PARP inhibitor combinations with Olaparib for synergistic efficacy in Olaparib-resistant triple-negative breast cancer cells
Triple-negative breast cancer (TNBC) is associated with aggressive and heterogenous tumour phenotype, early tumour relapse and poor prognosis than other types of invasive breast cancer. TNBC does not respond to endocrine therapy due to the lack of oestrogen receptor (ER), progesterone receptor (P...
| Main Author: | Yusoh, Nur Aininie |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
2023
|
| Subjects: | |
| Online Access: | http://psasir.upm.edu.my/id/eprint/118100/ http://psasir.upm.edu.my/id/eprint/118100/1/118100.pdf |
Similar Items
Phase I trial of the oral PARP inhibitor olaparib in combination with paclitaxel for first- or second-line treatment of patients with metastatic triple-negative breast cancer
by: Dent, R., et al.
Published: (2013)
by: Dent, R., et al.
Published: (2013)
Synergy of ruthenium metallo-intercalator, [Ru(dppz)2(PIP)]2+, with PARP inhibitor Olaparib in non-small cell lung cancer cells
by: Yusoh, Nur Aininie, et al.
Published: (2023)
by: Yusoh, Nur Aininie, et al.
Published: (2023)
Efficacy of RNA polymerase II inhibitors in targeting dormant leukaemia cells
by: Pallis, Monica, et al.
Published: (2013)
by: Pallis, Monica, et al.
Published: (2013)
Discovery of ruthenium(ii) metallocompound and olaparib synergy for cancer combination therapy
by: Yusoh, Nur Aininie, et al.
Published: (2023)
by: Yusoh, Nur Aininie, et al.
Published: (2023)
Investigations of bioresponsive polymers in triple negative breast cancers
by: Monteiro, Patricia
Published: (2019)
by: Monteiro, Patricia
Published: (2019)
Effects of bortezomib on HIF-1 and HIF-2 transcriptional activities
by: Abd Aziz, Noraini
Published: (2013)
by: Abd Aziz, Noraini
Published: (2013)
The calpain system is associated with survival of breast cancer patients with large but operable inflammatory and non-inflammatory tumours treated with neoadjuvant chemotherapy
by: Storr, Sarah J., et al.
Published: (2016)
by: Storr, Sarah J., et al.
Published: (2016)
The role of calpain/calpastatin in breast cancer
by: Cook, Liam
Published: (2024)
by: Cook, Liam
Published: (2024)
Metallointercalator [Ru(dppz)2(PIP)]2+ renders BRCA wild-type triple-negative breast cancer cells hypersensitive to PARP inhibition
by: Yusoh, Nur Aininie, et al.
Published: (2020)
by: Yusoh, Nur Aininie, et al.
Published: (2020)
The role of HOXA5 in triple-negative breast cancer (TNBC)
by: Mahmoud, Rinad
Published: (2021)
by: Mahmoud, Rinad
Published: (2021)
Characterization, histological evaluation and efficacy of docetaxel-loaded cockle shellderived CaCO3 nanoparticles in vitro and in vivo
by: Hammadi, Nahidah Ibrahim
Published: (2018)
by: Hammadi, Nahidah Ibrahim
Published: (2018)
Passerini multicomponent reaction: a versatile synthesis of nanomedicines for triple negative breast cancer treatment
by: Travanut, Alessandra
Published: (2021)
by: Travanut, Alessandra
Published: (2021)
Effect of combination therapy of ruthenium polypyridyl complex, [Ru(dppz)2(PIP)]2+ and parp inhibitors against several cancer cell lines
by: Yusoh, Nur Aininie
Published: (2020)
by: Yusoh, Nur Aininie
Published: (2020)
In vitro treatment of MCF-7 and MDA-MB-231 breast cancer cell lines with doxorubicin and vincristine sulphate calcium carbonate nanoparticles
by: Mengyi, Xue
Published: (2019)
by: Mengyi, Xue
Published: (2019)
Integrative molecular and pathologic profiling of triple negative breast cancer
by: Alsaleem, Mansour
Published: (2021)
by: Alsaleem, Mansour
Published: (2021)
The prognostic and predictive power of redox rotein expression for anthracycline-based chemotherapy response in locally advanced breast cancer
by: Woolston, Caroline M., et al.
Published: (2012)
by: Woolston, Caroline M., et al.
Published: (2012)
Effects of ampelopsin E towards the invasiveness of triple negative breast cancer cell line, MDA-MB-231
by: Tieng, Francis Yew Fu
Published: (2019)
by: Tieng, Francis Yew Fu
Published: (2019)
Controversial issues in the management of older adults with early breast cancer
by: Mislang, Anna Rachelle, et al.
Published: (2017)
by: Mislang, Anna Rachelle, et al.
Published: (2017)
The identification of targeting peptides and tumour associated antigens for the treatment and early detection of triple negative breast cancer
by: Wilde, Megan
Published: (2023)
by: Wilde, Megan
Published: (2023)
The relationship of CDK18 expression in breast cancer to clinicopathological parameters and therapeutic response
by: Barone, Giancarlo, et al.
Published: (2018)
by: Barone, Giancarlo, et al.
Published: (2018)
The role of sodium driven bicarbonate transporters in triple negative breast cancer metastasis
by: Carroll, Christopher
Published: (2020)
by: Carroll, Christopher
Published: (2020)
Profiling of gene and exosomal microRNA as therapy targets and biomarkers of cisplatin resistance in triple negative breast cancer stem cell-like subpopulation
by: Koh, May Zie
Published: (2021)
by: Koh, May Zie
Published: (2021)
Molecular cloning, functional assessment and transcriptome characterization of cysteine protease inhibitor and kunitz trypsin inhibitor from turmeric (Curcuma longa L.)
by: Chan, Seow Neng
Published: (2016)
by: Chan, Seow Neng
Published: (2016)
Double major ADP programme at SEGi
Published: (2010)
Published: (2010)
Identification of lipase inhibitor from orthosiphon stamineus benth and analysis of lipase-inhibitor complex interaction
by: Alias, Norsyuhada
Published: (2016)
by: Alias, Norsyuhada
Published: (2016)
Combining PARP inhibition with platinum, ruthenium or gold complexes for cancer therapy
by: Yusoh, Nur Aininie, et al.
Published: (2020)
by: Yusoh, Nur Aininie, et al.
Published: (2020)
Molecular characterization of horseshoe crab anti-lipopolysaccharide factor C-peptide for hybridization-based detection method of gram negative bacteria.
by: Abdullah Al-Haj, Nagi Ahmed, et al.
Published: (2008)
by: Abdullah Al-Haj, Nagi Ahmed, et al.
Published: (2008)
Quality of life among breast cancer
patients undergoing chemotherapy in
Oncology Unit at Hospital Universiti Sains
Malaysia
by: Azman, Wan Nur Atirah Wan
Published: (2013)
by: Azman, Wan Nur Atirah Wan
Published: (2013)
Development of a stable T7 RNA polymerase expressing cell line using a lentivirus system
by: Yeong, Ming Yue
Published: (2019)
by: Yeong, Ming Yue
Published: (2019)
The role of polymeric immunoglobulin receptor in breast cancer
by: Asanprakit, Wichitra
Published: (2021)
by: Asanprakit, Wichitra
Published: (2021)
Anti-breast cancer effect of eupatorin in vitro and in vivo
by: Abd Razak, Nursyamirah
Published: (2018)
by: Abd Razak, Nursyamirah
Published: (2018)
Synergistic effects of Gefitinib and Paclitaxel in breast cancer treatment using cockle shell-derived nanoparticle
by: Chemmalar, Sangaran
Published: (2023)
by: Chemmalar, Sangaran
Published: (2023)
Wnt signaling in triple-negative breast cancer
by: Pohl, S., et al.
Published: (2017)
by: Pohl, S., et al.
Published: (2017)
Molecular modelling of berberine derivatives as inhibitors of oncogenic signalling pathways in breast cancer cell lines
by: Kaboli, Parham Jabbarzadeh
Published: (2017)
by: Kaboli, Parham Jabbarzadeh
Published: (2017)
Can an inhibitor of a multidrug pump become a substrate?
by: Hutchison, Ella
Published: (2022)
by: Hutchison, Ella
Published: (2022)
Optimisation of treatment of cancer based on principles of pharmacokinetics
by: Lee, Jong Bong
Published: (2018)
by: Lee, Jong Bong
Published: (2018)
Neuraminidase inhibitors: who, when, where?
by: Nguyen-Van-Tam, Jonathan S., et al.
Published: (2015)
by: Nguyen-Van-Tam, Jonathan S., et al.
Published: (2015)
The association of ICAM-1 detected by immunohistochemical staining with triple negative and non-triple negative breast carcinoma
by: Chong, Choi Yen, et al.
Published: (2019)
by: Chong, Choi Yen, et al.
Published: (2019)
Tumour-draining axillary lymph nodes in patients with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC): the crucial contribution of immune cells (effector, regulatory) and cytokines (TH1, TH2) to immune-mediated tumour cell death induced by NAC
by: Kaewkangsadan, Viriya, et al.
Published: (2016)
by: Kaewkangsadan, Viriya, et al.
Published: (2016)
Tumour-draining axillary lymph nodes in patients with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC): the crucial contribution of immune cells (effector, regulatory) and cytokines (TH1, TH2) to immune-mediated tumour cell death induced by NAC
by: Kaewkangsadan, Viriya, et al.
Published: (2018)
by: Kaewkangsadan, Viriya, et al.
Published: (2018)
Similar Items
-
Phase I trial of the oral PARP inhibitor olaparib in combination with paclitaxel for first- or second-line treatment of patients with metastatic triple-negative breast cancer
by: Dent, R., et al.
Published: (2013) -
Synergy of ruthenium metallo-intercalator, [Ru(dppz)2(PIP)]2+, with PARP inhibitor Olaparib in non-small cell lung cancer cells
by: Yusoh, Nur Aininie, et al.
Published: (2023) -
Efficacy of RNA polymerase II inhibitors in targeting dormant leukaemia cells
by: Pallis, Monica, et al.
Published: (2013) -
Discovery of ruthenium(ii) metallocompound and olaparib synergy for cancer combination therapy
by: Yusoh, Nur Aininie, et al.
Published: (2023) -
Investigations of bioresponsive polymers in triple negative breast cancers
by: Monteiro, Patricia
Published: (2019)