Antinociceptive, anti-inflammatory and antipyretic properties of an aqueous extract of Corchorus capsularis leaves in experimental animal models.
The present study was carried out to establish the antinociceptive, anti-inflammatory and antipyretic properties of an aqueous extract of jute plant leaves, Corchorus capsularis L. (Tiliaceae), in experimental animals. The antinociceptive activity was measured using the abdominal constriction, hot p...
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| Format: | Article |
| Language: | English |
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Informa Healthcare
2009
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| Online Access: | http://psasir.upm.edu.my/id/eprint/13176/ http://psasir.upm.edu.my/id/eprint/13176/1/Antinociceptive%2C%20anti-inflammatory%20and%20antipyretic%20properties%20of%20an%20aqueous%20extract%20of%20Corchorus%20capsularis%20leaves%20in%20experimental%20animal%20models..pdf |
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| author | Zakaria, Zainul Amiruddin Kumar, Gunjan Hanan Raden Mohd Nor, Raden Nur Suraya Sulaiman, Mohd Roslan Abdullah, Fatimah Corazon Mat Jais, Abdul Manan Somchit, Muhammad Nazrul Ismail, Maznah |
| author_facet | Zakaria, Zainul Amiruddin Kumar, Gunjan Hanan Raden Mohd Nor, Raden Nur Suraya Sulaiman, Mohd Roslan Abdullah, Fatimah Corazon Mat Jais, Abdul Manan Somchit, Muhammad Nazrul Ismail, Maznah |
| author_sort | Zakaria, Zainul Amiruddin |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The present study was carried out to establish the antinociceptive, anti-inflammatory and antipyretic properties of an aqueous extract of jute plant leaves, Corchorus capsularis L. (Tiliaceae), in experimental animals. The antinociceptive activity was measured using the abdominal constriction, hot plate and formalin tests, while the anti-inflammatory and antipyretic activities were measured using the carrageenan-induced paw edema and brewer's yeast-induced pyrexia tests, respectively. The extract, obtained after 72 h soaking of the air-dried leaves in distilled water, freeze-drying for 72 h and then prepared in dosages of 11.57, 57.85, and 115.7 mg/kg, was administered subcutaneously (10 ml/kg) 30 min prior to subjection to the above mentioned assays. The extract was found to exhibit significant (antinociceptive, anti-inflammatory and anti-pyretic, activities in a dosage-independent manner. In conclusion, the aqueous extract of C. capsularis possesses antinociceptive and antipyretic activities and supports the previous claim of its traditional use to treat various ailments. |
| first_indexed | 2025-11-15T07:52:49Z |
| format | Article |
| id | upm-13176 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T07:52:49Z |
| publishDate | 2009 |
| publisher | Informa Healthcare |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-131762015-11-25T03:28:29Z http://psasir.upm.edu.my/id/eprint/13176/ Antinociceptive, anti-inflammatory and antipyretic properties of an aqueous extract of Corchorus capsularis leaves in experimental animal models. Zakaria, Zainul Amiruddin Kumar, Gunjan Hanan Raden Mohd Nor, Raden Nur Suraya Sulaiman, Mohd Roslan Abdullah, Fatimah Corazon Mat Jais, Abdul Manan Somchit, Muhammad Nazrul Ismail, Maznah The present study was carried out to establish the antinociceptive, anti-inflammatory and antipyretic properties of an aqueous extract of jute plant leaves, Corchorus capsularis L. (Tiliaceae), in experimental animals. The antinociceptive activity was measured using the abdominal constriction, hot plate and formalin tests, while the anti-inflammatory and antipyretic activities were measured using the carrageenan-induced paw edema and brewer's yeast-induced pyrexia tests, respectively. The extract, obtained after 72 h soaking of the air-dried leaves in distilled water, freeze-drying for 72 h and then prepared in dosages of 11.57, 57.85, and 115.7 mg/kg, was administered subcutaneously (10 ml/kg) 30 min prior to subjection to the above mentioned assays. The extract was found to exhibit significant (antinociceptive, anti-inflammatory and anti-pyretic, activities in a dosage-independent manner. In conclusion, the aqueous extract of C. capsularis possesses antinociceptive and antipyretic activities and supports the previous claim of its traditional use to treat various ailments. Informa Healthcare 2009-02 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/13176/1/Antinociceptive%2C%20anti-inflammatory%20and%20antipyretic%20properties%20of%20an%20aqueous%20extract%20of%20Corchorus%20capsularis%20leaves%20in%20experimental%20animal%20models..pdf Zakaria, Zainul Amiruddin and Kumar, Gunjan Hanan and Raden Mohd Nor, Raden Nur Suraya and Sulaiman, Mohd Roslan and Abdullah, Fatimah Corazon and Mat Jais, Abdul Manan and Somchit, Muhammad Nazrul and Ismail, Maznah (2009) Antinociceptive, anti-inflammatory and antipyretic properties of an aqueous extract of Corchorus capsularis leaves in experimental animal models. Pharmaceutical Biology, 47 (2). 104 - 110. ISSN 1388-0209; ESSN: 1744-5116 http://informahealthcare.com/doi/abs/10.1080/13880200802436539 10.1080/13880200802436539 |
| spellingShingle | Zakaria, Zainul Amiruddin Kumar, Gunjan Hanan Raden Mohd Nor, Raden Nur Suraya Sulaiman, Mohd Roslan Abdullah, Fatimah Corazon Mat Jais, Abdul Manan Somchit, Muhammad Nazrul Ismail, Maznah Antinociceptive, anti-inflammatory and antipyretic properties of an aqueous extract of Corchorus capsularis leaves in experimental animal models. |
| title | Antinociceptive, anti-inflammatory and antipyretic properties of an aqueous extract of Corchorus capsularis leaves in experimental animal models. |
| title_full | Antinociceptive, anti-inflammatory and antipyretic properties of an aqueous extract of Corchorus capsularis leaves in experimental animal models. |
| title_fullStr | Antinociceptive, anti-inflammatory and antipyretic properties of an aqueous extract of Corchorus capsularis leaves in experimental animal models. |
| title_full_unstemmed | Antinociceptive, anti-inflammatory and antipyretic properties of an aqueous extract of Corchorus capsularis leaves in experimental animal models. |
| title_short | Antinociceptive, anti-inflammatory and antipyretic properties of an aqueous extract of Corchorus capsularis leaves in experimental animal models. |
| title_sort | antinociceptive, anti-inflammatory and antipyretic properties of an aqueous extract of corchorus capsularis leaves in experimental animal models. |
| url | http://psasir.upm.edu.my/id/eprint/13176/ http://psasir.upm.edu.my/id/eprint/13176/ http://psasir.upm.edu.my/id/eprint/13176/ http://psasir.upm.edu.my/id/eprint/13176/1/Antinociceptive%2C%20anti-inflammatory%20and%20antipyretic%20properties%20of%20an%20aqueous%20extract%20of%20Corchorus%20capsularis%20leaves%20in%20experimental%20animal%20models..pdf |