Antibacterial effect of Gracilaria changii and Euchema denticulatum on molecular properties of Staphylococcus aureus genes mecA, mecR1 and mecl
Gram-positive bacteria are more sensitive to antibiotics than gram-negative bacilli because of the lack of outer membrane which prevent easy access of the drug into the bacterial cells. However, there are many gram-positive organisms with natural, intrinsic resistance to antimicrobials. In addition,...
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| Format: | Article |
| Language: | English |
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Medwell Journals
2009
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| Online Access: | http://psasir.upm.edu.my/id/eprint/13134/ http://psasir.upm.edu.my/id/eprint/13134/1/Antibacterial%20effect%20of%20Gracilaria%20changii%20and%20Euchema%20denticulatum%20on%20molecular%20properties%20of%20Staphylococcus%20aureus%20genes%20mecA.pdf |
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| author | Al-Haj, Nagi Ahmed Mashan, Nurmas Izaty Shamsudin , Mariana Nor Mohamad, Habsah Vairappan, Charles S. Sekawi, Zamberi |
| author_facet | Al-Haj, Nagi Ahmed Mashan, Nurmas Izaty Shamsudin , Mariana Nor Mohamad, Habsah Vairappan, Charles S. Sekawi, Zamberi |
| author_sort | Al-Haj, Nagi Ahmed |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Gram-positive bacteria are more sensitive to antibiotics than gram-negative bacilli because of the lack of outer membrane which prevent easy access of the drug into the bacterial cells. However, there are many gram-positive organisms with natural, intrinsic resistance to antimicrobials. In addition, these bacteria are able to acquire resistance to frequently used drugs rapidly through selective pressure of the environment and also via the genetic evolution of bacteria. The resistance of those bacteria to antibacterial agents is mediated by antibiotic resistant genes. Therefore, the current study was designed to explore the effect of seaweed extracts on several antibiotic resistant genes in Staphylococcus aureus mec genes mecA, mecR1 and mecI that regulate the expression of methicillin resistance was investigated by PCR. |
| first_indexed | 2025-11-15T07:52:37Z |
| format | Article |
| id | upm-13134 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T07:52:37Z |
| publishDate | 2009 |
| publisher | Medwell Journals |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-131342015-11-19T07:33:56Z http://psasir.upm.edu.my/id/eprint/13134/ Antibacterial effect of Gracilaria changii and Euchema denticulatum on molecular properties of Staphylococcus aureus genes mecA, mecR1 and mecl Al-Haj, Nagi Ahmed Mashan, Nurmas Izaty Shamsudin , Mariana Nor Mohamad, Habsah Vairappan, Charles S. Sekawi, Zamberi Gram-positive bacteria are more sensitive to antibiotics than gram-negative bacilli because of the lack of outer membrane which prevent easy access of the drug into the bacterial cells. However, there are many gram-positive organisms with natural, intrinsic resistance to antimicrobials. In addition, these bacteria are able to acquire resistance to frequently used drugs rapidly through selective pressure of the environment and also via the genetic evolution of bacteria. The resistance of those bacteria to antibacterial agents is mediated by antibiotic resistant genes. Therefore, the current study was designed to explore the effect of seaweed extracts on several antibiotic resistant genes in Staphylococcus aureus mec genes mecA, mecR1 and mecI that regulate the expression of methicillin resistance was investigated by PCR. Medwell Journals 2009 Article NonPeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/13134/1/Antibacterial%20effect%20of%20Gracilaria%20changii%20and%20Euchema%20denticulatum%20on%20molecular%20properties%20of%20Staphylococcus%20aureus%20genes%20mecA.pdf Al-Haj, Nagi Ahmed and Mashan, Nurmas Izaty and Shamsudin , Mariana Nor and Mohamad, Habsah and Vairappan, Charles S. and Sekawi, Zamberi (2009) Antibacterial effect of Gracilaria changii and Euchema denticulatum on molecular properties of Staphylococcus aureus genes mecA, mecR1 and mecl. Research Journal of Biological Sciences, 4 (5). pp. 580-584. ISSN 1815-8846; ESSN: 1993-6087 http://www.medwelljournals.com/fulltext/?doi=rjbsci.2009.580.584 |
| spellingShingle | Al-Haj, Nagi Ahmed Mashan, Nurmas Izaty Shamsudin , Mariana Nor Mohamad, Habsah Vairappan, Charles S. Sekawi, Zamberi Antibacterial effect of Gracilaria changii and Euchema denticulatum on molecular properties of Staphylococcus aureus genes mecA, mecR1 and mecl |
| title | Antibacterial effect of Gracilaria changii and Euchema denticulatum on molecular properties of Staphylococcus aureus genes mecA, mecR1 and mecl |
| title_full | Antibacterial effect of Gracilaria changii and Euchema denticulatum on molecular properties of Staphylococcus aureus genes mecA, mecR1 and mecl |
| title_fullStr | Antibacterial effect of Gracilaria changii and Euchema denticulatum on molecular properties of Staphylococcus aureus genes mecA, mecR1 and mecl |
| title_full_unstemmed | Antibacterial effect of Gracilaria changii and Euchema denticulatum on molecular properties of Staphylococcus aureus genes mecA, mecR1 and mecl |
| title_short | Antibacterial effect of Gracilaria changii and Euchema denticulatum on molecular properties of Staphylococcus aureus genes mecA, mecR1 and mecl |
| title_sort | antibacterial effect of gracilaria changii and euchema denticulatum on molecular properties of staphylococcus aureus genes meca, mecr1 and mecl |
| url | http://psasir.upm.edu.my/id/eprint/13134/ http://psasir.upm.edu.my/id/eprint/13134/ http://psasir.upm.edu.my/id/eprint/13134/1/Antibacterial%20effect%20of%20Gracilaria%20changii%20and%20Euchema%20denticulatum%20on%20molecular%20properties%20of%20Staphylococcus%20aureus%20genes%20mecA.pdf |