Epstein-Barr virus-associated smooth muscle tumour: two case reports
Epstein-Barr virus-associated smooth muscle tumour (EBV-SMT) is an intermediate mesenchymal neoplasm recognised in immunocompromised patients, including HIV-infected patients. EBV-SMT is challenging to diagnose since it occurs in various age groups and anatomical sites and presents with nonspecific...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
2024
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| Online Access: | http://psasir.upm.edu.my/id/eprint/117973/ http://psasir.upm.edu.my/id/eprint/117973/1/117973.pdf |
| _version_ | 1848867395118039040 |
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| author | Hussin, Huzlinda Abdul Kahar, Nor Farahin Mohd Dusa, Noraini Abd Rani, Nor Haizura |
| author_facet | Hussin, Huzlinda Abdul Kahar, Nor Farahin Mohd Dusa, Noraini Abd Rani, Nor Haizura |
| author_sort | Hussin, Huzlinda |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Epstein-Barr virus-associated smooth muscle tumour (EBV-SMT) is an intermediate mesenchymal neoplasm recognised in immunocompromised patients, including HIV-infected patients. EBV-SMT is challenging to diagnose since it occurs in various age groups and anatomical sites and presents with nonspecific symptoms. The diagnosis is further complicated by the similarity of its histopathological features with other spindle cell tumours. A clinical history of immunosuppression, immunohistochemistry study and association with Epstein-Barr. virus (EBV) infection can aid in the diagnosis. Here, we reported two cases of EBV-SMT in two patients with HIV infection, emphasising the histomorphology features and immunohistochemical profile that help in the diagnosis. |
| first_indexed | 2025-11-15T14:35:49Z |
| format | Article |
| id | upm-117973 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:35:49Z |
| publishDate | 2024 |
| publisher | Faculty of Medicine and Health Sciences, Universiti Putra Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1179732025-06-18T08:17:04Z http://psasir.upm.edu.my/id/eprint/117973/ Epstein-Barr virus-associated smooth muscle tumour: two case reports Hussin, Huzlinda Abdul Kahar, Nor Farahin Mohd Dusa, Noraini Abd Rani, Nor Haizura Epstein-Barr virus-associated smooth muscle tumour (EBV-SMT) is an intermediate mesenchymal neoplasm recognised in immunocompromised patients, including HIV-infected patients. EBV-SMT is challenging to diagnose since it occurs in various age groups and anatomical sites and presents with nonspecific symptoms. The diagnosis is further complicated by the similarity of its histopathological features with other spindle cell tumours. A clinical history of immunosuppression, immunohistochemistry study and association with Epstein-Barr. virus (EBV) infection can aid in the diagnosis. Here, we reported two cases of EBV-SMT in two patients with HIV infection, emphasising the histomorphology features and immunohistochemical profile that help in the diagnosis. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2024 Article PeerReviewed text en cc_by_4 http://psasir.upm.edu.my/id/eprint/117973/1/117973.pdf Hussin, Huzlinda and Abdul Kahar, Nor Farahin and Mohd Dusa, Noraini and Abd Rani, Nor Haizura (2024) Epstein-Barr virus-associated smooth muscle tumour: two case reports. Malaysian Journal of Medicine and Health Sciences, 20 (suppl.11). pp. 102-105. ISSN 1675-8544; eISSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2024123018333220_MJMHS_1045.pdf |
| spellingShingle | Hussin, Huzlinda Abdul Kahar, Nor Farahin Mohd Dusa, Noraini Abd Rani, Nor Haizura Epstein-Barr virus-associated smooth muscle tumour: two case reports |
| title | Epstein-Barr virus-associated smooth muscle tumour: two case reports |
| title_full | Epstein-Barr virus-associated smooth muscle tumour: two case reports |
| title_fullStr | Epstein-Barr virus-associated smooth muscle tumour: two case reports |
| title_full_unstemmed | Epstein-Barr virus-associated smooth muscle tumour: two case reports |
| title_short | Epstein-Barr virus-associated smooth muscle tumour: two case reports |
| title_sort | epstein-barr virus-associated smooth muscle tumour: two case reports |
| url | http://psasir.upm.edu.my/id/eprint/117973/ http://psasir.upm.edu.my/id/eprint/117973/ http://psasir.upm.edu.my/id/eprint/117973/1/117973.pdf |