Characterisation And Pathogenicity Studies Of Malaysian Isolates Of Avian Pox Virus

Avian pox is one of the important viral diseases in avian species of which, fowl pox is the most common disease and is usually controlled by vaccination. However, in recent years, outbreaks of the disease in vaccinated flocks have been reported. Therefore, it is important to study the local isola...

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Main Author: Sivasothy, Arumugam
Format: Thesis
Language:English
English
Published: 1997
Subjects:
Online Access:http://psasir.upm.edu.my/id/eprint/12326/
http://psasir.upm.edu.my/id/eprint/12326/1/FPV_1997_5_A.pdf
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author Sivasothy, Arumugam
author_facet Sivasothy, Arumugam
author_sort Sivasothy, Arumugam
building UPM Institutional Repository
collection Online Access
description Avian pox is one of the important viral diseases in avian species of which, fowl pox is the most common disease and is usually controlled by vaccination. However, in recent years, outbreaks of the disease in vaccinated flocks have been reported. Therefore, it is important to study the local isolates as well as vaccine strains in order to determine the cause of the outbreaks. This study was conducted to isolate, identify and characterise the field strains of avipox virus, which caused outbreaks among poultry in Malaysia. The isolates were also compared with the vaccine strain (TC-B I2) by pathogenicity studies in chickens. Initial characterisation of isolates involved morphology by electron microscopy, changes in embryonated chicken eggs, inclusion body formation, immunoperoxidase test and cytopathogenicity in cell culture.Five avipox viruses were isolated from chicken, pigeon and turkey. Negative contrast electron microscopy showed the unique morphology of the isolates and did not show an y differentiation among the isolates in respect to their origin. The isolates were titrated in embryonated eggs and the isolates from pigeon and turkey gave lower titre in comparison to other isolates. On chorioallantoic membrane (CAM), mother pock lesions were produced by the isolates from pigeon and turkey in comparison to the isolates from chicken which produced scattered pock lesions.
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institution Universiti Putra Malaysia
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language English
English
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publishDate 1997
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spelling upm-123262011-07-13T01:26:15Z http://psasir.upm.edu.my/id/eprint/12326/ Characterisation And Pathogenicity Studies Of Malaysian Isolates Of Avian Pox Virus Sivasothy, Arumugam Avian pox is one of the important viral diseases in avian species of which, fowl pox is the most common disease and is usually controlled by vaccination. However, in recent years, outbreaks of the disease in vaccinated flocks have been reported. Therefore, it is important to study the local isolates as well as vaccine strains in order to determine the cause of the outbreaks. This study was conducted to isolate, identify and characterise the field strains of avipox virus, which caused outbreaks among poultry in Malaysia. The isolates were also compared with the vaccine strain (TC-B I2) by pathogenicity studies in chickens. Initial characterisation of isolates involved morphology by electron microscopy, changes in embryonated chicken eggs, inclusion body formation, immunoperoxidase test and cytopathogenicity in cell culture.Five avipox viruses were isolated from chicken, pigeon and turkey. Negative contrast electron microscopy showed the unique morphology of the isolates and did not show an y differentiation among the isolates in respect to their origin. The isolates were titrated in embryonated eggs and the isolates from pigeon and turkey gave lower titre in comparison to other isolates. On chorioallantoic membrane (CAM), mother pock lesions were produced by the isolates from pigeon and turkey in comparison to the isolates from chicken which produced scattered pock lesions. 1997-04 Thesis NonPeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/12326/1/FPV_1997_5_A.pdf Sivasothy, Arumugam (1997) Characterisation And Pathogenicity Studies Of Malaysian Isolates Of Avian Pox Virus. Masters thesis, Universiti Putra Malaysia. Fowl pox - Viruses - Malaysi Poultry - Virus diseases - Malaysia Poxvirus diseases - Malaysia English
spellingShingle Fowl pox - Viruses - Malaysi
Poultry - Virus diseases - Malaysia
Poxvirus diseases - Malaysia
Sivasothy, Arumugam
Characterisation And Pathogenicity Studies Of Malaysian Isolates Of Avian Pox Virus
title Characterisation And Pathogenicity Studies Of Malaysian Isolates Of Avian Pox Virus
title_full Characterisation And Pathogenicity Studies Of Malaysian Isolates Of Avian Pox Virus
title_fullStr Characterisation And Pathogenicity Studies Of Malaysian Isolates Of Avian Pox Virus
title_full_unstemmed Characterisation And Pathogenicity Studies Of Malaysian Isolates Of Avian Pox Virus
title_short Characterisation And Pathogenicity Studies Of Malaysian Isolates Of Avian Pox Virus
title_sort characterisation and pathogenicity studies of malaysian isolates of avian pox virus
topic Fowl pox - Viruses - Malaysi
Poultry - Virus diseases - Malaysia
Poxvirus diseases - Malaysia
url http://psasir.upm.edu.my/id/eprint/12326/
http://psasir.upm.edu.my/id/eprint/12326/1/FPV_1997_5_A.pdf