Antinociceptive activity of a synthetic chalcone, flavokawin B on chemical and thermal models of nociception in mice

QR Code

Antinociceptive activity of a synthetic chalcone, flavokawin B on chemical and thermal models of nociception in mice

The present study examined the potential antinociceptive activity of flavokawin B (6'-hydroxy-2',4'-dimethoxychalcone), a synthetic chalcone using chemical- and thermal-induced nociception models in mice. It was demonstrated that flavokawin B (FKB; 0.3, 1, 3 and 10 mg/kg) administered...

Full description

Bibliographic Details
Main Authors:	Tengku Mohamad, Tengku Azam Shah, Akhtar, Mohamad Nadeem, Zakaria, Zainul Amiruddin, Perimal, Enoch Kumar, Khalid, Syamimi, P. A. Mohd, Khalid, Mohamed Hanief, Israf Ali, Daud Ahmad, Lajis, Md. Nordin, Sulaiman, Mohd Roslan
Format:	Article
Language:	English
Published:	Elsevier 2010
Online Access:	http://psasir.upm.edu.my/id/eprint/13161/ http://psasir.upm.edu.my/id/eprint/13161/1/Antinociceptive%20activity%20of%20a%20synthetic%20chalcone.pdf

Similar Items

Peripheral antinociception of a chalcone, flavokawin B and possible involvement of the nitric oxide/cyclic guanosine monophosphate/potassium channels pathway
by: Kamaldin, Mohd Nasier, et al.
Published: (2013)

Antinociceptive activity of a synthetic curcuminoid analogue, 2,6-bis-(4-hydroxy-3-methoxybenzylidene)cyclohexanone, on nociception-induced models in mice.
by: Lee, Ming Tatt, et al.
Published: (2012)

Peripheral Antinociception of a Chalcone, Flavokawin B and Possible Involvement of the Nitric Oxide/Cyclic Guanosine Monophosphate/Potassium Channels Pathway
by: Akhtar, Muhammad Nadeem, et al.
Published: (2013)

Antinociceptive effect of the essential oil of Zingiber zerumbet in mice : possible mechanisms
by: Khalid, Mohamed Hanief, et al.
Published: (2011)

Possible participation of nitric oxide/cyclic guanosine monophosphate/protein kinase C/ATP-sensitive K + channels pathway in the systemic antinociception of flavokawin B.
by: Tengku Mohamad, Tengku Azam Shah, et al.
Published: (2011)

Antinociceptive Effect of 3-(2,3-Dimethoxyphenyl)-1-(5-methylfuran-2-yl)prop-2-en-1-one in Mice Models of Induced Nociception
by: Nur Izzati, Ismail, et al.
Published: (2016)

Activity of cardamonin on chemical model of nociception in mice
by: Chung, Pui Ping, et al.
Published: (2014)

Antinociceptive effect of 3-(2,3-dimethoxyphenyl)-1-(5-methylfuran-2-yl)prop-2-en-1-one in mice models of induced nociception
by: Ismail, Nur Izzati, et al.
Published: (2016)

Antinociceptive Effects of Cardamonin in Mice: Possible Involvement of TRPV1, Glutamate, and Opioid Receptors
by: Chung, Pui Ping, et al.
Published: (2018)

Antinociceptive effects of cardamonin in mice: Possible involvement of TRPV1, glutamate and opioid receptors
by: Chung, Pui Ping, et al.
Published: (2018)

Antinociceptive activity of methanolic extract of Acmella uliginosa (Sw.) Cass.
by: Ong, Hui Ming, et al.
Published: (2011)

Zerumbone-induced antinociception: involvement of the L-arginine-nitric oxide-cGMP -PKC-K+ ATP channel pathways.
by: Perimal, Enoch Kumar, et al.
Published: (2011)

Anti-inflammatory effect of zerumbone on acute and chronic inflammation models in mice.
by: Sulaiman, Mohd Roslan, et al.
Published: (2010)

Antinociceptive activity of asiaticoside in mouse models of induced nociception
by: Ayumi, Rasyidah Ryta, et al.
Published: (2020)

Preliminary analysis of the antinociceptive activity of zerumbone
by: Sulaiman, Mohd Roslan, et al.
Published: (2009)

Antinociceptive activity of Asiaticoside in mouse models of induced nociception
by: Mohammad Rasol, Rasyidah Ryta Ayumi, et al.
Published: (2020)

Inhibition of epithelial CC-family chemokine synthesis by the synthetic chalcone DMPF-1 via disruption of NF-κB nuclear translocation and suppression of experimental asthma in mice
by: Rajajendram, Revathee, et al.
Published: (2015)

Involvement of opioid receptors in Boesenbergia pandurata's esssential oil (BPEO)-induced antinociceptive activity in animal model of nociception
by: Makhtar, Nor 'Adilah, et al.
Published: (2012)

Preliminary study on antinociceptove effect of aqueous extract of Boesenbergia pandurata in formalin-induced nociception test in mice
by: Ee, Ai Chin, et al.
Published: (2014)

In vivo anti-nociceptive and anti-inflammatory activities of the aqueous extract of the leaves of Piper sarmentosum.
by: Zakaria, Zainul Amiruddin, et al.
Published: (2010)

Possible Antinociceptive Mechanism and Site of Activity of Haruan (Channa Striatus) Crude Aqueous Extract in Mice
by: Zakaria, Zainul Amiruddin
Published: (2005)

Antinociceptive activity of the essential oil of Zingiber zerumbet.
by: Sulaiman, Mohd Roslan, et al.
Published: (2010)

Participation of Large Ca2+ Activated Potassium Channel in Antinociceptive Activity of Chalcone Derivative (3-(2, 5-dimethoxyphenyl)-1-(5-methylfuran-2-yl) prop-2-en-1-one) DMPF-1 Action in Mice Model
by: Akhtar, Muhammad Nadeem, et al.
Published: (2013)

Evaluation of antinociceptive profile of chalcone derivative (3-(2,5-dimethoxyphenyl)-1-(5- methylfuran-2-yl) prop-2-en-1-one (DMPF-1) in vivo
by: Noor Azlina, Abu Bakar, et al.
Published: (2020)

Evaluation of the antinociceptive activity of Ficus deltoidea aqueous extract.
by: Sulaiman, Mohd Roslan, et al.
Published: (2008)

Possible participation of ionotropic glutamate receptors and L-arginine-nitric oxide-cyclic guanosine monophosphate-ATP-sensitive K+ channel pathway in the antinociceptive activity of cardamonin in acute pain animal models
by: Chung, Pui Ping, et al.
Published: (2020)

Possible participation of ionotropic glutamate receptors and l-arginine-nitric oxide-cyclic guanosine monophosphate-ATP-Sensitive K+ channel pathway in the antinociceptive activity of cardamonin in acute pain animal models
by: Chung, Pui Ping, et al.
Published: (2020)

Antinociceptive and Anti-Inflammatory Activities of Zerumbone from Zingiber Zerumbet (l.) Roscoe ex sm., and its Possible Mechanisms of Action
by: Perimal, Enoch Kumar
Published: (2012)

Antinociceptive activity of Melicope ptelefolia ethanolic extract in experimental animals.
by: Sulaiman, Mohd Roslan, et al.
Published: (2010)

Antinociceptive profile of a synthetic curcuminoid derivative, 2,6-bis-4-(hydroxy-3-methoxy-benzilidine)-cyclohexanone in murine model of induced-nociception
by: Lee, Ming Tatt
Published: (2013)

Antiinflammatory and antinociceptive activities of Zingiber zerumbet methanol extract in experimental model systems
by: Zakaria, Zainul Amiruddin, et al.
Published: (2010)

Antinociceptive and anti-inflammatory effects of stachytarpheta jamaicensis (L.) Vahl (Verbenaceae)in experimental animal models.
by: Sulaiman, Mohd Roslan, et al.
Published: (2009)

Antinociceptive activity of Melicope ptefolia ethanolic extract in experimental animals
by: Sulaiman, Mohd Roslan, et al.
Published: (2010)

Antinociceptive and anti-inflammatory effects of the ethanol extract of Alpinia conchigera rhizomes in various animal models.
by: Sulaiman, Mohd Roslan, et al.
Published: (2010)

Anti-inflammatory and antinociceptive effects of Mitragyna speciosa Korth methanolic extract.
by: Shaik Mossadeq, Wan Mastura, et al.
Published: (2009)

Antinociceptive and antiedematogenic activities of andrographolide isolated from Andrographis paniculata in animal models.
by: Sulaiman, Mohd Roslan, et al.
Published: (2010)

Antinociceptive activity of Channa striatus (haruan) extracts in mice
by: Mat Jais, Abdul Manan, et al.
Published: (1997)

Antinociceptive activities of a novel diarylpentanoid analogue, 2-benzoyl-6-(3-bromo-4-hydroxybenzylidene)cyclohexen-1-ol, and its possible mechanisms of action in mice
by: Ong, Hui Ming, et al.
Published: (2021)

Antinociceptive effects of alkaloids rich fraction of aidia densiflora in mice
by: Soib, Husnul Hanani, et al.
Published: (2014)

Antinociceptive effect of Momordica charantia flesh aqueous extract in mice
by: Yusob, Siti Aminah, et al.
Published: (2012)