Herbal medicine: a promising approach for the treatment of Alzheimer's disease
Alzheimer's disease is a progressive neurodegenerative disease manifesting in cognitive decline, impairment of memory, and behavioural deterioration. Alzheimer’s is a relatively common type of dementia. The pathological basis for the progression of Alzheimer's disease is beta-amyloid prote...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Mahadev Publications
2024
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| Online Access: | http://psasir.upm.edu.my/id/eprint/119198/ http://psasir.upm.edu.my/id/eprint/119198/1/119198.pdf |
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| author | Vishnumukkala, Thirupathirao Gopalakrishna, Prarthana Kalerammana Jagadeesan, Saravanan Musa Chiroma, Samaila Mohd Nor, Nurul Huda Baharuldin, Mohamad Taufik Hidayat Thomas, Warren Mohd Moklas, Mohamad Aris |
| author_facet | Vishnumukkala, Thirupathirao Gopalakrishna, Prarthana Kalerammana Jagadeesan, Saravanan Musa Chiroma, Samaila Mohd Nor, Nurul Huda Baharuldin, Mohamad Taufik Hidayat Thomas, Warren Mohd Moklas, Mohamad Aris |
| author_sort | Vishnumukkala, Thirupathirao |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Alzheimer's disease is a progressive neurodegenerative disease manifesting in cognitive decline, impairment of memory, and behavioural deterioration. Alzheimer’s is a relatively common type of dementia. The pathological basis for the progression of Alzheimer's disease is beta-amyloid protein accumulation, phosphorylation of tau protein, abnormal glial cell function, inflammation, neurotransmitter imbalance, along with oxidative stress in brain tissue. Current available therapies are targeted at amelioration of symptoms alone and focus on a limited spectrum of pathophysiological processes. It is evident that it is essential to develop a multi-target therapeutic option in managing Alzheimer's disease, in view of the broad range of factors in disease progression and sever consequences for sufferers. Herbal medicines are seen as a potential resource in the treatment of Alzheimer's disease, in view of their historical use in traditional medicine as neuroprotectants. Herbal medicines have been evaluated in animal studies designed to determine their capacity to prevent neurodegenerative disease and ameliorate memory defects. This review elaborates on the studies conducted on several medicinal plants that have been investigated for their potential in the prevention and treatment of memory defects in animal models. |
| first_indexed | 2025-11-15T14:43:51Z |
| format | Article |
| id | upm-119198 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:43:51Z |
| publishDate | 2024 |
| publisher | Mahadev Publications |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1191982025-08-11T03:31:41Z http://psasir.upm.edu.my/id/eprint/119198/ Herbal medicine: a promising approach for the treatment of Alzheimer's disease Vishnumukkala, Thirupathirao Gopalakrishna, Prarthana Kalerammana Jagadeesan, Saravanan Musa Chiroma, Samaila Mohd Nor, Nurul Huda Baharuldin, Mohamad Taufik Hidayat Thomas, Warren Mohd Moklas, Mohamad Aris Alzheimer's disease is a progressive neurodegenerative disease manifesting in cognitive decline, impairment of memory, and behavioural deterioration. Alzheimer’s is a relatively common type of dementia. The pathological basis for the progression of Alzheimer's disease is beta-amyloid protein accumulation, phosphorylation of tau protein, abnormal glial cell function, inflammation, neurotransmitter imbalance, along with oxidative stress in brain tissue. Current available therapies are targeted at amelioration of symptoms alone and focus on a limited spectrum of pathophysiological processes. It is evident that it is essential to develop a multi-target therapeutic option in managing Alzheimer's disease, in view of the broad range of factors in disease progression and sever consequences for sufferers. Herbal medicines are seen as a potential resource in the treatment of Alzheimer's disease, in view of their historical use in traditional medicine as neuroprotectants. Herbal medicines have been evaluated in animal studies designed to determine their capacity to prevent neurodegenerative disease and ameliorate memory defects. This review elaborates on the studies conducted on several medicinal plants that have been investigated for their potential in the prevention and treatment of memory defects in animal models. Mahadev Publications 2024-02-04 Article PeerReviewed text en cc_by_nc_sa_4 http://psasir.upm.edu.my/id/eprint/119198/1/119198.pdf Vishnumukkala, Thirupathirao and Gopalakrishna, Prarthana Kalerammana and Jagadeesan, Saravanan and Musa Chiroma, Samaila and Mohd Nor, Nurul Huda and Baharuldin, Mohamad Taufik Hidayat and Thomas, Warren and Mohd Moklas, Mohamad Aris (2024) Herbal medicine: a promising approach for the treatment of Alzheimer's disease. International Journal of Ayurveda and Pharma Research, 12 (1). pp. 142-150. ISSN 2322 -0902; eISSN: 2322-0910 https://ijapr.in/index.php/ijapr/article/view/3103 10.47070/ijapr.v12i1.3103 |
| spellingShingle | Vishnumukkala, Thirupathirao Gopalakrishna, Prarthana Kalerammana Jagadeesan, Saravanan Musa Chiroma, Samaila Mohd Nor, Nurul Huda Baharuldin, Mohamad Taufik Hidayat Thomas, Warren Mohd Moklas, Mohamad Aris Herbal medicine: a promising approach for the treatment of Alzheimer's disease |
| title | Herbal medicine: a promising approach for the treatment of Alzheimer's disease |
| title_full | Herbal medicine: a promising approach for the treatment of Alzheimer's disease |
| title_fullStr | Herbal medicine: a promising approach for the treatment of Alzheimer's disease |
| title_full_unstemmed | Herbal medicine: a promising approach for the treatment of Alzheimer's disease |
| title_short | Herbal medicine: a promising approach for the treatment of Alzheimer's disease |
| title_sort | herbal medicine: a promising approach for the treatment of alzheimer's disease |
| url | http://psasir.upm.edu.my/id/eprint/119198/ http://psasir.upm.edu.my/id/eprint/119198/ http://psasir.upm.edu.my/id/eprint/119198/ http://psasir.upm.edu.my/id/eprint/119198/1/119198.pdf |