Quantifying myelin in neonates using magnetic resonance imaging: a systematic literature review
This review aimed to assess the usefulness of various magnetic resonance imaging (MRI) techniques for the quantification of neonatal white matter myelination. The Scopus, PubMed, and Web of Science databases were searched to identify studies following the PRISMA (preferred reporting items for system...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Korean Pediatric Society
2023
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| Online Access: | http://psasir.upm.edu.my/id/eprint/118425/ http://psasir.upm.edu.my/id/eprint/118425/1/118425.pdf |
| Summary: | This review aimed to assess the usefulness of various magnetic resonance imaging (MRI) techniques for the quantification of neonatal white matter myelination. The Scopus, PubMed, and Web of Science databases were searched to identify studies following the PRISMA (preferred reporting items for systematic reviews and metaanalyses) statement using quantitative MRI techniques to examine samples collected from neonates to quantify myelin.Twelve studieswereultimately included.The results demonstrated that in validation studies, relaxometry is the most frequently explored approach (83.33%), followed by magnetization transfer imaging (8.33%) and a new automatic segmentation technique (8.33%). Synthetic MRI is recommended for quantifying myelin in neonates because of several advantages that outweigh a few negligible limitations. |
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