Enzymatic Synthesis of 3-O-Acylbetulinic Acid Derivatives and Prediction of Acylation Using Response Surface Methodology and Artificial Neural Network Analyses

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Enzymatic Synthesis of 3-O-Acylbetulinic Acid Derivatives and Prediction of Acylation Using Response Surface Methodology and Artificial Neural Network Analyses

In this study, 3-O-acyl-betulinic acid derivatives were synthesized by the reaction of betulinic acid with various anhydrides using lipase as a biocatalyst in organic solvents. The reaction between betulinic acid and phthalic anhydride was chosen as the model reaction for optimization studies. Th...

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Bibliographic Details
Main Author:	Moghaddam, Mansour Ghaffari
Format:	Thesis
Language:	English English
Published:	2010
Subjects:	Acids - Analysis Acylation
Online Access:	http://psasir.upm.edu.my/id/eprint/12441/ http://psasir.upm.edu.my/id/eprint/12441/1/FS_2010_26A.pdf

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