Potential impacts of Covid-19 on autoimmune diseases: a case report on Systemic Sclerosis
Systemic sclerosis (SSc) is a rare autoimmune disease characterised by fibrosis of the skin, musculoskeletal system and internal organs, with clinical presentations ranging from rapidly progressive to chronic forms. The Covid-19 pandemic has highlighted potential links between infections and autoimm...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Universiti Putra Malaysia
2024
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/118124/ http://psasir.upm.edu.my/id/eprint/118124/1/118124.pdf |
| _version_ | 1848867437356777472 |
|---|---|
| author | Mahayidin, Hasni Jamalut, Yusanita Zaini, Adilahtul Bushro |
| author_facet | Mahayidin, Hasni Jamalut, Yusanita Zaini, Adilahtul Bushro |
| author_sort | Mahayidin, Hasni |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Systemic sclerosis (SSc) is a rare autoimmune disease characterised by fibrosis of the skin, musculoskeletal system and internal organs, with clinical presentations ranging from rapidly progressive to chronic forms. The Covid-19 pandemic has highlighted potential links between infections and autoimmune diseases. We report a 49-year-old female with a history of Covid-19 reinfection who presented with long Covid symptoms. She was discovered to have a five-year history of multiple joint pain and recently developed bilateral swollen fingers with distal skin thickening extending to the elbows. Investigations revealed strong ANA and anti-Scl-70 positivity while CT thorax showed features of autoimmune interstitial lung disease. She was diagnosed to have long Covid with limited cutaneous SSc. Although the link between Covid-19 and SSc remains unclear, this case underscores the potential impacts of Covid-19 on pre-existing autoimmune diseases, including acceleration of disease progression, overlapping of symptoms and increased diagnostic rates due to heightened health awareness. |
| first_indexed | 2025-11-15T14:36:29Z |
| format | Article |
| id | upm-118124 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:36:29Z |
| publishDate | 2024 |
| publisher | Universiti Putra Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1181242025-06-25T03:43:05Z http://psasir.upm.edu.my/id/eprint/118124/ Potential impacts of Covid-19 on autoimmune diseases: a case report on Systemic Sclerosis Mahayidin, Hasni Jamalut, Yusanita Zaini, Adilahtul Bushro Systemic sclerosis (SSc) is a rare autoimmune disease characterised by fibrosis of the skin, musculoskeletal system and internal organs, with clinical presentations ranging from rapidly progressive to chronic forms. The Covid-19 pandemic has highlighted potential links between infections and autoimmune diseases. We report a 49-year-old female with a history of Covid-19 reinfection who presented with long Covid symptoms. She was discovered to have a five-year history of multiple joint pain and recently developed bilateral swollen fingers with distal skin thickening extending to the elbows. Investigations revealed strong ANA and anti-Scl-70 positivity while CT thorax showed features of autoimmune interstitial lung disease. She was diagnosed to have long Covid with limited cutaneous SSc. Although the link between Covid-19 and SSc remains unclear, this case underscores the potential impacts of Covid-19 on pre-existing autoimmune diseases, including acceleration of disease progression, overlapping of symptoms and increased diagnostic rates due to heightened health awareness. Universiti Putra Malaysia 2024 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/118124/1/118124.pdf Mahayidin, Hasni and Jamalut, Yusanita and Zaini, Adilahtul Bushro (2024) Potential impacts of Covid-19 on autoimmune diseases: a case report on Systemic Sclerosis. Malaysian Journal of Medicine and Health Sciences, 20 (suppl.11). pp. 129-133. ISSN 1675-8544; eISSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2024123018405228_MJMHS_1551.pdf 10.47836/mjmhs.20.s11.28 |
| spellingShingle | Mahayidin, Hasni Jamalut, Yusanita Zaini, Adilahtul Bushro Potential impacts of Covid-19 on autoimmune diseases: a case report on Systemic Sclerosis |
| title | Potential impacts of Covid-19 on autoimmune diseases: a case report on Systemic Sclerosis |
| title_full | Potential impacts of Covid-19 on autoimmune diseases: a case report on Systemic Sclerosis |
| title_fullStr | Potential impacts of Covid-19 on autoimmune diseases: a case report on Systemic Sclerosis |
| title_full_unstemmed | Potential impacts of Covid-19 on autoimmune diseases: a case report on Systemic Sclerosis |
| title_short | Potential impacts of Covid-19 on autoimmune diseases: a case report on Systemic Sclerosis |
| title_sort | potential impacts of covid-19 on autoimmune diseases: a case report on systemic sclerosis |
| url | http://psasir.upm.edu.my/id/eprint/118124/ http://psasir.upm.edu.my/id/eprint/118124/ http://psasir.upm.edu.my/id/eprint/118124/ http://psasir.upm.edu.my/id/eprint/118124/1/118124.pdf |