Maternal and neonatal group B streptococcus colonisation: A systematic review and the meta-analysis of matched-pair studies
Aim: To determine the prevalence of group B Streptococcus (GBS) carriage among parturient women and neonates, and the relative risk of vertical transmission, the relative risk of early and late-onset GBS and the pooled incidence of early-late-onset GBS infection. Methods: A systematic search of rele...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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John Wiley and Sons Inc
2024
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| Online Access: | http://psasir.upm.edu.my/id/eprint/117808/ http://psasir.upm.edu.my/id/eprint/117808/1/117808.pdf |
| _version_ | 1848867348040122368 |
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| author | Lee, Kai Wei Yap, Sook Fan Murdan, Sudaxshina Zainudin, Zurina Abdul Hamid, Habibah Emamjomeh, Mohsen Mohd Desa, Mohd Nasir Sither Joseph, Narcisse Mary Azmai Amal, Mohammad Noor Amin‐Nordin, Syafinaz |
| author_facet | Lee, Kai Wei Yap, Sook Fan Murdan, Sudaxshina Zainudin, Zurina Abdul Hamid, Habibah Emamjomeh, Mohsen Mohd Desa, Mohd Nasir Sither Joseph, Narcisse Mary Azmai Amal, Mohammad Noor Amin‐Nordin, Syafinaz |
| author_sort | Lee, Kai Wei |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Aim: To determine the prevalence of group B Streptococcus (GBS) carriage among parturient women and neonates, and the relative risk of vertical transmission, the relative risk of early and late-onset GBS and the pooled incidence of early-late-onset GBS infection. Methods: A systematic search of relevant cohort studies from three electronic databases to identify all relevant studies published up to 7 November 2022. The review was conducted in accordance with PRISMA guidelines. Estimates were pooled using random-effects meta-analyses. Results: A total of 54 articles with 355 787 matched pairs of parturient women and neonates from 30 countries were included in the analysis. The pooled prevalence of GBS colonisation was 17.1% among the pregnant women and 1.0% among neonates. The pooled prevalence of vertical transmission of GBS was 4.5% and the pooled relative risk of GBS colonisation of neonates born to mothers with GBS was 9.9. Conclusion: We support the implementation of targeted intrapartum antibiotic prophylaxis for all women who are positive for GBS as well as women with risks factors for early onset GBS in their infants regardless of their GBS colonisation status. |
| first_indexed | 2025-11-15T14:35:04Z |
| format | Article |
| id | upm-117808 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:35:04Z |
| publishDate | 2024 |
| publisher | John Wiley and Sons Inc |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1178082025-06-12T03:29:40Z http://psasir.upm.edu.my/id/eprint/117808/ Maternal and neonatal group B streptococcus colonisation: A systematic review and the meta-analysis of matched-pair studies Lee, Kai Wei Yap, Sook Fan Murdan, Sudaxshina Zainudin, Zurina Abdul Hamid, Habibah Emamjomeh, Mohsen Mohd Desa, Mohd Nasir Sither Joseph, Narcisse Mary Azmai Amal, Mohammad Noor Amin‐Nordin, Syafinaz Aim: To determine the prevalence of group B Streptococcus (GBS) carriage among parturient women and neonates, and the relative risk of vertical transmission, the relative risk of early and late-onset GBS and the pooled incidence of early-late-onset GBS infection. Methods: A systematic search of relevant cohort studies from three electronic databases to identify all relevant studies published up to 7 November 2022. The review was conducted in accordance with PRISMA guidelines. Estimates were pooled using random-effects meta-analyses. Results: A total of 54 articles with 355 787 matched pairs of parturient women and neonates from 30 countries were included in the analysis. The pooled prevalence of GBS colonisation was 17.1% among the pregnant women and 1.0% among neonates. The pooled prevalence of vertical transmission of GBS was 4.5% and the pooled relative risk of GBS colonisation of neonates born to mothers with GBS was 9.9. Conclusion: We support the implementation of targeted intrapartum antibiotic prophylaxis for all women who are positive for GBS as well as women with risks factors for early onset GBS in their infants regardless of their GBS colonisation status. John Wiley and Sons Inc 2024 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/117808/1/117808.pdf Lee, Kai Wei and Yap, Sook Fan and Murdan, Sudaxshina and Zainudin, Zurina and Abdul Hamid, Habibah and Emamjomeh, Mohsen and Mohd Desa, Mohd Nasir and Sither Joseph, Narcisse Mary and Azmai Amal, Mohammad Noor and Amin‐Nordin, Syafinaz (2024) Maternal and neonatal group B streptococcus colonisation: A systematic review and the meta-analysis of matched-pair studies. Acta Paediatrica, International Journal of Paediatrics, 113 (5). pp. 892-911. ISSN 0803-5253; eISSN: 1651-2227 https://onlinelibrary.wiley.com/doi/10.1111/apa.17152 10.1111/apa.17152 |
| spellingShingle | Lee, Kai Wei Yap, Sook Fan Murdan, Sudaxshina Zainudin, Zurina Abdul Hamid, Habibah Emamjomeh, Mohsen Mohd Desa, Mohd Nasir Sither Joseph, Narcisse Mary Azmai Amal, Mohammad Noor Amin‐Nordin, Syafinaz Maternal and neonatal group B streptococcus colonisation: A systematic review and the meta-analysis of matched-pair studies |
| title | Maternal and neonatal group B streptococcus colonisation: A systematic review and the meta-analysis of matched-pair studies |
| title_full | Maternal and neonatal group B streptococcus colonisation: A systematic review and the meta-analysis of matched-pair studies |
| title_fullStr | Maternal and neonatal group B streptococcus colonisation: A systematic review and the meta-analysis of matched-pair studies |
| title_full_unstemmed | Maternal and neonatal group B streptococcus colonisation: A systematic review and the meta-analysis of matched-pair studies |
| title_short | Maternal and neonatal group B streptococcus colonisation: A systematic review and the meta-analysis of matched-pair studies |
| title_sort | maternal and neonatal group b streptococcus colonisation: a systematic review and the meta-analysis of matched-pair studies |
| url | http://psasir.upm.edu.my/id/eprint/117808/ http://psasir.upm.edu.my/id/eprint/117808/ http://psasir.upm.edu.my/id/eprint/117808/ http://psasir.upm.edu.my/id/eprint/117808/1/117808.pdf |