Acutaxylines A and B, two novel triterpenes from Dysoxylum acutangulum
Two novel triterpenes, acutaxylines A (1) and B (2) consisting of a cyclopentenone side chain at C-17 and an oxepan-2-ol, were isolated from the leaves of Dysoxylum acutangulum. The relative stereochemistry of 1 and 2 was determined by NOESY correlations. Acutaxyline B showed moderate cytotoxicity a...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Pergamon Press
2009
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/12927/ http://psasir.upm.edu.my/id/eprint/12927/1/Acutaxylines%20A%20and%20B.pdf |
| _version_ | 1848841970478219264 |
|---|---|
| author | Ismail, Intan Safinar Nagakura, Yuta Hirasawa, Yusuke Hosoya, Takahiro Mohd Lazim, Mohd Izwan Lajis, Md. Nordin Morita, Hiroshi |
| author_facet | Ismail, Intan Safinar Nagakura, Yuta Hirasawa, Yusuke Hosoya, Takahiro Mohd Lazim, Mohd Izwan Lajis, Md. Nordin Morita, Hiroshi |
| author_sort | Ismail, Intan Safinar |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Two novel triterpenes, acutaxylines A (1) and B (2) consisting of a cyclopentenone side chain at C-17 and an oxepan-2-ol, were isolated from the leaves of Dysoxylum acutangulum. The relative stereochemistry of 1 and 2 was determined by NOESY correlations. Acutaxyline B showed moderate cytotoxicity against human blood premyelocytic leukemia cells. |
| first_indexed | 2025-11-15T07:51:42Z |
| format | Article |
| id | upm-12927 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T07:51:42Z |
| publishDate | 2009 |
| publisher | Pergamon Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-129272015-09-29T02:57:03Z http://psasir.upm.edu.my/id/eprint/12927/ Acutaxylines A and B, two novel triterpenes from Dysoxylum acutangulum Ismail, Intan Safinar Nagakura, Yuta Hirasawa, Yusuke Hosoya, Takahiro Mohd Lazim, Mohd Izwan Lajis, Md. Nordin Morita, Hiroshi Two novel triterpenes, acutaxylines A (1) and B (2) consisting of a cyclopentenone side chain at C-17 and an oxepan-2-ol, were isolated from the leaves of Dysoxylum acutangulum. The relative stereochemistry of 1 and 2 was determined by NOESY correlations. Acutaxyline B showed moderate cytotoxicity against human blood premyelocytic leukemia cells. Pergamon Press 2009-08-26 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/12927/1/Acutaxylines%20A%20and%20B.pdf Ismail, Intan Safinar and Nagakura, Yuta and Hirasawa, Yusuke and Hosoya, Takahiro and Mohd Lazim, Mohd Izwan and Lajis, Md. Nordin and Morita, Hiroshi (2009) Acutaxylines A and B, two novel triterpenes from Dysoxylum acutangulum. Tetrahedron Letters, 50 (34). pp. 4830-4832. ISSN 0040-4039; ESSN: 1873-3581 10.1016/j.tetlet.2009.05.110 |
| spellingShingle | Ismail, Intan Safinar Nagakura, Yuta Hirasawa, Yusuke Hosoya, Takahiro Mohd Lazim, Mohd Izwan Lajis, Md. Nordin Morita, Hiroshi Acutaxylines A and B, two novel triterpenes from Dysoxylum acutangulum |
| title | Acutaxylines A and B, two novel triterpenes from Dysoxylum acutangulum |
| title_full | Acutaxylines A and B, two novel triterpenes from Dysoxylum acutangulum |
| title_fullStr | Acutaxylines A and B, two novel triterpenes from Dysoxylum acutangulum |
| title_full_unstemmed | Acutaxylines A and B, two novel triterpenes from Dysoxylum acutangulum |
| title_short | Acutaxylines A and B, two novel triterpenes from Dysoxylum acutangulum |
| title_sort | acutaxylines a and b, two novel triterpenes from dysoxylum acutangulum |
| url | http://psasir.upm.edu.my/id/eprint/12927/ http://psasir.upm.edu.my/id/eprint/12927/ http://psasir.upm.edu.my/id/eprint/12927/1/Acutaxylines%20A%20and%20B.pdf |