First serological evidence of Coxiella burnetii and Mycobacterium avium subspecies paratuberculosis (MAP) among deer in an institutional farm in Malaysia
Q fever is a zoonotic disease caused by Coxiella burnetii, which is associated with reproductive disorders such as abortion and reproductive problems in ruminants, while paratuberculosis is an underdiagnosed disease caused by Mycobacterium avium paratuberculosis (MAP) which causes chronic wasting, l...
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| Format: | Article |
| Language: | English |
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Faculty of Veterinary Science, Chulalongkorn University
2024
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| Online Access: | http://psasir.upm.edu.my/id/eprint/118930/ http://psasir.upm.edu.my/id/eprint/118930/1/118930.pdf |
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| author | Abdullah, Faez Firdaus Jesse Lim, Eric Teik Chung Mohd Lila, Mohd Azmi Thlama, Bura Paul Sundar, Shivnraj Yosryhan, Nur Hanis Nadhirah Ahmed Jimale, Yonis Norsidin, Mohd Jefri Azhar, Nur Amira |
| author_facet | Abdullah, Faez Firdaus Jesse Lim, Eric Teik Chung Mohd Lila, Mohd Azmi Thlama, Bura Paul Sundar, Shivnraj Yosryhan, Nur Hanis Nadhirah Ahmed Jimale, Yonis Norsidin, Mohd Jefri Azhar, Nur Amira |
| author_sort | Abdullah, Faez Firdaus Jesse |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Q fever is a zoonotic disease caused by Coxiella burnetii, which is associated with reproductive disorders such as abortion and reproductive problems in ruminants, while paratuberculosis is an underdiagnosed disease caused by Mycobacterium avium paratuberculosis (MAP) which causes chronic wasting, low fertility, and mortality in ruminants. Although both C. burnetii and MAP infections have been reported in domestic ruminants worldwide, there is no data on their seroprevalence status among deer in Selangor, Malaysia. This study investigated the seroprevalence status of C. burnetii and MAP among deer in Malaysia. Ninety-two blood sera collected from an institutional deer farm were screened using commercial Multi-species ID Screen indirect ELISA tests to detect specific anti-C. burnetii (FQS-MS/1117) and anti-MAP (PARAS Ver 0516) antibodies. The ELISA results showed a 14.1% (95% CI = 8.5-22.7) apparent and 14.8% (95% CI = 8.4-24.4) true prevalence for C. burnetii and a 2.2% (95% CI= 0.6-7.6) apparent and 1.3% (95% CI= -0.45-7.40) true prevalence for MAP among deer. There were statistically significant associations between seropositivity to C. burnetii and the age groups (χ2= 7.325, P = 0.011) or herds of deer (χ2= 9.732, P = 0.001). To the best of our knowledge, this study provides the first preliminary serological evidence of C. burnetii and MAP in Cervus timorensis, suggesting potential threats to animal and public health in Malaysia. |
| first_indexed | 2025-11-15T14:42:40Z |
| format | Article |
| id | upm-118930 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:42:40Z |
| publishDate | 2024 |
| publisher | Faculty of Veterinary Science, Chulalongkorn University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1189302025-08-06T02:09:49Z http://psasir.upm.edu.my/id/eprint/118930/ First serological evidence of Coxiella burnetii and Mycobacterium avium subspecies paratuberculosis (MAP) among deer in an institutional farm in Malaysia Abdullah, Faez Firdaus Jesse Lim, Eric Teik Chung Mohd Lila, Mohd Azmi Thlama, Bura Paul Sundar, Shivnraj Yosryhan, Nur Hanis Nadhirah Ahmed Jimale, Yonis Norsidin, Mohd Jefri Azhar, Nur Amira Q fever is a zoonotic disease caused by Coxiella burnetii, which is associated with reproductive disorders such as abortion and reproductive problems in ruminants, while paratuberculosis is an underdiagnosed disease caused by Mycobacterium avium paratuberculosis (MAP) which causes chronic wasting, low fertility, and mortality in ruminants. Although both C. burnetii and MAP infections have been reported in domestic ruminants worldwide, there is no data on their seroprevalence status among deer in Selangor, Malaysia. This study investigated the seroprevalence status of C. burnetii and MAP among deer in Malaysia. Ninety-two blood sera collected from an institutional deer farm were screened using commercial Multi-species ID Screen indirect ELISA tests to detect specific anti-C. burnetii (FQS-MS/1117) and anti-MAP (PARAS Ver 0516) antibodies. The ELISA results showed a 14.1% (95% CI = 8.5-22.7) apparent and 14.8% (95% CI = 8.4-24.4) true prevalence for C. burnetii and a 2.2% (95% CI= 0.6-7.6) apparent and 1.3% (95% CI= -0.45-7.40) true prevalence for MAP among deer. There were statistically significant associations between seropositivity to C. burnetii and the age groups (χ2= 7.325, P = 0.011) or herds of deer (χ2= 9.732, P = 0.001). To the best of our knowledge, this study provides the first preliminary serological evidence of C. burnetii and MAP in Cervus timorensis, suggesting potential threats to animal and public health in Malaysia. Faculty of Veterinary Science, Chulalongkorn University 2024 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/118930/1/118930.pdf Abdullah, Faez Firdaus Jesse and Lim, Eric Teik Chung and Mohd Lila, Mohd Azmi and Thlama, Bura Paul and Sundar, Shivnraj and Yosryhan, Nur Hanis Nadhirah and Ahmed Jimale, Yonis and Norsidin, Mohd Jefri and Azhar, Nur Amira (2024) First serological evidence of Coxiella burnetii and Mycobacterium avium subspecies paratuberculosis (MAP) among deer in an institutional farm in Malaysia. Thai Journal of Veterinary Medicine, 54 (1). art. no. 10. pp. 77-82. ISSN 0125-6491; eISSN: 0125-6491 https://digital.car.chula.ac.th/tjvm/vol54/iss1/10/ |
| spellingShingle | Abdullah, Faez Firdaus Jesse Lim, Eric Teik Chung Mohd Lila, Mohd Azmi Thlama, Bura Paul Sundar, Shivnraj Yosryhan, Nur Hanis Nadhirah Ahmed Jimale, Yonis Norsidin, Mohd Jefri Azhar, Nur Amira First serological evidence of Coxiella burnetii and Mycobacterium avium subspecies paratuberculosis (MAP) among deer in an institutional farm in Malaysia |
| title | First serological evidence of Coxiella burnetii and Mycobacterium avium subspecies paratuberculosis (MAP) among deer in an institutional farm in Malaysia |
| title_full | First serological evidence of Coxiella burnetii and Mycobacterium avium subspecies paratuberculosis (MAP) among deer in an institutional farm in Malaysia |
| title_fullStr | First serological evidence of Coxiella burnetii and Mycobacterium avium subspecies paratuberculosis (MAP) among deer in an institutional farm in Malaysia |
| title_full_unstemmed | First serological evidence of Coxiella burnetii and Mycobacterium avium subspecies paratuberculosis (MAP) among deer in an institutional farm in Malaysia |
| title_short | First serological evidence of Coxiella burnetii and Mycobacterium avium subspecies paratuberculosis (MAP) among deer in an institutional farm in Malaysia |
| title_sort | first serological evidence of coxiella burnetii and mycobacterium avium subspecies paratuberculosis (map) among deer in an institutional farm in malaysia |
| url | http://psasir.upm.edu.my/id/eprint/118930/ http://psasir.upm.edu.my/id/eprint/118930/ http://psasir.upm.edu.my/id/eprint/118930/1/118930.pdf |