A potential tocopherol acetate loadaer palm oil ester-in-water nanoemulsions for nanocosmeceuticals
Background: Cosmeceuticals are cosmetic-pharmaceutical hybrids intended to enhance health and beauty of the skin. Nanocosmeceuticals use nano-sized system for the delivery of active ingredients to the targeted cells for better penetration. In this work, nanoemulsion from palm oil esters was develo...
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| Format: | Article |
| Language: | English |
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BioMed Central
2010
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| Online Access: | http://psasir.upm.edu.my/id/eprint/12780/ http://psasir.upm.edu.my/id/eprint/12780/1/A%20potential%20tocopherol%20acetate%20loadaer%20palm%20oil%20ester.pdf |
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| author | Teo, Brian Sheng Xian Basri, Mahiran Zakaria, Mohd Rezuwan Shah Salleh, Abu Bakar Raja Abdul Rahman, Raja Noor Zaliha Abdul Rahman, Mohd Basyaruddin |
| author_facet | Teo, Brian Sheng Xian Basri, Mahiran Zakaria, Mohd Rezuwan Shah Salleh, Abu Bakar Raja Abdul Rahman, Raja Noor Zaliha Abdul Rahman, Mohd Basyaruddin |
| author_sort | Teo, Brian Sheng Xian |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Background: Cosmeceuticals are cosmetic-pharmaceutical hybrids intended to enhance health and beauty of the
skin. Nanocosmeceuticals use nano-sized system for the delivery of active ingredients to the targeted cells for
better penetration. In this work, nanoemulsion from palm oil esters was developed as a delivery system to produce
nanocosmeceuticals. The stability of the resulting formulation was tested using various methods. In addition, the effect of components i.e. Vitamin E and Pluronic F-68 on the formulation was also studied. Results: Both vitamin E and Pluronic F-68 were found to co-emulsify and co-stabilized the formulations. The best formulation was found to be the one having the composition of 10% Palm Oil Esters (POEs), 10% vitamin E, 24% Tween 80, 2.4% Pluronic F-68 and 53.6% deionised water. Those compositions are considered to be the best as a nanocosmeceutical product due to the small particle size (94.21 nm), low occurrence of Ostwald ripening and stable at different storing temperatures (5, 25 and 45°C) for four weeks. Conclusions:
Palm oil esters-in-water nanoemulsions loaded with vitamin E was successfully formulated and has the potential for the use as nanocosmeceuticals. |
| first_indexed | 2025-11-15T07:51:02Z |
| format | Article |
| id | upm-12780 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T07:51:02Z |
| publishDate | 2010 |
| publisher | BioMed Central |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-127802016-09-26T07:21:12Z http://psasir.upm.edu.my/id/eprint/12780/ A potential tocopherol acetate loadaer palm oil ester-in-water nanoemulsions for nanocosmeceuticals Teo, Brian Sheng Xian Basri, Mahiran Zakaria, Mohd Rezuwan Shah Salleh, Abu Bakar Raja Abdul Rahman, Raja Noor Zaliha Abdul Rahman, Mohd Basyaruddin Background: Cosmeceuticals are cosmetic-pharmaceutical hybrids intended to enhance health and beauty of the skin. Nanocosmeceuticals use nano-sized system for the delivery of active ingredients to the targeted cells for better penetration. In this work, nanoemulsion from palm oil esters was developed as a delivery system to produce nanocosmeceuticals. The stability of the resulting formulation was tested using various methods. In addition, the effect of components i.e. Vitamin E and Pluronic F-68 on the formulation was also studied. Results: Both vitamin E and Pluronic F-68 were found to co-emulsify and co-stabilized the formulations. The best formulation was found to be the one having the composition of 10% Palm Oil Esters (POEs), 10% vitamin E, 24% Tween 80, 2.4% Pluronic F-68 and 53.6% deionised water. Those compositions are considered to be the best as a nanocosmeceutical product due to the small particle size (94.21 nm), low occurrence of Ostwald ripening and stable at different storing temperatures (5, 25 and 45°C) for four weeks. Conclusions: Palm oil esters-in-water nanoemulsions loaded with vitamin E was successfully formulated and has the potential for the use as nanocosmeceuticals. BioMed Central 2010 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/12780/1/A%20potential%20tocopherol%20acetate%20loadaer%20palm%20oil%20ester.pdf Teo, Brian Sheng Xian and Basri, Mahiran and Zakaria, Mohd Rezuwan Shah and Salleh, Abu Bakar and Raja Abdul Rahman, Raja Noor Zaliha and Abdul Rahman, Mohd Basyaruddin (2010) A potential tocopherol acetate loadaer palm oil ester-in-water nanoemulsions for nanocosmeceuticals. Journal of Nanobiotechnology, 8. art. no. 4. pp. 1-11. ISSN 1477-3155 10.1186/1477-3155-8-4 |
| spellingShingle | Teo, Brian Sheng Xian Basri, Mahiran Zakaria, Mohd Rezuwan Shah Salleh, Abu Bakar Raja Abdul Rahman, Raja Noor Zaliha Abdul Rahman, Mohd Basyaruddin A potential tocopherol acetate loadaer palm oil ester-in-water nanoemulsions for nanocosmeceuticals |
| title | A potential tocopherol acetate loadaer palm oil ester-in-water nanoemulsions for nanocosmeceuticals |
| title_full | A potential tocopherol acetate loadaer palm oil ester-in-water nanoemulsions for nanocosmeceuticals |
| title_fullStr | A potential tocopherol acetate loadaer palm oil ester-in-water nanoemulsions for nanocosmeceuticals |
| title_full_unstemmed | A potential tocopherol acetate loadaer palm oil ester-in-water nanoemulsions for nanocosmeceuticals |
| title_short | A potential tocopherol acetate loadaer palm oil ester-in-water nanoemulsions for nanocosmeceuticals |
| title_sort | potential tocopherol acetate loadaer palm oil ester-in-water nanoemulsions for nanocosmeceuticals |
| url | http://psasir.upm.edu.my/id/eprint/12780/ http://psasir.upm.edu.my/id/eprint/12780/ http://psasir.upm.edu.my/id/eprint/12780/1/A%20potential%20tocopherol%20acetate%20loadaer%20palm%20oil%20ester.pdf |