Stability of PRESAGE® dosimeter for end-to-end radiotherapy dosimetry audit and dose delivery

The stability of commercially available PRESAGE® was evaluated for use in complex radiotherapy dose delivery and audit. The dose-response of PRESAGE® under room temperature, low temperature and exposure to visible light was investigated. The photon energy and dose rate dependence of the PRESAGE® wer...

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Main Authors: Mohyedin, Muhammad Zamir, Zin, Hafiz Mohd, Ung, Ngie Min, Bradley, David A., Abdul Rahman, Ahmad Taufek
Format: Article
Language:English
Published: Elsevier Ltd 2025
Online Access:http://psasir.upm.edu.my/id/eprint/117723/
http://psasir.upm.edu.my/id/eprint/117723/1/117723.pdf
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author Mohyedin, Muhammad Zamir
Zin, Hafiz Mohd
Ung, Ngie Min
Bradley, David A.
Abdul Rahman, Ahmad Taufek
author_facet Mohyedin, Muhammad Zamir
Zin, Hafiz Mohd
Ung, Ngie Min
Bradley, David A.
Abdul Rahman, Ahmad Taufek
author_sort Mohyedin, Muhammad Zamir
building UPM Institutional Repository
collection Online Access
description The stability of commercially available PRESAGE® was evaluated for use in complex radiotherapy dose delivery and audit. The dose-response of PRESAGE® under room temperature, low temperature and exposure to visible light was investigated. The photon energy and dose rate dependence of the PRESAGE® were also investigated. It shows a different response under different temperatures. It was demonstrated that this batch of PRESAGE® shows decreased optical density (OD) over time instead of increased OD like a common PRESAGE®. Additionally, the OD of PRESAGE® decreases more slowly which is 0.1 % each hour under low temperature. PRESAGE® also quickly returned to its original state within 48 h post-irradiation under room temperature which the OD decreased by 2.06 % each hour. Upon its return to its original state, the PRESAGE® was able to be reused again with the dose-response reproducibility of more than 99 %. This study also shows that the PRESAGE® is highly sensitive to the visible light radiated by the common fluorescent lamp. The longer the exposure, the higher the optical density within the PRESAGE® which on average, the OD increased by 21.13 % each hour of exposure. The PRESAGE® shows a small dependence of energy with the linearity difference of 5.22 % and shows the independence of dose rate with a variation of less than 5 %.
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spelling upm-1177232025-06-11T01:42:52Z http://psasir.upm.edu.my/id/eprint/117723/ Stability of PRESAGE® dosimeter for end-to-end radiotherapy dosimetry audit and dose delivery Mohyedin, Muhammad Zamir Zin, Hafiz Mohd Ung, Ngie Min Bradley, David A. Abdul Rahman, Ahmad Taufek The stability of commercially available PRESAGE® was evaluated for use in complex radiotherapy dose delivery and audit. The dose-response of PRESAGE® under room temperature, low temperature and exposure to visible light was investigated. The photon energy and dose rate dependence of the PRESAGE® were also investigated. It shows a different response under different temperatures. It was demonstrated that this batch of PRESAGE® shows decreased optical density (OD) over time instead of increased OD like a common PRESAGE®. Additionally, the OD of PRESAGE® decreases more slowly which is 0.1 % each hour under low temperature. PRESAGE® also quickly returned to its original state within 48 h post-irradiation under room temperature which the OD decreased by 2.06 % each hour. Upon its return to its original state, the PRESAGE® was able to be reused again with the dose-response reproducibility of more than 99 %. This study also shows that the PRESAGE® is highly sensitive to the visible light radiated by the common fluorescent lamp. The longer the exposure, the higher the optical density within the PRESAGE® which on average, the OD increased by 21.13 % each hour of exposure. The PRESAGE® shows a small dependence of energy with the linearity difference of 5.22 % and shows the independence of dose rate with a variation of less than 5 %. Elsevier Ltd 2025 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/117723/1/117723.pdf Mohyedin, Muhammad Zamir and Zin, Hafiz Mohd and Ung, Ngie Min and Bradley, David A. and Abdul Rahman, Ahmad Taufek (2025) Stability of PRESAGE® dosimeter for end-to-end radiotherapy dosimetry audit and dose delivery. Radiation Measurements, 184. art. no. 107434. pp. 1-10. ISSN 1350-4487 https://linkinghub.elsevier.com/retrieve/pii/S1350448725000630 10.1016/j.radmeas.2025.107434
spellingShingle Mohyedin, Muhammad Zamir
Zin, Hafiz Mohd
Ung, Ngie Min
Bradley, David A.
Abdul Rahman, Ahmad Taufek
Stability of PRESAGE® dosimeter for end-to-end radiotherapy dosimetry audit and dose delivery
title Stability of PRESAGE® dosimeter for end-to-end radiotherapy dosimetry audit and dose delivery
title_full Stability of PRESAGE® dosimeter for end-to-end radiotherapy dosimetry audit and dose delivery
title_fullStr Stability of PRESAGE® dosimeter for end-to-end radiotherapy dosimetry audit and dose delivery
title_full_unstemmed Stability of PRESAGE® dosimeter for end-to-end radiotherapy dosimetry audit and dose delivery
title_short Stability of PRESAGE® dosimeter for end-to-end radiotherapy dosimetry audit and dose delivery
title_sort stability of presage® dosimeter for end-to-end radiotherapy dosimetry audit and dose delivery
url http://psasir.upm.edu.my/id/eprint/117723/
http://psasir.upm.edu.my/id/eprint/117723/
http://psasir.upm.edu.my/id/eprint/117723/
http://psasir.upm.edu.my/id/eprint/117723/1/117723.pdf