Prenatal ruxolitinib treatment improved muscle strength but showed no impact on the neurobehavioral and electrophysiological traits in adult mice

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Prenatal ruxolitinib treatment improved muscle strength but showed no impact on the neurobehavioral and electrophysiological traits in adult mice

The JAK/STAT signalling pathway is essential for cell communication and gene expression, particularly in brain development. Its dysregulation relates to neurological conditions such as Down syndrome and Noonan syndrome, impacting the shift from neuron to astrocyte production. Ruxolitinib, an FDA app...

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Bibliographic Details
Main Authors:	Azimzadeh, Mansour, Lim, Shi En, Mazhar, Nurul Syahirah, Ling, King Hwa, Cheah, Pike See
Format:	Article
Language:	English
Published:	Pleiades Publishing 2024
Online Access:	http://psasir.upm.edu.my/id/eprint/119356/ http://psasir.upm.edu.my/id/eprint/119356/1/119356.pdf

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