Flavonoids from Clerodendrum genus and their biological activities

Background and purpose: Many studies have been performed to identify new sources, their optimal isolation, and the biological activities of flavonoids due to nutraceutical, pharmaceutical, and cosmeceutical properties. Experimental approach: This review describes the method for flavonoid isolation a...

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Main Authors: Mamuaja, Meiske Naomi, Herlina, Tati, Rumampuk, Rymond Jusuf, Maksum, Iman Permana, Rukayadi, Yaya
Format: Article
Language:English
Published: International Association of Physical Chemists 2024
Online Access:http://psasir.upm.edu.my/id/eprint/117722/
http://psasir.upm.edu.my/id/eprint/117722/1/117722.pdf
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author Mamuaja, Meiske Naomi
Herlina, Tati
Rumampuk, Rymond Jusuf
Maksum, Iman Permana
Rukayadi, Yaya
author_facet Mamuaja, Meiske Naomi
Herlina, Tati
Rumampuk, Rymond Jusuf
Maksum, Iman Permana
Rukayadi, Yaya
author_sort Mamuaja, Meiske Naomi
building UPM Institutional Repository
collection Online Access
description Background and purpose: Many studies have been performed to identify new sources, their optimal isolation, and the biological activities of flavonoids due to nutraceutical, pharmaceutical, and cosmeceutical properties. Experimental approach: This review describes the method for flavonoid isolation and characteristic from the Clerodendrum genus and their biological activities with the indication of the most active ones. To perform a comprehensive review, a thorough literature review using Google Scholar, Scopus, and Science Direct was performed with keyword alone or in combination with other words. Key results: The isolation and identification of flavonoids from the Clerodendrum genus have revealed a variety of compounds using various methods. Various studies conducted in vivo, in vitro and in silico also reported bioactivities of these flavonoids. Conclusion: Several factors determine the flavonoid content in the Clerodendrum genus, among others, the different parts of the plant, extraction techniques, and solvent combination used. Isolated flavonoids also show significant biological activities, such as antioxidant, antiinflammatory, antimicrobials, antidiabetic, anticancer, anti-tyrosinase, and neuroprotective agents.
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spelling upm-1177222025-06-11T01:41:44Z http://psasir.upm.edu.my/id/eprint/117722/ Flavonoids from Clerodendrum genus and their biological activities Mamuaja, Meiske Naomi Herlina, Tati Rumampuk, Rymond Jusuf Maksum, Iman Permana Rukayadi, Yaya Background and purpose: Many studies have been performed to identify new sources, their optimal isolation, and the biological activities of flavonoids due to nutraceutical, pharmaceutical, and cosmeceutical properties. Experimental approach: This review describes the method for flavonoid isolation and characteristic from the Clerodendrum genus and their biological activities with the indication of the most active ones. To perform a comprehensive review, a thorough literature review using Google Scholar, Scopus, and Science Direct was performed with keyword alone or in combination with other words. Key results: The isolation and identification of flavonoids from the Clerodendrum genus have revealed a variety of compounds using various methods. Various studies conducted in vivo, in vitro and in silico also reported bioactivities of these flavonoids. Conclusion: Several factors determine the flavonoid content in the Clerodendrum genus, among others, the different parts of the plant, extraction techniques, and solvent combination used. Isolated flavonoids also show significant biological activities, such as antioxidant, antiinflammatory, antimicrobials, antidiabetic, anticancer, anti-tyrosinase, and neuroprotective agents. International Association of Physical Chemists 2024-12-10 Article PeerReviewed text en cc_by_4 http://psasir.upm.edu.my/id/eprint/117722/1/117722.pdf Mamuaja, Meiske Naomi and Herlina, Tati and Rumampuk, Rymond Jusuf and Maksum, Iman Permana and Rukayadi, Yaya (2024) Flavonoids from Clerodendrum genus and their biological activities. ADMET and DMPK, 12 (6). pp. 843-879. ISSN 1848-7718 https://pub.iapchem.org/ojs/index.php/admet/article/view/2442 10.5599/admet.2442
spellingShingle Mamuaja, Meiske Naomi
Herlina, Tati
Rumampuk, Rymond Jusuf
Maksum, Iman Permana
Rukayadi, Yaya
Flavonoids from Clerodendrum genus and their biological activities
title Flavonoids from Clerodendrum genus and their biological activities
title_full Flavonoids from Clerodendrum genus and their biological activities
title_fullStr Flavonoids from Clerodendrum genus and their biological activities
title_full_unstemmed Flavonoids from Clerodendrum genus and their biological activities
title_short Flavonoids from Clerodendrum genus and their biological activities
title_sort flavonoids from clerodendrum genus and their biological activities
url http://psasir.upm.edu.my/id/eprint/117722/
http://psasir.upm.edu.my/id/eprint/117722/
http://psasir.upm.edu.my/id/eprint/117722/
http://psasir.upm.edu.my/id/eprint/117722/1/117722.pdf