Antifungal properties of Allium sativum extracts on Candida species
Candida albicans, Candida tropicalis and Candida krusei frequently cause many infections in immunodeficient humans. The infection invariably becomes invasive and disseminate to other body sites. Tests of antifungal effect of Azadirachta indica (Neem), Peperomia pellucida (“ketumpang air”) and Allium...
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| Format: | Article |
| Language: | English |
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Total Health Concept Sdn.bhd
2008
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| Online Access: | http://psasir.upm.edu.my/id/eprint/13143/ http://psasir.upm.edu.my/id/eprint/13143/1/Antifungal%20properties%20of%20Allium%20sativum%20extracts%20on%20Candida%20species.pdf |
| _version_ | 1848842031199158272 |
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| author | Low, Chen Fei Yong, Phelim Voon Chen Ahmad, Zuraini Othman, Fauziah Chong, Pei Pei |
| author_facet | Low, Chen Fei Yong, Phelim Voon Chen Ahmad, Zuraini Othman, Fauziah Chong, Pei Pei |
| author_sort | Low, Chen Fei |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Candida albicans, Candida tropicalis and Candida krusei frequently cause many infections in immunodeficient humans. The infection invariably becomes invasive and disseminate to other body sites. Tests of antifungal effect of Azadirachta indica (Neem), Peperomia pellucida (“ketumpang air”) and Allium sativum (Garlic) extracts on the three Candida species through paper disc diffusion method showed that all the three Candida species were resistant to A. indica and P. pellucida, but susceptible to A. sativum extract. Subsequently, the effect of different concentrations of garlic extract on the growth of C. albicans was evaluated to determine the IC50 and LD50. The effect of garlic extract suggests that sublethal doses can reduce the colonization of Candida species in the oral cavity of humans by suppressing the virulent hyphal growth form.
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| first_indexed | 2025-11-15T07:52:40Z |
| format | Article |
| id | upm-13143 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T07:52:40Z |
| publishDate | 2008 |
| publisher | Total Health Concept Sdn.bhd |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-131432015-10-05T07:52:04Z http://psasir.upm.edu.my/id/eprint/13143/ Antifungal properties of Allium sativum extracts on Candida species Low, Chen Fei Yong, Phelim Voon Chen Ahmad, Zuraini Othman, Fauziah Chong, Pei Pei Candida albicans, Candida tropicalis and Candida krusei frequently cause many infections in immunodeficient humans. The infection invariably becomes invasive and disseminate to other body sites. Tests of antifungal effect of Azadirachta indica (Neem), Peperomia pellucida (“ketumpang air”) and Allium sativum (Garlic) extracts on the three Candida species through paper disc diffusion method showed that all the three Candida species were resistant to A. indica and P. pellucida, but susceptible to A. sativum extract. Subsequently, the effect of different concentrations of garlic extract on the growth of C. albicans was evaluated to determine the IC50 and LD50. The effect of garlic extract suggests that sublethal doses can reduce the colonization of Candida species in the oral cavity of humans by suppressing the virulent hyphal growth form. Total Health Concept Sdn.bhd 2008-06 Article NonPeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/13143/1/Antifungal%20properties%20of%20Allium%20sativum%20extracts%20on%20Candida%20species.pdf Low, Chen Fei and Yong, Phelim Voon Chen and Ahmad, Zuraini and Othman, Fauziah and Chong, Pei Pei (2008) Antifungal properties of Allium sativum extracts on Candida species. Journal of Tropical Medicinal Plants, 9 (1). pp. 43-48. ISSN 1511-8525 |
| spellingShingle | Low, Chen Fei Yong, Phelim Voon Chen Ahmad, Zuraini Othman, Fauziah Chong, Pei Pei Antifungal properties of Allium sativum extracts on Candida species |
| title | Antifungal properties of Allium sativum extracts on Candida species |
| title_full | Antifungal properties of Allium sativum extracts on Candida species |
| title_fullStr | Antifungal properties of Allium sativum extracts on Candida species |
| title_full_unstemmed | Antifungal properties of Allium sativum extracts on Candida species |
| title_short | Antifungal properties of Allium sativum extracts on Candida species |
| title_sort | antifungal properties of allium sativum extracts on candida species |
| url | http://psasir.upm.edu.my/id/eprint/13143/ http://psasir.upm.edu.my/id/eprint/13143/1/Antifungal%20properties%20of%20Allium%20sativum%20extracts%20on%20Candida%20species.pdf |