Rare renal manifestation of plasma cell disorder

CASE PRESENTATION: A 56 year old lady presented with 2 weeks history of nausea, vomiting, and unintentional weight loss, with reduced eff 01t tolerance. She has underlying type 2 diabetes mellitus, and hype1tension. On examination, blood pressure was 140 / 80mmhg, pallor conjunctivae, and other...

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Main Authors: Shahar, Shamira, Lim, Christopher Thiam Seong, Mohamad, Haidi, Abd Ghani, Fauzah, Bak, Leong Goh
Format: Article
Language:English
Published: Malaysian Society of Nephrology 2024
Online Access:http://psasir.upm.edu.my/id/eprint/119071/
http://psasir.upm.edu.my/id/eprint/119071/1/119071.pdf
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author Shahar, Shamira
Lim, Christopher Thiam Seong
Mohamad, Haidi
Abd Ghani, Fauzah
Bak, Leong Goh
author_facet Shahar, Shamira
Lim, Christopher Thiam Seong
Mohamad, Haidi
Abd Ghani, Fauzah
Bak, Leong Goh
author_sort Shahar, Shamira
building UPM Institutional Repository
collection Online Access
description CASE PRESENTATION: A 56 year old lady presented with 2 weeks history of nausea, vomiting, and unintentional weight loss, with reduced eff 01t tolerance. She has underlying type 2 diabetes mellitus, and hype1tension. On examination, blood pressure was 140 / 80mmhg, pallor conjunctivae, and other physical examination was normal. Her investigations showed creatinine of 1214 umol/L, urea 24.3 mmol/L, eGFR of 2 ml/min/1.73m2, albumin 35 g/L, total protein 71g/L, globulin 34g/L, albumin /globulin ratio 1.08, haemoglobin 6.8 g/dl, platelet 312x 103/uL, total white cell 7.97 x 10 9/L, calcium 2.44 mmol/L, phosphate 2 mmol/L, and e1ythrocyte sedimentation rate (ESR) 100 mm/hr. Urine microscopy shows 1 + protein, no REC presence and urine protein creatinine index of 12.9g/day. Immunology screening revealed nonnal ANA, C3, C4, and ANCA. Kidney ultrasound shows a left kidney size of 10.3cm, and right kidney of 11.7cm with preserved cmticomedullary differentiation bilaterally. She was initially diagnosed with ESKD, and long-tenn kidney replacement therapy was planned for her.
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spelling upm-1190712025-08-05T09:30:31Z http://psasir.upm.edu.my/id/eprint/119071/ Rare renal manifestation of plasma cell disorder Shahar, Shamira Lim, Christopher Thiam Seong Mohamad, Haidi Abd Ghani, Fauzah Bak, Leong Goh CASE PRESENTATION: A 56 year old lady presented with 2 weeks history of nausea, vomiting, and unintentional weight loss, with reduced eff 01t tolerance. She has underlying type 2 diabetes mellitus, and hype1tension. On examination, blood pressure was 140 / 80mmhg, pallor conjunctivae, and other physical examination was normal. Her investigations showed creatinine of 1214 umol/L, urea 24.3 mmol/L, eGFR of 2 ml/min/1.73m2, albumin 35 g/L, total protein 71g/L, globulin 34g/L, albumin /globulin ratio 1.08, haemoglobin 6.8 g/dl, platelet 312x 103/uL, total white cell 7.97 x 10 9/L, calcium 2.44 mmol/L, phosphate 2 mmol/L, and e1ythrocyte sedimentation rate (ESR) 100 mm/hr. Urine microscopy shows 1 + protein, no REC presence and urine protein creatinine index of 12.9g/day. Immunology screening revealed nonnal ANA, C3, C4, and ANCA. Kidney ultrasound shows a left kidney size of 10.3cm, and right kidney of 11.7cm with preserved cmticomedullary differentiation bilaterally. She was initially diagnosed with ESKD, and long-tenn kidney replacement therapy was planned for her. Malaysian Society of Nephrology 2024-09-01 Article PeerReviewed text en cc_by_4 http://psasir.upm.edu.my/id/eprint/119071/1/119071.pdf Shahar, Shamira and Lim, Christopher Thiam Seong and Mohamad, Haidi and Abd Ghani, Fauzah and Bak, Leong Goh (2024) Rare renal manifestation of plasma cell disorder. Journal of Clinical and Translational Nephrology, 3 (2). pp. 1-2. ISSN 2710-5903 https://www.jctn.msn.org.my/index.php/ejournal/article/view/81
spellingShingle Shahar, Shamira
Lim, Christopher Thiam Seong
Mohamad, Haidi
Abd Ghani, Fauzah
Bak, Leong Goh
Rare renal manifestation of plasma cell disorder
title Rare renal manifestation of plasma cell disorder
title_full Rare renal manifestation of plasma cell disorder
title_fullStr Rare renal manifestation of plasma cell disorder
title_full_unstemmed Rare renal manifestation of plasma cell disorder
title_short Rare renal manifestation of plasma cell disorder
title_sort rare renal manifestation of plasma cell disorder
url http://psasir.upm.edu.my/id/eprint/119071/
http://psasir.upm.edu.my/id/eprint/119071/
http://psasir.upm.edu.my/id/eprint/119071/1/119071.pdf