Andrographolide inhibits growth of acute promyelocytic leukaemia cells by inducing retinoic acid receptor-independent cell differentiation and apoptosis

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Andrographolide inhibits growth of acute promyelocytic leukaemia cells by inducing retinoic acid receptor-independent cell differentiation and apoptosis

OBJECTIVES: The growth inhibiting potential of andrographolide was evaluated in three acute promyelocytic leukaemia cell line models (HL-60, NB4 and all-trans retinoic acid (ATRA)-resistant NB4-R2). METHODS: In elucidating the mechanisms of growth inhibition, a special emphasis was placed on assess...

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Bibliographic Details
Main Authors:	Manikam, Shiamala Devi, Stanslas, Johnson
Format:	Article
Language:	English
Published:	John Wiley & Sons 2009
Online Access:	http://psasir.upm.edu.my/id/eprint/13109/ http://psasir.upm.edu.my/id/eprint/13109/1/Andrographolide%20inhibits%20growth%20of%20acute%20promyelocytic%20leukaemia%20cells%20by%20inducing%20retinoic%20acid%20receptor.pdf

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