Dietary effects of astaxanthin on gonadal development in female broodstock of Macrobrachium rosenbergii
This study examines the effects of dietary astaxanthin on ovarian development and reproductive health in female Macrobrachium rosenbergii, a key aquaculture species. Five isonitrogenous and isolipidic diets with astaxanthin levels of 0, 27, 62, 140, and 310 mg/kg (AS0, AS27, AS62, AS140, AS310) were...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier B.V.
2025
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| Online Access: | http://psasir.upm.edu.my/id/eprint/118739/ http://psasir.upm.edu.my/id/eprint/118739/1/118739.pdf |
| _version_ | 1848867773922410496 |
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| author | Tao, Mingwei Wei, Jie de Cruz, Clement Wang, Junyi Du, Houkuan Zhou, Hangxian Xu, Qiyou |
| author_facet | Tao, Mingwei Wei, Jie de Cruz, Clement Wang, Junyi Du, Houkuan Zhou, Hangxian Xu, Qiyou |
| author_sort | Tao, Mingwei |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | This study examines the effects of dietary astaxanthin on ovarian development and reproductive health in female Macrobrachium rosenbergii, a key aquaculture species. Five isonitrogenous and isolipidic diets with astaxanthin levels of 0, 27, 62, 140, and 310 mg/kg (AS0, AS27, AS62, AS140, AS310) were tested over 56 days. Weight gain and specific growth rates were significantly higher in AS27, AS62, and AS140 compared to AS0 (P < 0.05). Survival rates were significantly higher in AS62, AS140, and AS310 compared to AS0 and AS27 (P < 0.05). The AS62 group exhibited the highest gonadosomatic index and estradiol levels, while vitellogenin levels were elevated in AS62 and AS140 (P < 0.05). Testosterone was significantly higher in AS27 and AS62 compared to AS310 (P < 0.05). Oxidative stress indicators showed lower malondialdehyde levels and higher superoxide dismutase activity in AS62, with total antioxidant capacity peaking in AS140 (P < 0.05). Transcriptome analysis revealed upregulation of genes involved in the pentose phosphate pathway, glutathione metabolism, and ubiquinone/terpenoid-quinone biosynthesis in AS140. Specifically, genes such as g6pd, fbp, gpx, and anpep were significantly upregulated (P < 0.05). Optimal astaxanthin levels (114.30–165.14 mg/kg) enhanced gonadal development, antioxidant capacity, and sex hormone regulation. This study provides insights into the molecular pathways through which astaxanthin supports reproductive health in broodstock M. rosenbergii. |
| first_indexed | 2025-11-15T14:38:52Z |
| format | Article |
| id | upm-118739 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:38:52Z |
| publishDate | 2025 |
| publisher | Elsevier B.V. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1187392025-07-23T02:56:03Z http://psasir.upm.edu.my/id/eprint/118739/ Dietary effects of astaxanthin on gonadal development in female broodstock of Macrobrachium rosenbergii Tao, Mingwei Wei, Jie de Cruz, Clement Wang, Junyi Du, Houkuan Zhou, Hangxian Xu, Qiyou This study examines the effects of dietary astaxanthin on ovarian development and reproductive health in female Macrobrachium rosenbergii, a key aquaculture species. Five isonitrogenous and isolipidic diets with astaxanthin levels of 0, 27, 62, 140, and 310 mg/kg (AS0, AS27, AS62, AS140, AS310) were tested over 56 days. Weight gain and specific growth rates were significantly higher in AS27, AS62, and AS140 compared to AS0 (P < 0.05). Survival rates were significantly higher in AS62, AS140, and AS310 compared to AS0 and AS27 (P < 0.05). The AS62 group exhibited the highest gonadosomatic index and estradiol levels, while vitellogenin levels were elevated in AS62 and AS140 (P < 0.05). Testosterone was significantly higher in AS27 and AS62 compared to AS310 (P < 0.05). Oxidative stress indicators showed lower malondialdehyde levels and higher superoxide dismutase activity in AS62, with total antioxidant capacity peaking in AS140 (P < 0.05). Transcriptome analysis revealed upregulation of genes involved in the pentose phosphate pathway, glutathione metabolism, and ubiquinone/terpenoid-quinone biosynthesis in AS140. Specifically, genes such as g6pd, fbp, gpx, and anpep were significantly upregulated (P < 0.05). Optimal astaxanthin levels (114.30–165.14 mg/kg) enhanced gonadal development, antioxidant capacity, and sex hormone regulation. This study provides insights into the molecular pathways through which astaxanthin supports reproductive health in broodstock M. rosenbergii. Elsevier B.V. 2025 Article PeerReviewed text en cc_by_4 http://psasir.upm.edu.my/id/eprint/118739/1/118739.pdf Tao, Mingwei and Wei, Jie and de Cruz, Clement and Wang, Junyi and Du, Houkuan and Zhou, Hangxian and Xu, Qiyou (2025) Dietary effects of astaxanthin on gonadal development in female broodstock of Macrobrachium rosenbergii. Aquaculture Reports, 42. art. no. 102841. pp. 1-12. ISSN 2352-5134 https://linkinghub.elsevier.com/retrieve/pii/S2352513425002273 10.1016/j.aqrep.2025.102841 |
| spellingShingle | Tao, Mingwei Wei, Jie de Cruz, Clement Wang, Junyi Du, Houkuan Zhou, Hangxian Xu, Qiyou Dietary effects of astaxanthin on gonadal development in female broodstock of Macrobrachium rosenbergii |
| title | Dietary effects of astaxanthin on gonadal development in female broodstock of Macrobrachium rosenbergii |
| title_full | Dietary effects of astaxanthin on gonadal development in female broodstock of Macrobrachium rosenbergii |
| title_fullStr | Dietary effects of astaxanthin on gonadal development in female broodstock of Macrobrachium rosenbergii |
| title_full_unstemmed | Dietary effects of astaxanthin on gonadal development in female broodstock of Macrobrachium rosenbergii |
| title_short | Dietary effects of astaxanthin on gonadal development in female broodstock of Macrobrachium rosenbergii |
| title_sort | dietary effects of astaxanthin on gonadal development in female broodstock of macrobrachium rosenbergii |
| url | http://psasir.upm.edu.my/id/eprint/118739/ http://psasir.upm.edu.my/id/eprint/118739/ http://psasir.upm.edu.my/id/eprint/118739/ http://psasir.upm.edu.my/id/eprint/118739/1/118739.pdf |