Pneumonia – the silent renal killer

A 48-year-old woman presented with intermittent fever, dyspnea, hand and limb swelling, and purplish plantar spots. Initially diagnosed with pneumonia, she was later found to have mixed connective tissue disease and interstitial lung disease. She required oxygen support, had stable vitals, and exhib...

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Main Authors: Aravan, Logaruban, Lim, Christopher Thiam Seong, Abd Ghani, Fauzah, Mohamad, Haidi
Format: Article
Language:English
Published: Malaysian Society Of Nephrology 2024
Online Access:http://psasir.upm.edu.my/id/eprint/119073/
http://psasir.upm.edu.my/id/eprint/119073/1/119073.pdf
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author Aravan, Logaruban
Lim, Christopher Thiam Seong
Abd Ghani, Fauzah
Mohamad, Haidi
author_facet Aravan, Logaruban
Lim, Christopher Thiam Seong
Abd Ghani, Fauzah
Mohamad, Haidi
author_sort Aravan, Logaruban
building UPM Institutional Repository
collection Online Access
description A 48-year-old woman presented with intermittent fever, dyspnea, hand and limb swelling, and purplish plantar spots. Initially diagnosed with pneumonia, she was later found to have mixed connective tissue disease and interstitial lung disease. She required oxygen support, had stable vitals, and exhibited lung crepitations and bilateral pedal edema. Patient had elevated white blood cells, platelets, CRP, creatinine, positive c- Antineutrophil Cytoplasmic Antibody (Anca) and significant proteinuria and hematuria. Initial impression was mixed connective tissue disease with pre renal Acute Kidney Injury (AKI) with differentials of sepsis induced AKI , Anca related Glomerulonephritis (GN) or Infection related GN. Renal biopsy shows a diffuse sclerosing pattern changes with granulomatous nephritis. Negative Immunofluorescence (IF) study concluded sclerosing and granulomatous form of ANCA related pauci-immune glomerulonephritis.
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publisher Malaysian Society Of Nephrology
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spelling upm-1190732025-08-06T02:24:58Z http://psasir.upm.edu.my/id/eprint/119073/ Pneumonia – the silent renal killer Aravan, Logaruban Lim, Christopher Thiam Seong Abd Ghani, Fauzah Mohamad, Haidi A 48-year-old woman presented with intermittent fever, dyspnea, hand and limb swelling, and purplish plantar spots. Initially diagnosed with pneumonia, she was later found to have mixed connective tissue disease and interstitial lung disease. She required oxygen support, had stable vitals, and exhibited lung crepitations and bilateral pedal edema. Patient had elevated white blood cells, platelets, CRP, creatinine, positive c- Antineutrophil Cytoplasmic Antibody (Anca) and significant proteinuria and hematuria. Initial impression was mixed connective tissue disease with pre renal Acute Kidney Injury (AKI) with differentials of sepsis induced AKI , Anca related Glomerulonephritis (GN) or Infection related GN. Renal biopsy shows a diffuse sclerosing pattern changes with granulomatous nephritis. Negative Immunofluorescence (IF) study concluded sclerosing and granulomatous form of ANCA related pauci-immune glomerulonephritis. Malaysian Society Of Nephrology 2024-09-01 Article PeerReviewed text en cc_by_4 http://psasir.upm.edu.my/id/eprint/119073/1/119073.pdf Aravan, Logaruban and Lim, Christopher Thiam Seong and Abd Ghani, Fauzah and Mohamad, Haidi (2024) Pneumonia – the silent renal killer. Journal of Clinical and Translational Nephrology, 3 (4). pp. 1-2. ISSN 2710-5903 https://jctn.msn.org.my/index.php/ejournal/article/view/79
spellingShingle Aravan, Logaruban
Lim, Christopher Thiam Seong
Abd Ghani, Fauzah
Mohamad, Haidi
Pneumonia – the silent renal killer
title Pneumonia – the silent renal killer
title_full Pneumonia – the silent renal killer
title_fullStr Pneumonia – the silent renal killer
title_full_unstemmed Pneumonia – the silent renal killer
title_short Pneumonia – the silent renal killer
title_sort pneumonia – the silent renal killer
url http://psasir.upm.edu.my/id/eprint/119073/
http://psasir.upm.edu.my/id/eprint/119073/
http://psasir.upm.edu.my/id/eprint/119073/1/119073.pdf