Synergistic effects of Gefitinib and Paclitaxel in breast cancer treatment using cockle shell-derived nanoparticle

QR Code

Synergistic effects of Gefitinib and Paclitaxel in breast cancer treatment using cockle shell-derived nanoparticle

Breast cancer is the most common type of cancer in women worldwide, including in Malaysia, ranking second in terms of mortality rate. The problem with conventional chemotherapy and radiotherapy is that they also elicit adverse effects on healthy cells. Nowadays, nanoparticle-based drug carriers and...

Full description

Bibliographic Details
Main Author:	Chemmalar, Sangaran
Format:	Thesis
Language:	English
Published:	2023
Subjects:	Breast Neoplasms - Drug therapy Nanoparticles (Pharmacology) Drug Synergism
Online Access:	http://psasir.upm.edu.my/id/eprint/118108/ http://psasir.upm.edu.my/id/eprint/118108/1/118108.pdf

Similar Items

Vitamin D3-associated lyotropic liquid crystalline nanoparticles for gemcitabine and thymoquinone delivery for treatment of luminal breast cancer with resistant characteristics
by: Loo, Yan Shan
Published: (2023)

Enhancement of in vitro effects of polymeric nanoparticle encapsulated tamoxifin compared to tamoxifen in MCF-7 breast cancer cell line
by: Tung, En En
Published: (2012)

An apoferritin-based drug delivery system for the tyrosine kinase inhibitor gefitinib
by: Kuruppu, Anchala I., et al.
Published: (2015)

Antioxidant and phytochemical properties and in vitro cancer chemopreventive effects of averrhoa bilimbi l. extract on human breast and cervical adenocarcinoma
by: Yan, See Wan
Published: (2012)

Synthesis and characterization of gefitinib and paclitaxel mono and dual drug-loaded blood cockle shells (Anadara granosa)-derived aragonite CaCO3 nanoparticles
by: Chemmalar, S., et al.
Published: (2021)

Identification and characterisation of single nucleotide polymorphisms in cytochrome P450 2D6 gene in Malaysian breast cancer patients
by: Chin, Fee Wai
Published: (2012)

Cost of cancer care for patients undergoing chemotherapy: The Elements of Cancer Care study
by: Ward, R., et al.
Published: (2015)

Prevalence and predictors of depression and anxiety among oncology patients receiving chemotherapy in public hospitals in Peninsular Malaysia
by: Remesh Kumar, Mamta Vesudave
Published: (2018)

An unusual synergistic adsorption of MIBC and CTAB mixtures at the air–water interface
by: Le, Ngoc Thu, et al.
Published: (2012)

Suppression Effects of Pandanus Amarylfolius and Strobilanthes Cripus Extracts on the Growth of Breast Cancer Cells by Inducing p53-Mediated Apoptotic Pathway
by: Chong, Hueh Zan
Published: (2010)

Histological and safety evaluation of cockle shell-derived CaCO₃ nanoparticle loaded with doxorubicin in dogs
by: Abubakar, Danmaigoro
Published: (2018)

Formulation of chitosan-based nanoparticles for delivery of proteins and peptides
by: Vellore Janarthanan, Mohanraj
Published: (2003)

Rational engineering of Apoferritin-based nanoparticles for drug delivery
by: Crowhurst, Samuel
Published: (2025)

Improving Nanoparticle Drug loading: Matching Polymer to Drug Properties and making of Polymer coated Drug Nanoparticles
by: ANIMASAWUN, R.K
Published: (2020)

Evaluation of pancreatic cancer cell lines as a source of cancer stem cells (CSC) and their utilisation for assessing anti-CSC activities of KRAS binders
by: Teh, Yuan Han
Published: (2020)

Anti-arthritic effects of 6-mercaptopurine and its derivatives in arthritis-induced model, In vitro and In vivo
by: Che Ku Daud, Che Ku Dahlan
Published: (2020)

Novel functionalized polymers for nanoparticle formulations with anti cancer drugs
by: Puri, Sanyogitta
Published: (2007)

In vitro antiproliferative effects and underlying mechanismds of bismuth dithiocarbamate derivatives against breast cancer cell line
by: Chan, Pit Foong
Published: (2019)

Functional Characterization of Calreticulin in Invasive Human Breast Cancer
by: Zamanian, Mohammedreza
Published: (2011)

Anti-breast cancer effect of eupatorin in vitro and in vivo
by: Abd Razak, Nursyamirah
Published: (2018)

Development and in vitro bioevaluation of cockle shell-calcium carbonate (Aragonite) nanoparticles for intracellular drug delivery
by: Isa, Tijani
Published: (2015)

Application of Proteomics Approaches in the Identification of New Markers and Therapeutic Targets for Breast Cancer
by: Moh’d Hamadneh, Lama Abdel Qader
Published: (2008)

Polymorphisms in Estrogen Receptor-Α and -Β Genes and Their Correlations with Risk Factors in Iranian Breast Cancer Patients
by: Abbasi, Sakineh
Published: (2009)

Identification and analysis of single nucleotide polymorphisms in matrix metallopeptidase 2 and 3 genes in Malaysian breast cancer patients
by: Chan, Soon Choy
Published: (2013)

Synthesis and in-vitro toxicity evaluation of anticancer drugs-loaded chitosan nanoparticles as therapeutic nanocarriers for the treatment of hepatocellular carcinoma
by: Mohammed, Albalawi Fahad
Published: (2023)

Weight Change and its Related Factors Among Women after Breast Cancer Diagnosis in Selected Hospitals in Peninsular Malaysia
by: Yong, Heng Yaw
Published: (2011)

Localization of Newcastle Disease Virus (Ndv-Af2240) in 4T1 Xenotransplant Breast Cancer Balb/C Mice
by: Motalleb, Gholamreza
Published: (2009)

Developing a sprayable drug delivery system for the local delivery of nanoparticles in glioblastoma multiforme
by: McCrorie, Phoebe
Published: (2021)

Development of nanoparticles for targeted delivery of p38 MAPK inhibitor to myeloid dendritic cells
by: You, Jinge
Published: (2024)

Functionalized ionic-liquid templated mesoporous silica nanoparticles for anticancer drug delivery system
by: Zaharudin, Nurul Syahira
Published: (2018)

Psychological distress and associated personal and workplace stressors among breast cancer survivors
by: Yong, Heng Weay
Published: (2012)

Dissecting the potential role of calreticulin as a prognostic biomarker for invasive breast cancer
by: Mehdi, Sabaghpour Azarian Mohammad
Published: (2020)

Development of a drug delivery agent based on ionic liquids templated mesoporous silica nanoparticles
by: Mohamed Isa, Eleen Dayana
Published: (2017)

Characterization, histological evaluation and efficacy of docetaxel-loaded cockle shellderived CaCO3 nanoparticles in vitro and in vivo
by: Hammadi, Nahidah Ibrahim
Published: (2018)

Cytotoxic properties of phosphinegold (I) dithiocarbamates on breast carcinoma cell line MCF-7
by: Goh, Zheng Jie
Published: (2017)

Molecular modelling of berberine derivatives as inhibitors of oncogenic signalling pathways in breast cancer cell lines
by: Kaboli, Parham Jabbarzadeh
Published: (2017)

Engineering apoferritin for targeted delivery of peptides or proteins for the treatment of breast cancer
by: Ferreira, Lenny
Published: (2023)

PEGylation of paclitaxel for inhaled chemotherapy
by: Luo, Tian
Published: (2016)

Factors affecting recruitment to breast cancer clinical trials: an examination of the British Association of Surgical Oncology II trial and the International Breast Cancer Intervention Study
by: Maslin-Prothero, Sian
Published: (2000)

Choline as a molecular imaging biomarker for assessing breast cancer aggressiveness
by: Shaharuddin, Shazreen
Published: (2017)