Chemical constituents and bioactivities of Kaempferia rotunda L.
Phytochemical study on the rhizomes of Kaempferia rotunda originated from Yogyakarta, Indonesia has led to the isolation of crotepoxide, benzoic acid, tetracosanoic acid, b-sitosterol and stigmasterol. Tetracosanoic acid and benzoic acid have never been reported for this species previously. Bioactiv...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English English |
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Ultra Scientist of Physical Sciences
2009
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| Online Access: | http://psasir.upm.edu.my/id/eprint/13570/ http://psasir.upm.edu.my/id/eprint/13570/1/Chemical%20constituents%20and%20bioactivities%20of%20Kaempferia%20rotunda%20L.pdf |
| _version_ | 1848842148447780864 |
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| author | Md. Sukari, Mohd. Aspollah Neoh, Bee Keat Tang, Sook Wah Riyanto, Sugeng Lajis, Md. Nordin Cheng, Gwendoline Lian Ee |
| author_facet | Md. Sukari, Mohd. Aspollah Neoh, Bee Keat Tang, Sook Wah Riyanto, Sugeng Lajis, Md. Nordin Cheng, Gwendoline Lian Ee |
| author_sort | Md. Sukari, Mohd. Aspollah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Phytochemical study on the rhizomes of Kaempferia rotunda originated from Yogyakarta, Indonesia has led to the isolation of crotepoxide, benzoic acid, tetracosanoic acid, b-sitosterol and stigmasterol. Tetracosanoic acid and benzoic acid have never been reported for this species previously. Bioactivity studies on the extracts and isolated compound (crotepoxide) were carried out. Extracts and crotepoxide from K. rotunda were not active against HL-60 (human promyelocytic leukemic) cell line in cytotoxic testing. However, the non-polar extract demonstrated moderate inhibition in antimicrobial assay whereas in FTC antioxidant testing, all extracts exhibited strong activity as compared to vitamin E. |
| first_indexed | 2025-11-15T07:54:31Z |
| format | Article |
| id | upm-13570 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T07:54:31Z |
| publishDate | 2009 |
| publisher | Ultra Scientist of Physical Sciences |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-135702015-10-22T06:04:15Z http://psasir.upm.edu.my/id/eprint/13570/ Chemical constituents and bioactivities of Kaempferia rotunda L. Md. Sukari, Mohd. Aspollah Neoh, Bee Keat Tang, Sook Wah Riyanto, Sugeng Lajis, Md. Nordin Cheng, Gwendoline Lian Ee Phytochemical study on the rhizomes of Kaempferia rotunda originated from Yogyakarta, Indonesia has led to the isolation of crotepoxide, benzoic acid, tetracosanoic acid, b-sitosterol and stigmasterol. Tetracosanoic acid and benzoic acid have never been reported for this species previously. Bioactivity studies on the extracts and isolated compound (crotepoxide) were carried out. Extracts and crotepoxide from K. rotunda were not active against HL-60 (human promyelocytic leukemic) cell line in cytotoxic testing. However, the non-polar extract demonstrated moderate inhibition in antimicrobial assay whereas in FTC antioxidant testing, all extracts exhibited strong activity as compared to vitamin E. Ultra Scientist of Physical Sciences 2009 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/13570/1/Chemical%20constituents%20and%20bioactivities%20of%20Kaempferia%20rotunda%20L.pdf Md. Sukari, Mohd. Aspollah and Neoh, Bee Keat and Tang, Sook Wah and Riyanto, Sugeng and Lajis, Md. Nordin and Cheng, Gwendoline Lian Ee (2009) Chemical constituents and bioactivities of Kaempferia rotunda L. Ultra Scientist of Physical Sciences, 21 (3). pp. 699-706. ISSN 0970-9150 English |
| spellingShingle | Md. Sukari, Mohd. Aspollah Neoh, Bee Keat Tang, Sook Wah Riyanto, Sugeng Lajis, Md. Nordin Cheng, Gwendoline Lian Ee Chemical constituents and bioactivities of Kaempferia rotunda L. |
| title | Chemical constituents and bioactivities of Kaempferia rotunda L. |
| title_full | Chemical constituents and bioactivities of Kaempferia rotunda L. |
| title_fullStr | Chemical constituents and bioactivities of Kaempferia rotunda L. |
| title_full_unstemmed | Chemical constituents and bioactivities of Kaempferia rotunda L. |
| title_short | Chemical constituents and bioactivities of Kaempferia rotunda L. |
| title_sort | chemical constituents and bioactivities of kaempferia rotunda l. |
| url | http://psasir.upm.edu.my/id/eprint/13570/ http://psasir.upm.edu.my/id/eprint/13570/1/Chemical%20constituents%20and%20bioactivities%20of%20Kaempferia%20rotunda%20L.pdf |