20model%20for%20prediction%20of%20late%20onset%20heart%20failure.pdf
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author Salari, Nader
Shohaimi, Shamarina
Najafi, Farid
Nallappan, Meenakshii
Karishnarajah, Isthrinayagy
author_facet Salari, Nader
Shohaimi, Shamarina
Najafi, Farid
Nallappan, Meenakshii
Karishnarajah, Isthrinayagy
author_sort Salari, Nader
building UPM Institutional Repository
collection Online Access
description Background and Objective: The present study aims to present an artificial neural network (ANN)-based model for prediction of Late Onset Heart Failure (LOHF) in patients, with no previous Heart Failure (HF) history, who experienced non-fatal, first-ever Acute Myocardial Infarction (AMI) without previous history of heart failure. Methods: Two models of multilayer perceptron (MLP) and Radial Basis Function (RBF) neural network approaches based on decision support system were developed. The MLP model was used to optimize the predicting algorithm based on the conjugate gradients descent method. To design the RBF network, K-Means clustering technique was used to select the centers of RBFs, and k-nearest neighbourhood to define the spread and forward selection for determining the optimum number of RBFs. To assess the generalization of the network, K-fold cross-validation test was used. A total of 3,109 medical records containing 19 main clinical parameters were used to train and test the networks. Results: The findings indicate a reliable performance of the proposed system. The MLP based model yields a sensitivity, specificity, and an area under the receiver/relative operating characteristic (ROC) curve (AUC) of 87.1%, 90%, and 0.887 ± 0.02, respectively. However, the RBF network shows the above parameters as 84.4%, 94.3%, and 0.905 ± 0.017, respectively. Conclusions: The proposed intelligence system achieved a high degree of diagnostic accuracy (92.9% for MLP and 93.7% for RBF) indicating its high efficiency for clinical diagnosis of LOHF.
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spelling upm-138462018-08-14T08:48:54Z http://psasir.upm.edu.my/id/eprint/13846/ An improved artificial neural network based model for prediction of late onset heart failure Salari, Nader Shohaimi, Shamarina Najafi, Farid Nallappan, Meenakshii Karishnarajah, Isthrinayagy Background and Objective: The present study aims to present an artificial neural network (ANN)-based model for prediction of Late Onset Heart Failure (LOHF) in patients, with no previous Heart Failure (HF) history, who experienced non-fatal, first-ever Acute Myocardial Infarction (AMI) without previous history of heart failure. Methods: Two models of multilayer perceptron (MLP) and Radial Basis Function (RBF) neural network approaches based on decision support system were developed. The MLP model was used to optimize the predicting algorithm based on the conjugate gradients descent method. To design the RBF network, K-Means clustering technique was used to select the centers of RBFs, and k-nearest neighbourhood to define the spread and forward selection for determining the optimum number of RBFs. To assess the generalization of the network, K-fold cross-validation test was used. A total of 3,109 medical records containing 19 main clinical parameters were used to train and test the networks. Results: The findings indicate a reliable performance of the proposed system. The MLP based model yields a sensitivity, specificity, and an area under the receiver/relative operating characteristic (ROC) curve (AUC) of 87.1%, 90%, and 0.887 ± 0.02, respectively. However, the RBF network shows the above parameters as 84.4%, 94.3%, and 0.905 ± 0.017, respectively. Conclusions: The proposed intelligence system achieved a high degree of diagnostic accuracy (92.9% for MLP and 93.7% for RBF) indicating its high efficiency for clinical diagnosis of LOHF. Marsland Press 2012 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/13846/1/An%20improved%20artificial%20neural%20network%20based%20model%20for%20prediction%20of%20late%20onset%20heart%20failure.pdf Salari, Nader and Shohaimi, Shamarina and Najafi, Farid and Nallappan, Meenakshii and Karishnarajah, Isthrinayagy (2012) An improved artificial neural network based model for prediction of late onset heart failure. Life Science Journal, 9 (4). pp. 3684-3689. ISSN 1097-8135; ESSN: 2372-613X http://www.lifesciencesite.com/lsj/life0904/ 10.7537/marslsj090412.546
spellingShingle Salari, Nader
Shohaimi, Shamarina
Najafi, Farid
Nallappan, Meenakshii
Karishnarajah, Isthrinayagy
An improved artificial neural network based model for prediction of late onset heart failure
title An improved artificial neural network based model for prediction of late onset heart failure
title_full An improved artificial neural network based model for prediction of late onset heart failure
title_fullStr An improved artificial neural network based model for prediction of late onset heart failure
title_full_unstemmed An improved artificial neural network based model for prediction of late onset heart failure
title_short An improved artificial neural network based model for prediction of late onset heart failure
title_sort improved artificial neural network based model for prediction of late onset heart failure
url http://psasir.upm.edu.my/id/eprint/13846/
http://psasir.upm.edu.my/id/eprint/13846/
http://psasir.upm.edu.my/id/eprint/13846/
http://psasir.upm.edu.my/id/eprint/13846/1/An%20improved%20artificial%20neural%20network%20based%20model%20for%20prediction%20of%20late%20onset%20heart%20failure.pdf