Efficacy of Caprini risk assessment model in predicting venous thromboembolism risks among Asian surgical patients
Introduction: Caprini risk assessment model (RAM) has been validated in Caucasians but evidence of its suitability in Asian surgical patients is still unknown. This study aims to determine the efficacy of Caprini model in venous thromboembolism (VTE) risk assessment among Asian surgical patients. Ma...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Malaysian Medical Association
2024
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| Online Access: | http://psasir.upm.edu.my/id/eprint/118677/ http://psasir.upm.edu.my/id/eprint/118677/1/118677.pdf |
| _version_ | 1848867771892367360 |
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| author | Liew, Ngoh Chin Lee, Limi Ahmad Zaidi, Ahmad Al-Hafeez Teoh, Yan Jun |
| author_facet | Liew, Ngoh Chin Lee, Limi Ahmad Zaidi, Ahmad Al-Hafeez Teoh, Yan Jun |
| author_sort | Liew, Ngoh Chin |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Introduction: Caprini risk assessment model (RAM) has been validated in Caucasians but evidence of its suitability in Asian surgical patients is still unknown. This study aims to determine the efficacy of Caprini model in venous thromboembolism (VTE) risk assessment among Asian surgical patients. Materials and Methods: Consecutive surgical patients with Asian ethnicities admitted to a tertiary public hospital between January 2013 and December 2014, were included. Their demographic details, VTE risk factors and scores based on Caprini RAM were recorded. Primary outcome of this study was symptomatic VTE within 90 days of hospitalisation. Fisher’s exact test and Lasso regression were performed for statistical analysis. Results: A total of 4206 patients were included in this study. Distribution of this study population by risk level was very low, 14.7%; low, 44.1%; moderate, 25.6% and high, 15.7%. The overall symptomatic VTE incidence within 90 days was 0.5%. The incidence of deep venous thrombosis (DVT), pulmonary embolism (PE) and both was 0.31%, 0.19% and 0.05% respectively. VTE incidence by risk category was very low, 0%; low, 0.16%; moderate, 0.37% and high, 2.12%. Obesity (BMI >25), history of prior major surgery, history of DVT/PE and high-risk category (scores ≥5) were significant VTE factors with odds ratio > 5.0. Following the Caprini RAM with ACCP preventive recommendations, an estimated 85% of surgical patients would need prophylaxis. Conclusion: The overall VTE incidence among Asian surgical patients is low. Prophylaxis using Caprini RAM may subject a low incidence patient population to over utilisation of thromboprophylaxis and therefore not cost-effective when applied to Asian patients. |
| first_indexed | 2025-11-15T14:41:48Z |
| format | Article |
| id | upm-118677 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:41:48Z |
| publishDate | 2024 |
| publisher | Malaysian Medical Association |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1186772025-08-05T04:25:26Z http://psasir.upm.edu.my/id/eprint/118677/ Efficacy of Caprini risk assessment model in predicting venous thromboembolism risks among Asian surgical patients Liew, Ngoh Chin Lee, Limi Ahmad Zaidi, Ahmad Al-Hafeez Teoh, Yan Jun Introduction: Caprini risk assessment model (RAM) has been validated in Caucasians but evidence of its suitability in Asian surgical patients is still unknown. This study aims to determine the efficacy of Caprini model in venous thromboembolism (VTE) risk assessment among Asian surgical patients. Materials and Methods: Consecutive surgical patients with Asian ethnicities admitted to a tertiary public hospital between January 2013 and December 2014, were included. Their demographic details, VTE risk factors and scores based on Caprini RAM were recorded. Primary outcome of this study was symptomatic VTE within 90 days of hospitalisation. Fisher’s exact test and Lasso regression were performed for statistical analysis. Results: A total of 4206 patients were included in this study. Distribution of this study population by risk level was very low, 14.7%; low, 44.1%; moderate, 25.6% and high, 15.7%. The overall symptomatic VTE incidence within 90 days was 0.5%. The incidence of deep venous thrombosis (DVT), pulmonary embolism (PE) and both was 0.31%, 0.19% and 0.05% respectively. VTE incidence by risk category was very low, 0%; low, 0.16%; moderate, 0.37% and high, 2.12%. Obesity (BMI >25), history of prior major surgery, history of DVT/PE and high-risk category (scores ≥5) were significant VTE factors with odds ratio > 5.0. Following the Caprini RAM with ACCP preventive recommendations, an estimated 85% of surgical patients would need prophylaxis. Conclusion: The overall VTE incidence among Asian surgical patients is low. Prophylaxis using Caprini RAM may subject a low incidence patient population to over utilisation of thromboprophylaxis and therefore not cost-effective when applied to Asian patients. Malaysian Medical Association 2024 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/118677/1/118677.pdf Liew, Ngoh Chin and Lee, Limi and Ahmad Zaidi, Ahmad Al-Hafeez and Teoh, Yan Jun (2024) Efficacy of Caprini risk assessment model in predicting venous thromboembolism risks among Asian surgical patients. Medical Journal of Malaysia, 79 (3). pp. 320-325. ISSN 0300-5283 https://www.e-mjm.org/2024/v79n3/index.html |
| spellingShingle | Liew, Ngoh Chin Lee, Limi Ahmad Zaidi, Ahmad Al-Hafeez Teoh, Yan Jun Efficacy of Caprini risk assessment model in predicting venous thromboembolism risks among Asian surgical patients |
| title | Efficacy of Caprini risk assessment model in predicting venous thromboembolism risks among Asian surgical patients |
| title_full | Efficacy of Caprini risk assessment model in predicting venous thromboembolism risks among Asian surgical patients |
| title_fullStr | Efficacy of Caprini risk assessment model in predicting venous thromboembolism risks among Asian surgical patients |
| title_full_unstemmed | Efficacy of Caprini risk assessment model in predicting venous thromboembolism risks among Asian surgical patients |
| title_short | Efficacy of Caprini risk assessment model in predicting venous thromboembolism risks among Asian surgical patients |
| title_sort | efficacy of caprini risk assessment model in predicting venous thromboembolism risks among asian surgical patients |
| url | http://psasir.upm.edu.my/id/eprint/118677/ http://psasir.upm.edu.my/id/eprint/118677/ http://psasir.upm.edu.my/id/eprint/118677/1/118677.pdf |