Extraosseous Ewing sarcoma of pancreas: a rare entity
Ewing sarcoma is a rare type of cancer that typically arises in the bones or soft tissues of children and young adults. However, Ewing sarcoma can also occur in other body parts, including the pancreas. Ewing sarcoma of the pancreas is rare and often affects children or young adults. We reported a 3...
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| Format: | Article |
| Language: | English |
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Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
2024
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| Online Access: | http://psasir.upm.edu.my/id/eprint/118196/ http://psasir.upm.edu.my/id/eprint/118196/1/118196.pdf |
| _version_ | 1848867455977390080 |
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| author | Abdullah, Maizaton Atmadini Abd Ghani, Fauzah Mohamed Shabery, Noor Afidah Sulaiman, Nor Akmar |
| author_facet | Abdullah, Maizaton Atmadini Abd Ghani, Fauzah Mohamed Shabery, Noor Afidah Sulaiman, Nor Akmar |
| author_sort | Abdullah, Maizaton Atmadini |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Ewing sarcoma is a rare type of cancer that typically arises in the bones or soft tissues of children and young adults. However, Ewing sarcoma can also occur in other body parts, including the pancreas. Ewing sarcoma of the pancreas is rare and often affects children or young adults. We reported a 33-year-old male with no medical illness who presented with worsening epigastric pain and vomiting for one-week duration. CT scan of the abdomen showed an obstructive duodenal mass complicated with perforation. The biopsy of the duodenal mass showed sheets of small round blue cells with immunohistochemical features favouring Ewing sarcoma. Pancreatoduodenectomy procedure (Whipple resection) was performed, which revealed an ill-defined whitish solid tumour at the head of the pancreas measuring 80x50x65mm. Histologically, the tumour is composed of sheets of malignant cells displaying uniform small round to oval nuclei containing fine chromatin, inconspicuous nucleoli, scanty cytoplasm, and indistinct cell membrane. A few mitoses are seen (4/10HPF). Areas of tumour necrosis are observed. Scattered lymphovascular invasion is also present. The malignant cells are infiltrating into the duodenal mucosa. The malignant cells are diffuse and strongly positive towards CD99, FLI-1 and NK2.2 (Figure 3). A diagnosis of primary pancreatic Ewing sarcoma was made. |
| first_indexed | 2025-11-15T14:36:47Z |
| format | Article |
| id | upm-118196 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:36:47Z |
| publishDate | 2024 |
| publisher | Faculty of Medicine and Health Sciences, Universiti Putra Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1181962025-06-30T02:51:52Z http://psasir.upm.edu.my/id/eprint/118196/ Extraosseous Ewing sarcoma of pancreas: a rare entity Abdullah, Maizaton Atmadini Abd Ghani, Fauzah Mohamed Shabery, Noor Afidah Sulaiman, Nor Akmar Ewing sarcoma is a rare type of cancer that typically arises in the bones or soft tissues of children and young adults. However, Ewing sarcoma can also occur in other body parts, including the pancreas. Ewing sarcoma of the pancreas is rare and often affects children or young adults. We reported a 33-year-old male with no medical illness who presented with worsening epigastric pain and vomiting for one-week duration. CT scan of the abdomen showed an obstructive duodenal mass complicated with perforation. The biopsy of the duodenal mass showed sheets of small round blue cells with immunohistochemical features favouring Ewing sarcoma. Pancreatoduodenectomy procedure (Whipple resection) was performed, which revealed an ill-defined whitish solid tumour at the head of the pancreas measuring 80x50x65mm. Histologically, the tumour is composed of sheets of malignant cells displaying uniform small round to oval nuclei containing fine chromatin, inconspicuous nucleoli, scanty cytoplasm, and indistinct cell membrane. A few mitoses are seen (4/10HPF). Areas of tumour necrosis are observed. Scattered lymphovascular invasion is also present. The malignant cells are infiltrating into the duodenal mucosa. The malignant cells are diffuse and strongly positive towards CD99, FLI-1 and NK2.2 (Figure 3). A diagnosis of primary pancreatic Ewing sarcoma was made. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2024 Article PeerReviewed text en cc_by_4 http://psasir.upm.edu.my/id/eprint/118196/1/118196.pdf Abdullah, Maizaton Atmadini and Abd Ghani, Fauzah and Mohamed Shabery, Noor Afidah and Sulaiman, Nor Akmar (2024) Extraosseous Ewing sarcoma of pancreas: a rare entity. Malaysian Journal of Medicine and Health Sciences, 20 (suppl.11). pp. 146-149. ISSN 1675-8544; eISSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2025010610580432_MJMHS_1070.pdf |
| spellingShingle | Abdullah, Maizaton Atmadini Abd Ghani, Fauzah Mohamed Shabery, Noor Afidah Sulaiman, Nor Akmar Extraosseous Ewing sarcoma of pancreas: a rare entity |
| title | Extraosseous Ewing sarcoma of pancreas: a rare entity |
| title_full | Extraosseous Ewing sarcoma of pancreas: a rare entity |
| title_fullStr | Extraosseous Ewing sarcoma of pancreas: a rare entity |
| title_full_unstemmed | Extraosseous Ewing sarcoma of pancreas: a rare entity |
| title_short | Extraosseous Ewing sarcoma of pancreas: a rare entity |
| title_sort | extraosseous ewing sarcoma of pancreas: a rare entity |
| url | http://psasir.upm.edu.my/id/eprint/118196/ http://psasir.upm.edu.my/id/eprint/118196/ http://psasir.upm.edu.my/id/eprint/118196/1/118196.pdf |