Acutaxylines A and B, two novel triterpenes from Dysoxylum acutangulum
Two novel triterpenes, acutaxylines A (1) and B (2) consisting of a cyclopentenone side chain at C-17 and an oxepan-2-ol, were isolated from the leaves of Dysoxylum acutangulum. The relative stereochemistry of 1 and 2 was determined by NOESY correlations. Acutaxyline B showed moderate cytotoxicity a...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Pergamon Press
2009
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| Online Access: | http://psasir.upm.edu.my/id/eprint/12927/ http://psasir.upm.edu.my/id/eprint/12927/1/Acutaxylines%20A%20and%20B.pdf |
| Summary: | Two novel triterpenes, acutaxylines A (1) and B (2) consisting of a cyclopentenone side chain at C-17 and an oxepan-2-ol, were isolated from the leaves of Dysoxylum acutangulum. The relative stereochemistry of 1 and 2 was determined by NOESY correlations. Acutaxyline B showed moderate cytotoxicity against human blood premyelocytic leukemia cells. |
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