Sequestration of doxycycline and mefenamic acid from liquid phase using 1,3-diaminopropane modified poly(acrylonitrile-acrylic acid): isotherm, kinetic and mechanism studies

Accumulation of pharmaceutical residues in aquatic environment due to daily consumption by humans and animals for diseases treatment results in alarming long-term effects. This study evaluates the adsorption potential of a polymer-based adsorbent, 1,3-diaminopropane-modified poly(acrylonitrile-acryl...

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Main Authors: Lee, Fatimah, Md Jamil, Siti Nurul Ain, Subri, Nur Nida Syamimi, Adeyi, Abel Adekanmi, Daik, Rusli
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2025
Online Access:http://psasir.upm.edu.my/id/eprint/120300/
http://psasir.upm.edu.my/id/eprint/120300/1/120300.pdf
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author Lee, Fatimah
Md Jamil, Siti Nurul Ain
Subri, Nur Nida Syamimi
Adeyi, Abel Adekanmi
Daik, Rusli
author_facet Lee, Fatimah
Md Jamil, Siti Nurul Ain
Subri, Nur Nida Syamimi
Adeyi, Abel Adekanmi
Daik, Rusli
author_sort Lee, Fatimah
building UPM Institutional Repository
collection Online Access
description Accumulation of pharmaceutical residues in aquatic environment due to daily consumption by humans and animals for diseases treatment results in alarming long-term effects. This study evaluates the adsorption potential of a polymer-based adsorbent, 1,3-diaminopropane-modified poly(acrylonitrile-acrylic acid) (DAP-poly(ACN/AA)), for the uptake of doxycycline (DOX) and mefenamic acid (MEFA) from aqueous solution. The chemical modification of poly(ACN/ AA) copolymer with DAP was successful as suggested by the FTIR spectra and microanalysis results. The SEM analysis showed that the modified copolymer has larger particle size, which was 156 nm as compared to that of poly(ACN/AA) copolymer (133 nm). The influence of adsorbent dosage, contact time, pH and initial concentration on the adsorption of DOX and MEFA compounds were investigated. The kinetic studies of DOX and MEFA was fitted well to pseudo-second-order model with chemisorption being the rate-controlling step. The equilibrium isotherm has its fitness in the following order: Langmuir model > Freundlich model > Temkin model. The maximum adsorption capacities for DOX and MEFA were 210.4 mg/g and 313.7 mg/g, respectively. The excellent high sorption capacity suggest that DAP-modified poly(ACN/ AA) copolymer is a potential adsorbent for the treatment of DOX and MEFA bearing effluent in adsorption system.
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spelling upm-1203002025-09-30T02:04:37Z http://psasir.upm.edu.my/id/eprint/120300/ Sequestration of doxycycline and mefenamic acid from liquid phase using 1,3-diaminopropane modified poly(acrylonitrile-acrylic acid): isotherm, kinetic and mechanism studies Lee, Fatimah Md Jamil, Siti Nurul Ain Subri, Nur Nida Syamimi Adeyi, Abel Adekanmi Daik, Rusli Accumulation of pharmaceutical residues in aquatic environment due to daily consumption by humans and animals for diseases treatment results in alarming long-term effects. This study evaluates the adsorption potential of a polymer-based adsorbent, 1,3-diaminopropane-modified poly(acrylonitrile-acrylic acid) (DAP-poly(ACN/AA)), for the uptake of doxycycline (DOX) and mefenamic acid (MEFA) from aqueous solution. The chemical modification of poly(ACN/ AA) copolymer with DAP was successful as suggested by the FTIR spectra and microanalysis results. The SEM analysis showed that the modified copolymer has larger particle size, which was 156 nm as compared to that of poly(ACN/AA) copolymer (133 nm). The influence of adsorbent dosage, contact time, pH and initial concentration on the adsorption of DOX and MEFA compounds were investigated. The kinetic studies of DOX and MEFA was fitted well to pseudo-second-order model with chemisorption being the rate-controlling step. The equilibrium isotherm has its fitness in the following order: Langmuir model > Freundlich model > Temkin model. The maximum adsorption capacities for DOX and MEFA were 210.4 mg/g and 313.7 mg/g, respectively. The excellent high sorption capacity suggest that DAP-modified poly(ACN/ AA) copolymer is a potential adsorbent for the treatment of DOX and MEFA bearing effluent in adsorption system. Penerbit Universiti Kebangsaan Malaysia 2025 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/120300/1/120300.pdf Lee, Fatimah and Md Jamil, Siti Nurul Ain and Subri, Nur Nida Syamimi and Adeyi, Abel Adekanmi and Daik, Rusli (2025) Sequestration of doxycycline and mefenamic acid from liquid phase using 1,3-diaminopropane modified poly(acrylonitrile-acrylic acid): isotherm, kinetic and mechanism studies. Sains Malaysiana, 54 (1). art. no. undefined. pp. 3687-3704. ISSN 0126-6039 https://www.ukm.my/jsm/pdf_files/SM-PDF-54-1-2025/18.pdf 10.17576/jsm-2025-5401-18
spellingShingle Lee, Fatimah
Md Jamil, Siti Nurul Ain
Subri, Nur Nida Syamimi
Adeyi, Abel Adekanmi
Daik, Rusli
Sequestration of doxycycline and mefenamic acid from liquid phase using 1,3-diaminopropane modified poly(acrylonitrile-acrylic acid): isotherm, kinetic and mechanism studies
title Sequestration of doxycycline and mefenamic acid from liquid phase using 1,3-diaminopropane modified poly(acrylonitrile-acrylic acid): isotherm, kinetic and mechanism studies
title_full Sequestration of doxycycline and mefenamic acid from liquid phase using 1,3-diaminopropane modified poly(acrylonitrile-acrylic acid): isotherm, kinetic and mechanism studies
title_fullStr Sequestration of doxycycline and mefenamic acid from liquid phase using 1,3-diaminopropane modified poly(acrylonitrile-acrylic acid): isotherm, kinetic and mechanism studies
title_full_unstemmed Sequestration of doxycycline and mefenamic acid from liquid phase using 1,3-diaminopropane modified poly(acrylonitrile-acrylic acid): isotherm, kinetic and mechanism studies
title_short Sequestration of doxycycline and mefenamic acid from liquid phase using 1,3-diaminopropane modified poly(acrylonitrile-acrylic acid): isotherm, kinetic and mechanism studies
title_sort sequestration of doxycycline and mefenamic acid from liquid phase using 1,3-diaminopropane modified poly(acrylonitrile-acrylic acid): isotherm, kinetic and mechanism studies
url http://psasir.upm.edu.my/id/eprint/120300/
http://psasir.upm.edu.my/id/eprint/120300/
http://psasir.upm.edu.my/id/eprint/120300/
http://psasir.upm.edu.my/id/eprint/120300/1/120300.pdf