Genomic landscape of childhood acute lymphoblastic leukemia in Malaysia: insights from array-CGH

QR Code

Genomic landscape of childhood acute lymphoblastic leukemia in Malaysia: insights from array-CGH

Background: Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, comprising approximately 25% of pediatric malignancies. Notably, chromosomal aberrations and genetic alterations play a central role in the pathogenesis of ALL, serving as critical diagnostic and prognostic markers....

Full description

Bibliographic Details
Main Authors:	Ismail, Azli, Ahid, Fadly, Moi, Wong Nyuk, Kamaluddin, Nor Rizan, Esa, Ezalia, Yusoff, Yuslina Mat, Seman, Zahidah Abu, Mohammed, Muhammad Asyraff, George, Elizabeth, Isa, Asmida, Zakaria, Zubaidah
Format:	Article
Language:	English
Published:	BioMed Central 2025
Online Access:	http://psasir.upm.edu.my/id/eprint/120510/ http://psasir.upm.edu.my/id/eprint/120510/1/120510.pdf

Similar Items

Home paint exposures and risk of childhood acute lymphoblastic leukemia: findings from the Childhood Leukemia International Consortium
by: Bailey, H., et al.
Published: (2015)

Exposure to diagnostic radiological procedures and the risk of childhood acute lymphoblastic leukemia
by: Bailey, H., et al.
Published: (2010)

Exposure to professional pest control treatments and the risk of childhood acute lymphoblastic leukemia
by: Bailey, H., et al.
Published: (2011)

Exposure to house painting and the use of floor treatments and the risk of childhood acute lymphoblastic leukemia
by: Bailey, H., et al.
Published: (2011)

Increased regulatory T cells in acute lymphoblastic leukemia patients
by: Idris, Siti Zuleha, et al.
Published: (2015)

Cri-du-chat syndrome: application of array CGH in diagnostic evaluation
by: Zarina AL,, et al.
Published: (2010)

Preclinical efficacy of gemcitabine in MLL-rearranged infant acute lymphoblastic leukemia
by: Wander, P., et al.
Published: (2020)

Home pesticide exposures and risk of childhood leukemia: Findings from the childhood leukemia international consortium
by: Bailey, H., et al.
Published: (2015)

Antileukemogenesis of nypa fruticans on acute lymphoblastic leukemia – a preliminary study in vitro
by: Mamat, Suhana, et al.
Published: (2015)

Parental Occupational Pesticide Exposure and the Risk of Childhood Leukemia in the Offspring: Findings From the Childhood Leukemia International Consortium
by: Bailey, H., et al.
Published: (2014)

Parental Occupational Paint Exposure and Risk of Childhood Leukemia in the Offspring: Findings From the Childhood Leukemia International Consortium
by: Bailey, H., et al.
Published: (2014)

Development of comparative genomic hybridization(CGH) technique for the study of nasopharyngeal carcinoma(NPC)
by: Alwi, Zilfalil, et al.
Published: (2009)

The bone marrow microenvironment of pre-B acute lymphoblastic leukemia at single-cell resolution
by: Anderson, D., et al.
Published: (2020)

Preclinical Evaluation of Carfilzomib for Infant KMT2A-Rearranged Acute Lymphoblastic Leukemia.
by: Cheung, Laurence, et al.
Published: (2021)

Anticancer potential of Damnacanthal and Nordamnacanthal from Morinda elliptica roots on T-lymphoblastic leukemia cells
by: Saiful Yazan, Latifah, et al.
Published: (2021)

Effects of acute lymphoblastic leukemia on ceruloplasmin oxidase, copper and several markers of oxidative damage, in children
by: Mehdi, Wesen Adel, et al.
Published: (2015)

Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia.
by: Roels, Juliette, et al.
Published: (2020)

Maternal folate and other vitamin supplementation during pregnancy and risk of acute lymphoblastic leukemia in the offspring
by: Milne, Elizabeth, et al.
Published: (2010)

ADAMTSL5 and CDH11: putative epigenetic markers for therapeutic resistance in acute lymphoblastic leukemia
by: Abdullah, Maha, et al.
Published: (2017)

TERF2 gene expression in childhood acute lymphoblastic leukaemia / Lelamekala Vengidasan
by: Vengidasan, Lelamekala
Published: (2011)

Risk of childhood acute lymphoblastic leukaemia following parental occupational exposure to pesticides
by: Glass, D., et al.
Published: (2012)

Refuelling of vehicles, the use of wood burners and the risk of acute lymphoblastic leukaemia in childhood
by: Bailey, H., et al.
Published: (2011)

CD26: A prognostic marker of acute lymphoblastic leukemia in children in the post remission induction phase
by: Mende, Atheer Awad, et al.
Published: (2015)

Targeting the bone marrow microenvironment: A novel therapeutic strategy for pre-B acute lymphoblastic leukemia
by: Kotecha, R., et al.
Published: (2019)

Systematic chemical and molecular profiling of MLL-rearranged infant acute lymphoblastic leukemia reveals efficacy of romidepsin
by: Cruickshank, M., et al.
Published: (2017)

RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia.
by: Matthijssens, Filip, et al.
Published: (2021)

Influence of wild-type MLL on glucocorticoid sensitivity and response to DNA-damage in pediatric acute lymphoblastic leukemia
by: Beesley, A., et al.
Published: (2010)

Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma
by: De Smedt, Renate, et al.
Published: (2020)

Amelioration of human acute lymphoblastic leukemia (ALL) cells by ZnO-TiO2-Chitosan-Amygdalin nanocomposites
by: Elderdery, Abozer Y., et al.
Published: (2022)

Molecular mechanism underlying aberrant expression of the connective tissue growth factor in paediatric pre-B cell acute lymphoblastic leukemia
by: Welch, Mathew D.
Published: (2011)

Disseminated fusariosis and endogenous fungal endophthalmitis in acute lymphoblastic leukemia following platelet transfusion possibly due to transfusion-related immunomodulation
by: Tan, Aik Kah, et al.
Published: (2011)

Ultrastructural and morphological effects in T-lymphoblastic leukemia CEM-SS cells following treatment with nordamnacanthal and damnacanthal from roots of Morinda elliptica
by: Latifah, Saiful Yazan, et al.
Published: (2022)

Minimal residual disease status in childhood acute lymphoblastic leukaemias by flow cytometry and their clinical and haematological features
by: Azma RZ,, et al.
Published: (2010)

Parental occupational exposure to exhausts, solvents, glues and paints, and risk of childhood leukemia
by: Reid, A., et al.
Published: (2011)

In Vitro evaluation of T- cell Acute Lymphoblastic Leukemia cell line response to a combination of dual anticancer agent: SRJ23 and Hydroxyurea
by: Khalid, Bahariah, et al.
Published: (2024)

Screening Of Malaysian Patients With Nasopharyngeal Carcinoma (NPC) Using Comparative Genomic Hybridization (CGH) Technique For Identification Of Specific Genetic Alteration
by: Nor, Natasya Naili Muhamad
Published: (2012)

Risk of childhood acute lymphoblastic leukaemia following parental occupational exposure to extremely low frequency electromagnetic fields
by: Reid, A., et al.
Published: (2011)

Novelty of 18F–fluorocholine computed tomography (18-FCHPETCT) in predicting quality of life in malignant breast cancer patients
by: Zakaria, Mohd Hazeman, et al.
Published: (2024)

Romidepsin enhances the efficacy of cytarabine in vivo, revealing histone deacetylase inhibition as a promising therapeutic strategy for KMT2A-rearranged infant acute lymphoblastic leukemia
by: Cheung, Laurence, et al.
Published: (2019)

Zerumbone-loaded nanostructured lipid carrier induces G2/M cell cycle arrest and apoptosis via mitochondrial pathway in a human lymphoblastic leukemia cell line
by: Rahman, Heshu Sulaiman, et al.
Published: (2014)