Nephrotic syndrome in young adolescent
CASE PRESENTATION: A 13-year-old female presented with a one-week history of bilateral lower limb swelling associated with cough and sore throat. There was no fever, breathlessness, hematuria, or frothy urine. She denied connective tissue disease-related symptoms. There was also no family histo...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Malaysian Society Of Nephrology
2024
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| Online Access: | http://psasir.upm.edu.my/id/eprint/119072/ http://psasir.upm.edu.my/id/eprint/119072/1/119072.pdf |
| _version_ | 1848867865358237696 |
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| author | Tee, Tat Khoo Lim, Christopher Thiam Seong Mohamad, Haidi Mohamad Mokhtar, Elmina Bak, Leong Goh |
| author_facet | Tee, Tat Khoo Lim, Christopher Thiam Seong Mohamad, Haidi Mohamad Mokhtar, Elmina Bak, Leong Goh |
| author_sort | Tee, Tat Khoo |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | CASE PRESENTATION: A 13-year-old female presented with a one-week history
of bilateral lower limb swelling associated with cough
and sore throat. There was no fever, breathlessness,
hematuria, or frothy urine. She denied connective tissue
disease-related symptoms. There was also no family
history of autoimmune disease or chronic kidney disease.
On examination, her blood pressure was 135/91 mmHg
with conjunctival pallor and lower limb pitting oedema.
Her initial investigation showed haemoglobin of 9g/dL,
LDH 390U/L, positive Coombs test with IgG 2+ and
C3D 3+, and peripheral blood film showed spherocytes
with no schistocytes or agglutination. Her creatinine was
40 μmol/L, urine protein 4+ blood 1+, 24-hour urinary
protein of 7.4g/day and low albumin of 20g/dL. Her viral
screening was non-reactive, and an immunology workup
revealed negative ANA with normal C3 and C4 levels as
well as negative ASOT. |
| first_indexed | 2025-11-15T14:43:17Z |
| format | Article |
| id | upm-119072 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:43:17Z |
| publishDate | 2024 |
| publisher | Malaysian Society Of Nephrology |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1190722025-08-05T09:38:59Z http://psasir.upm.edu.my/id/eprint/119072/ Nephrotic syndrome in young adolescent Tee, Tat Khoo Lim, Christopher Thiam Seong Mohamad, Haidi Mohamad Mokhtar, Elmina Bak, Leong Goh CASE PRESENTATION: A 13-year-old female presented with a one-week history of bilateral lower limb swelling associated with cough and sore throat. There was no fever, breathlessness, hematuria, or frothy urine. She denied connective tissue disease-related symptoms. There was also no family history of autoimmune disease or chronic kidney disease. On examination, her blood pressure was 135/91 mmHg with conjunctival pallor and lower limb pitting oedema. Her initial investigation showed haemoglobin of 9g/dL, LDH 390U/L, positive Coombs test with IgG 2+ and C3D 3+, and peripheral blood film showed spherocytes with no schistocytes or agglutination. Her creatinine was 40 μmol/L, urine protein 4+ blood 1+, 24-hour urinary protein of 7.4g/day and low albumin of 20g/dL. Her viral screening was non-reactive, and an immunology workup revealed negative ANA with normal C3 and C4 levels as well as negative ASOT. Malaysian Society Of Nephrology 2024-09-01 Article PeerReviewed text en cc_by_4 http://psasir.upm.edu.my/id/eprint/119072/1/119072.pdf Tee, Tat Khoo and Lim, Christopher Thiam Seong and Mohamad, Haidi and Mohamad Mokhtar, Elmina and Bak, Leong Goh (2024) Nephrotic syndrome in young adolescent. Journal of Clinical and Translational Nephrology, 3 (3). pp. 1-2. ISSN 2710-5903 https://www.jctn.msn.org.my/index.php/ejournal/article/view/82 |
| spellingShingle | Tee, Tat Khoo Lim, Christopher Thiam Seong Mohamad, Haidi Mohamad Mokhtar, Elmina Bak, Leong Goh Nephrotic syndrome in young adolescent |
| title | Nephrotic syndrome in young adolescent |
| title_full | Nephrotic syndrome in young adolescent |
| title_fullStr | Nephrotic syndrome in young adolescent |
| title_full_unstemmed | Nephrotic syndrome in young adolescent |
| title_short | Nephrotic syndrome in young adolescent |
| title_sort | nephrotic syndrome in young adolescent |
| url | http://psasir.upm.edu.my/id/eprint/119072/ http://psasir.upm.edu.my/id/eprint/119072/ http://psasir.upm.edu.my/id/eprint/119072/1/119072.pdf |