A rare case of alpha-thalassaemia intermedia in a Malay patient double heterozygous for α+ –thalassaemia and a mutation in α1 globin gene CD59 (GGC → GAC)
A rare case of thalassaemia-intermedia involving a non-deletion alpha thalassemia point mutation in the α1-globin gene CD59 (GGC → GAC) and a deletion α+ (-α3.7) thalassaemia in which use of high performance liquid chromatography (HPLC) C-gram Hb subtype profile and DNA molecular analysis helped est...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Malaysian Medical Association
2009
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| Online Access: | http://psasir.upm.edu.my/id/eprint/12806/ http://psasir.upm.edu.my/id/eprint/12806/1/A%20rare%20case%20of%20alpha-thalassaemia%20intermedia%20in%20a%20Malay%20patient%20double%20heterozygous%20for%20%CE%B1%2B%20%E2%80%93thalassaemia%20and%20a%20mutation%20in%20%CE%B11%20globin%20gene%20CD59%20%28GGC%20%E2%86%92%20GAC%29.pdf |
| _version_ | 1848841935940222976 |
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| author | George, Elizabeth Tan, Mary Anne Jin Ai A. S., Nor Azian Ahmad, Rahimah Zakaria, Zubaidah |
| author_facet | George, Elizabeth Tan, Mary Anne Jin Ai A. S., Nor Azian Ahmad, Rahimah Zakaria, Zubaidah |
| author_sort | George, Elizabeth |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | A rare case of thalassaemia-intermedia involving a non-deletion alpha thalassemia point mutation in the α1-globin gene CD59 (GGC → GAC) and a deletion α+ (-α3.7) thalassaemia in which use of high performance liquid chromatography (HPLC) C-gram Hb subtype profile and DNA molecular analysis helped establish the diagnosis. |
| first_indexed | 2025-11-15T07:51:09Z |
| format | Article |
| id | upm-12806 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T07:51:09Z |
| publishDate | 2009 |
| publisher | Malaysian Medical Association |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-128062016-11-30T03:07:22Z http://psasir.upm.edu.my/id/eprint/12806/ A rare case of alpha-thalassaemia intermedia in a Malay patient double heterozygous for α+ –thalassaemia and a mutation in α1 globin gene CD59 (GGC → GAC) George, Elizabeth Tan, Mary Anne Jin Ai A. S., Nor Azian Ahmad, Rahimah Zakaria, Zubaidah A rare case of thalassaemia-intermedia involving a non-deletion alpha thalassemia point mutation in the α1-globin gene CD59 (GGC → GAC) and a deletion α+ (-α3.7) thalassaemia in which use of high performance liquid chromatography (HPLC) C-gram Hb subtype profile and DNA molecular analysis helped establish the diagnosis. Malaysian Medical Association 2009-12 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/12806/1/A%20rare%20case%20of%20alpha-thalassaemia%20intermedia%20in%20a%20Malay%20patient%20double%20heterozygous%20for%20%CE%B1%2B%20%E2%80%93thalassaemia%20and%20a%20mutation%20in%20%CE%B11%20globin%20gene%20CD59%20%28GGC%20%E2%86%92%20GAC%29.pdf George, Elizabeth and Tan, Mary Anne Jin Ai and A. S., Nor Azian and Ahmad, Rahimah and Zakaria, Zubaidah (2009) A rare case of alpha-thalassaemia intermedia in a Malay patient double heterozygous for α+ –thalassaemia and a mutation in α1 globin gene CD59 (GGC → GAC). Medical Journal of Malaysia, 64 (4). pp. 321-322. ISSN 0300-5283 http://www.e-mjm.org/2009/v64n4/index.html |
| spellingShingle | George, Elizabeth Tan, Mary Anne Jin Ai A. S., Nor Azian Ahmad, Rahimah Zakaria, Zubaidah A rare case of alpha-thalassaemia intermedia in a Malay patient double heterozygous for α+ –thalassaemia and a mutation in α1 globin gene CD59 (GGC → GAC) |
| title | A rare case of alpha-thalassaemia intermedia in a Malay patient double heterozygous for α+ –thalassaemia and a mutation in α1 globin gene CD59 (GGC → GAC) |
| title_full | A rare case of alpha-thalassaemia intermedia in a Malay patient double heterozygous for α+ –thalassaemia and a mutation in α1 globin gene CD59 (GGC → GAC) |
| title_fullStr | A rare case of alpha-thalassaemia intermedia in a Malay patient double heterozygous for α+ –thalassaemia and a mutation in α1 globin gene CD59 (GGC → GAC) |
| title_full_unstemmed | A rare case of alpha-thalassaemia intermedia in a Malay patient double heterozygous for α+ –thalassaemia and a mutation in α1 globin gene CD59 (GGC → GAC) |
| title_short | A rare case of alpha-thalassaemia intermedia in a Malay patient double heterozygous for α+ –thalassaemia and a mutation in α1 globin gene CD59 (GGC → GAC) |
| title_sort | rare case of alpha-thalassaemia intermedia in a malay patient double heterozygous for α+ –thalassaemia and a mutation in α1 globin gene cd59 (ggc → gac) |
| url | http://psasir.upm.edu.my/id/eprint/12806/ http://psasir.upm.edu.my/id/eprint/12806/ http://psasir.upm.edu.my/id/eprint/12806/1/A%20rare%20case%20of%20alpha-thalassaemia%20intermedia%20in%20a%20Malay%20patient%20double%20heterozygous%20for%20%CE%B1%2B%20%E2%80%93thalassaemia%20and%20a%20mutation%20in%20%CE%B11%20globin%20gene%20CD59%20%28GGC%20%E2%86%92%20GAC%29.pdf |