Physical and biochemical toxicity assessment of acute lead nitrate (Pb(NO3)2) exposure on liver tissues of Clarias gariepinus
Lead pollution is a major global concern due to its harmful effects on the environment and human health, particularly within the aquaculture industry. This study examines the impact of lead exposure on Clarias gariepinus, a commercially significant catfish species used as a biomarker for environment...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Hibiscus Publisher Enterprise
2024
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/118232/ http://psasir.upm.edu.my/id/eprint/118232/1/118232.pdf |
| _version_ | 1848867465641066496 |
|---|---|
| author | Basirun, Ain Aqilah Md Isa, Fatin Maherah Abdul Wahab Sha’arani, Shakirah Yasid, Nur Adeela |
| author_facet | Basirun, Ain Aqilah Md Isa, Fatin Maherah Abdul Wahab Sha’arani, Shakirah Yasid, Nur Adeela |
| author_sort | Basirun, Ain Aqilah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Lead pollution is a major global concern due to its harmful effects on the environment and human health, particularly within the aquaculture industry. This study examines the impact of lead exposure on Clarias gariepinus, a commercially significant catfish species used as a biomarker for environmental pollution. Lead exposure can disrupt enzyme activity, causing hematological, gastrointestinal, and neurological issues in both humans and animals. The research involved exposing C. gariepinus to varying concentrations of lead nitrate (Pb(NO 3) 2) and assessing behavioral, morphological, and physiological changes. This study revealed dose- dependent impairments in swimming, breathing, and feeding behaviors, highlighting the effect of lead exposure. Histological analysis of liver tissues showed cellular stress and damage, including vacuolization and mitochondrial irregularities. Additionally, the study measured cholinesterase (ChE) activity to assess the biochemical impact on liver function, noting a significant decrease of up to 40% in butyrylcholinesterase (BChE) activity with increased lead exposure. This supports the use of ChE activity as a potential biomarker for environmental pollution. Employing sentinel species like C. gariepinus in environmental risk assessments is crucial. |
| first_indexed | 2025-11-15T14:36:56Z |
| format | Article |
| id | upm-118232 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:36:56Z |
| publishDate | 2024 |
| publisher | Hibiscus Publisher Enterprise |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1182322025-07-01T07:19:17Z http://psasir.upm.edu.my/id/eprint/118232/ Physical and biochemical toxicity assessment of acute lead nitrate (Pb(NO3)2) exposure on liver tissues of Clarias gariepinus Basirun, Ain Aqilah Md Isa, Fatin Maherah Abdul Wahab Sha’arani, Shakirah Yasid, Nur Adeela Lead pollution is a major global concern due to its harmful effects on the environment and human health, particularly within the aquaculture industry. This study examines the impact of lead exposure on Clarias gariepinus, a commercially significant catfish species used as a biomarker for environmental pollution. Lead exposure can disrupt enzyme activity, causing hematological, gastrointestinal, and neurological issues in both humans and animals. The research involved exposing C. gariepinus to varying concentrations of lead nitrate (Pb(NO 3) 2) and assessing behavioral, morphological, and physiological changes. This study revealed dose- dependent impairments in swimming, breathing, and feeding behaviors, highlighting the effect of lead exposure. Histological analysis of liver tissues showed cellular stress and damage, including vacuolization and mitochondrial irregularities. Additionally, the study measured cholinesterase (ChE) activity to assess the biochemical impact on liver function, noting a significant decrease of up to 40% in butyrylcholinesterase (BChE) activity with increased lead exposure. This supports the use of ChE activity as a potential biomarker for environmental pollution. Employing sentinel species like C. gariepinus in environmental risk assessments is crucial. Hibiscus Publisher Enterprise 2024-07-31 Article PeerReviewed text en cc_by_4 http://psasir.upm.edu.my/id/eprint/118232/1/118232.pdf Basirun, Ain Aqilah and Md Isa, Fatin Maherah and Abdul Wahab Sha’arani, Shakirah and Yasid, Nur Adeela (2024) Physical and biochemical toxicity assessment of acute lead nitrate (Pb(NO3)2) exposure on liver tissues of Clarias gariepinus. Journal of Environmental Microbiology and Toxicology, 12 (2). pp. 14-22. ISSN 2289-5906 https://journal.hibiscuspublisher.com/index.php/JEMAT/article/view/1000 10.54987/jemat.v12i1.1000 |
| spellingShingle | Basirun, Ain Aqilah Md Isa, Fatin Maherah Abdul Wahab Sha’arani, Shakirah Yasid, Nur Adeela Physical and biochemical toxicity assessment of acute lead nitrate (Pb(NO3)2) exposure on liver tissues of Clarias gariepinus |
| title | Physical and biochemical toxicity assessment of acute lead nitrate (Pb(NO3)2) exposure on liver tissues of Clarias gariepinus |
| title_full | Physical and biochemical toxicity assessment of acute lead nitrate (Pb(NO3)2) exposure on liver tissues of Clarias gariepinus |
| title_fullStr | Physical and biochemical toxicity assessment of acute lead nitrate (Pb(NO3)2) exposure on liver tissues of Clarias gariepinus |
| title_full_unstemmed | Physical and biochemical toxicity assessment of acute lead nitrate (Pb(NO3)2) exposure on liver tissues of Clarias gariepinus |
| title_short | Physical and biochemical toxicity assessment of acute lead nitrate (Pb(NO3)2) exposure on liver tissues of Clarias gariepinus |
| title_sort | physical and biochemical toxicity assessment of acute lead nitrate (pb(no3)2) exposure on liver tissues of clarias gariepinus |
| url | http://psasir.upm.edu.my/id/eprint/118232/ http://psasir.upm.edu.my/id/eprint/118232/ http://psasir.upm.edu.my/id/eprint/118232/ http://psasir.upm.edu.my/id/eprint/118232/1/118232.pdf |