Targeting 8-oxoguanine DNA glycosylase-1 (OGG1) as a therapeutic strategy in inflammatory-related diseases
Inflammatory diseases are influenced by oxidative stress. Oxidatively damaged 8-oxoG in DNA is linked to inflammation. The enzyme OGG1 is responsible for repairing the damaged base in the DNA which is linked to pro-inflammatory signaling and severe inflammation. This study aims to explore the potent...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis
2024
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| Online Access: | http://psasir.upm.edu.my/id/eprint/117856/ http://psasir.upm.edu.my/id/eprint/117856/1/117856.pdf |
| _version_ | 1848867361640153088 |
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| author | Samaila, Abdullahi Basir, Rusliza Gambo Lawal, Mukhtar Abas, Razif Abdullah, Maizaton Atmadini Abd Majid, Roslaini Nordin, Norshariza Hussain, Mohd Khairi Ab Razak, Nur Izah Yoke Keong, Yong Aliyu, Basiru |
| author_facet | Samaila, Abdullahi Basir, Rusliza Gambo Lawal, Mukhtar Abas, Razif Abdullah, Maizaton Atmadini Abd Majid, Roslaini Nordin, Norshariza Hussain, Mohd Khairi Ab Razak, Nur Izah Yoke Keong, Yong Aliyu, Basiru |
| author_sort | Samaila, Abdullahi |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Inflammatory diseases are influenced by oxidative stress. Oxidatively damaged 8-oxoG in DNA is linked to inflammation. The enzyme OGG1 is responsible for repairing the damaged base in the DNA which is linked to pro-inflammatory signaling and severe inflammation. This study aims to explore the potential of targeting OGG1 as a therapeutic strategy in inflammatory disease conditions. |
| first_indexed | 2025-11-15T14:35:17Z |
| format | Article |
| id | upm-117856 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:35:17Z |
| publishDate | 2024 |
| publisher | Taylor & Francis |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1178562025-06-13T07:29:02Z http://psasir.upm.edu.my/id/eprint/117856/ Targeting 8-oxoguanine DNA glycosylase-1 (OGG1) as a therapeutic strategy in inflammatory-related diseases Samaila, Abdullahi Basir, Rusliza Gambo Lawal, Mukhtar Abas, Razif Abdullah, Maizaton Atmadini Abd Majid, Roslaini Nordin, Norshariza Hussain, Mohd Khairi Ab Razak, Nur Izah Yoke Keong, Yong Aliyu, Basiru Inflammatory diseases are influenced by oxidative stress. Oxidatively damaged 8-oxoG in DNA is linked to inflammation. The enzyme OGG1 is responsible for repairing the damaged base in the DNA which is linked to pro-inflammatory signaling and severe inflammation. This study aims to explore the potential of targeting OGG1 as a therapeutic strategy in inflammatory disease conditions. Taylor & Francis 2024 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/117856/1/117856.pdf Samaila, Abdullahi and Basir, Rusliza and Gambo Lawal, Mukhtar and Abas, Razif and Abdullah, Maizaton Atmadini and Abd Majid, Roslaini and Nordin, Norshariza and Hussain, Mohd Khairi and Ab Razak, Nur Izah and Yoke Keong, Yong and Aliyu, Basiru (2024) Targeting 8-oxoguanine DNA glycosylase-1 (OGG1) as a therapeutic strategy in inflammatory-related diseases. Immunopharmacology and Immunotoxicology, 46 (5). pp. 685-694. ISSN 0892-3973; eISSN: 1532-2513 https://www.tandfonline.com/doi/full/10.1080/08923973.2024.2391471 10.1080/08923973.2024.2391471 |
| spellingShingle | Samaila, Abdullahi Basir, Rusliza Gambo Lawal, Mukhtar Abas, Razif Abdullah, Maizaton Atmadini Abd Majid, Roslaini Nordin, Norshariza Hussain, Mohd Khairi Ab Razak, Nur Izah Yoke Keong, Yong Aliyu, Basiru Targeting 8-oxoguanine DNA glycosylase-1 (OGG1) as a therapeutic strategy in inflammatory-related diseases |
| title | Targeting 8-oxoguanine DNA glycosylase-1 (OGG1) as a therapeutic strategy in inflammatory-related diseases |
| title_full | Targeting 8-oxoguanine DNA glycosylase-1 (OGG1) as a therapeutic strategy in inflammatory-related diseases |
| title_fullStr | Targeting 8-oxoguanine DNA glycosylase-1 (OGG1) as a therapeutic strategy in inflammatory-related diseases |
| title_full_unstemmed | Targeting 8-oxoguanine DNA glycosylase-1 (OGG1) as a therapeutic strategy in inflammatory-related diseases |
| title_short | Targeting 8-oxoguanine DNA glycosylase-1 (OGG1) as a therapeutic strategy in inflammatory-related diseases |
| title_sort | targeting 8-oxoguanine dna glycosylase-1 (ogg1) as a therapeutic strategy in inflammatory-related diseases |
| url | http://psasir.upm.edu.my/id/eprint/117856/ http://psasir.upm.edu.my/id/eprint/117856/ http://psasir.upm.edu.my/id/eprint/117856/ http://psasir.upm.edu.my/id/eprint/117856/1/117856.pdf |