Anti-inflammatory and antinociceptive activities of the ethanolic extract of Pluchea indica (L) less leaf
Ethanolic extract of Pluchea indica leaf (PIL) was used to investigate its anti-inflammatory and antinociceptive activities by using carrageenan - induced oedema model and acetic acid induced writhing test. PIL exhibited significant and dose-dependent anti-inflammatory activity at a dose of 300 mg/k...
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| Format: | Article |
| Language: | English |
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Società Italo-Latinoamericana di Etnomedicina
2008
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| Online Access: | http://psasir.upm.edu.my/id/eprint/13149/ http://psasir.upm.edu.my/id/eprint/13149/1/Anti-inflammatory%20and%20antinociceptive%20activities%20of%20the%20ethanolic%20extract%20of%20Pluchea%20indica%20%28L%29%20less%20leaf.pdf |
| _version_ | 1848842032862199808 |
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| author | Abd Hamid @ Abdul Razak, Roslida A. K., Erazuliana Ahmad, Zuraini |
| author_facet | Abd Hamid @ Abdul Razak, Roslida A. K., Erazuliana Ahmad, Zuraini |
| author_sort | Abd Hamid @ Abdul Razak, Roslida |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Ethanolic extract of Pluchea indica leaf (PIL) was used to investigate its anti-inflammatory and antinociceptive activities by using carrageenan - induced oedema model and acetic acid induced writhing test. PIL exhibited significant and dose-dependent anti-inflammatory activity at a dose of 300 mg/kg when administered orally. It is also demonstrated that the i.p administration of PIL at a dose of 10, 30, 100 and 300 mg/kg produced significant inhibition of abdominal constriction induced with 0.6% (v/v) acetic acid in dose dependent manner. These results indicate that PIL exhibits significant anti-inflammatory and antinociceptive effects. |
| first_indexed | 2025-11-15T07:52:41Z |
| format | Article |
| id | upm-13149 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T07:52:41Z |
| publishDate | 2008 |
| publisher | Società Italo-Latinoamericana di Etnomedicina |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-131492016-10-31T01:53:48Z http://psasir.upm.edu.my/id/eprint/13149/ Anti-inflammatory and antinociceptive activities of the ethanolic extract of Pluchea indica (L) less leaf Abd Hamid @ Abdul Razak, Roslida A. K., Erazuliana Ahmad, Zuraini Ethanolic extract of Pluchea indica leaf (PIL) was used to investigate its anti-inflammatory and antinociceptive activities by using carrageenan - induced oedema model and acetic acid induced writhing test. PIL exhibited significant and dose-dependent anti-inflammatory activity at a dose of 300 mg/kg when administered orally. It is also demonstrated that the i.p administration of PIL at a dose of 10, 30, 100 and 300 mg/kg produced significant inhibition of abdominal constriction induced with 0.6% (v/v) acetic acid in dose dependent manner. These results indicate that PIL exhibits significant anti-inflammatory and antinociceptive effects. Società Italo-Latinoamericana di Etnomedicina 2008 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/13149/1/Anti-inflammatory%20and%20antinociceptive%20activities%20of%20the%20ethanolic%20extract%20of%20Pluchea%20indica%20%28L%29%20less%20leaf.pdf Abd Hamid @ Abdul Razak, Roslida and A. K., Erazuliana and Ahmad, Zuraini (2008) Anti-inflammatory and antinociceptive activities of the ethanolic extract of Pluchea indica (L) less leaf. Pharmacologyonline, 2. pp. 349-360. ISSN 1827-8620 http://pharmacologyonline.silae.it/front/archives_2008_2 |
| spellingShingle | Abd Hamid @ Abdul Razak, Roslida A. K., Erazuliana Ahmad, Zuraini Anti-inflammatory and antinociceptive activities of the ethanolic extract of Pluchea indica (L) less leaf |
| title | Anti-inflammatory and antinociceptive activities of the ethanolic extract of Pluchea indica (L) less leaf |
| title_full | Anti-inflammatory and antinociceptive activities of the ethanolic extract of Pluchea indica (L) less leaf |
| title_fullStr | Anti-inflammatory and antinociceptive activities of the ethanolic extract of Pluchea indica (L) less leaf |
| title_full_unstemmed | Anti-inflammatory and antinociceptive activities of the ethanolic extract of Pluchea indica (L) less leaf |
| title_short | Anti-inflammatory and antinociceptive activities of the ethanolic extract of Pluchea indica (L) less leaf |
| title_sort | anti-inflammatory and antinociceptive activities of the ethanolic extract of pluchea indica (l) less leaf |
| url | http://psasir.upm.edu.my/id/eprint/13149/ http://psasir.upm.edu.my/id/eprint/13149/ http://psasir.upm.edu.my/id/eprint/13149/1/Anti-inflammatory%20and%20antinociceptive%20activities%20of%20the%20ethanolic%20extract%20of%20Pluchea%20indica%20%28L%29%20less%20leaf.pdf |