Crystal structure, DNA binding studies, nucleolytic property and topoisomerase I inhibition of zinc complex with 1,10-phenanthroline and 3 methyl-picolinic acid
Crystal structure analysis of the zinc complex establishes it as a distorted octahedral complex, bis(3-methylpicolinato-κ2 N,O)2(1,10-phenanthroline-κ2 N,N)-zinc(II) pentahydrate, [Zn(3-Me-pic)2(phen)]·5H2O. The trans-configuration of carbonyl oxygen atoms of the carboxylate moieties and orientation...
| Main Authors: | Seng, Hoi Ling, Von, Sze Tin, Tan, Kong Wai, Maah, Mohd Jamil, Ng, Seik Weng, Raja Abdul Rahman, Raja Noor Zaliha, Caracelli, Ignez, Ng, Chew Hee |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2010
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/13835/ http://psasir.upm.edu.my/id/eprint/13835/1/Crystal%20structure%2C%20DNA%20binding%20studies%2C%20nucleolytic%20property%20and%20topoisomerase%20I%20inhibition%20of%20zinc%20complex%20with%201%2C10-phenanthroline%20and%203%20methyl-picolinic%20acid.pdf |
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