Prevalence of left ventricular diastolic dysfunction among hypertensive adults in Klang Valley, Malaysia

A large number of patients with heart failure suffer from Left Ventricular Diastolic Dysfunction (LVDD), but little is known about its prevalence among hypertensive adults, especially in the primary care setting. Thus, this quantitative study aims to evaluate the prevalence and factors associated wi...

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Main Authors: Ching, Siew Mooi, Chia, Yook Chin, Wan Ahmad, Wan Azman, Jalalian, Mehrdad
Format: Article
Language:English
Published: Marsland Press 2012
Online Access:http://psasir.upm.edu.my/id/eprint/13824/
http://psasir.upm.edu.my/id/eprint/13824/1/Prevalence%20of%20left%20ventricular%20diastolic%20dysfunction%20among%20hypertensive%20adults%20in%20Klang%20Valley%2C%20Malaysia.pdf
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author Ching, Siew Mooi
Chia, Yook Chin
Wan Ahmad, Wan Azman
Jalalian, Mehrdad
author_facet Ching, Siew Mooi
Chia, Yook Chin
Wan Ahmad, Wan Azman
Jalalian, Mehrdad
author_sort Ching, Siew Mooi
building UPM Institutional Repository
collection Online Access
description A large number of patients with heart failure suffer from Left Ventricular Diastolic Dysfunction (LVDD), but little is known about its prevalence among hypertensive adults, especially in the primary care setting. Thus, this quantitative study aims to evaluate the prevalence and factors associated with LVDD. A cross-sectional study was conducted among 359 hypertensive patients who underwent echocardiography tests to define their cardiac structure and function. The ratio peak of early to late diastolic filling velocity was used to assess the LVDD. The Framingham risk score was derived from the most recent blood test available in the previous year. SPSS version 19 was used to analyze the data. Echocardiography LVDD was found in 68% of the participants. Of the 243 hypertensive subjects who had LVDD, 69.5% had no left ventricular hypertrophy (LVH) while 30.5% had LVH. Age (odds ratio (OR) 1.11, 95% confidence interval (CI) 1.07-1.15), fasting blood sugar (OR 1.18, 95% CI 1.02-1.37), poor blood pressure control (OR 1.93, 95% CI 1.12-3.32), central obesity (OR 2.06, 95% CI 1.17-3.64), and LVH (OR 2.76, 95% CI 1.29- 5.90) were found to have a significant positive relation with LVDD. Poor hypertension control, diabetes, older age, central obesity, and LVH are the predictors for the development of diastolic dysfunction.
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spelling upm-138242018-08-14T08:42:30Z http://psasir.upm.edu.my/id/eprint/13824/ Prevalence of left ventricular diastolic dysfunction among hypertensive adults in Klang Valley, Malaysia Ching, Siew Mooi Chia, Yook Chin Wan Ahmad, Wan Azman Jalalian, Mehrdad A large number of patients with heart failure suffer from Left Ventricular Diastolic Dysfunction (LVDD), but little is known about its prevalence among hypertensive adults, especially in the primary care setting. Thus, this quantitative study aims to evaluate the prevalence and factors associated with LVDD. A cross-sectional study was conducted among 359 hypertensive patients who underwent echocardiography tests to define their cardiac structure and function. The ratio peak of early to late diastolic filling velocity was used to assess the LVDD. The Framingham risk score was derived from the most recent blood test available in the previous year. SPSS version 19 was used to analyze the data. Echocardiography LVDD was found in 68% of the participants. Of the 243 hypertensive subjects who had LVDD, 69.5% had no left ventricular hypertrophy (LVH) while 30.5% had LVH. Age (odds ratio (OR) 1.11, 95% confidence interval (CI) 1.07-1.15), fasting blood sugar (OR 1.18, 95% CI 1.02-1.37), poor blood pressure control (OR 1.93, 95% CI 1.12-3.32), central obesity (OR 2.06, 95% CI 1.17-3.64), and LVH (OR 2.76, 95% CI 1.29- 5.90) were found to have a significant positive relation with LVDD. Poor hypertension control, diabetes, older age, central obesity, and LVH are the predictors for the development of diastolic dysfunction. Marsland Press 2012 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/13824/1/Prevalence%20of%20left%20ventricular%20diastolic%20dysfunction%20among%20hypertensive%20adults%20in%20Klang%20Valley%2C%20Malaysia.pdf Ching, Siew Mooi and Chia, Yook Chin and Wan Ahmad, Wan Azman and Jalalian, Mehrdad (2012) Prevalence of left ventricular diastolic dysfunction among hypertensive adults in Klang Valley, Malaysia. Life Science Journal, 9 (3). pp. 713-719. ISSN 1097-8135; ESSN: 2372-613X http://www.lifesciencesite.com/lsj/life0903/ 10.7537/marslsj090312.100
spellingShingle Ching, Siew Mooi
Chia, Yook Chin
Wan Ahmad, Wan Azman
Jalalian, Mehrdad
Prevalence of left ventricular diastolic dysfunction among hypertensive adults in Klang Valley, Malaysia
title Prevalence of left ventricular diastolic dysfunction among hypertensive adults in Klang Valley, Malaysia
title_full Prevalence of left ventricular diastolic dysfunction among hypertensive adults in Klang Valley, Malaysia
title_fullStr Prevalence of left ventricular diastolic dysfunction among hypertensive adults in Klang Valley, Malaysia
title_full_unstemmed Prevalence of left ventricular diastolic dysfunction among hypertensive adults in Klang Valley, Malaysia
title_short Prevalence of left ventricular diastolic dysfunction among hypertensive adults in Klang Valley, Malaysia
title_sort prevalence of left ventricular diastolic dysfunction among hypertensive adults in klang valley, malaysia
url http://psasir.upm.edu.my/id/eprint/13824/
http://psasir.upm.edu.my/id/eprint/13824/
http://psasir.upm.edu.my/id/eprint/13824/
http://psasir.upm.edu.my/id/eprint/13824/1/Prevalence%20of%20left%20ventricular%20diastolic%20dysfunction%20among%20hypertensive%20adults%20in%20Klang%20Valley%2C%20Malaysia.pdf