Drug-loaded hydrogel microneedles for sustainable transdermal delivery of macromolecular proteins
Introduction: Poly(methyl vinyl ether co-maleic acid) (PMVE/MA) hydrogel microneedles (HMN) are investigated for transdermal delivery of macromolecular drugs owing to their biocompatibility and super-swelling properties. However, the drug delivery efficacy reduces with increasing molecular weight du...
| Main Authors: | Chandran, Rubhan, Mohd Tohit, Eusni Rahayu, Stanslas, Johnson, Salim, Norazlinaliza, Tuan Mahmood, Tuan Mazlelaa |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Bentham Science Publishers
2025
|
| Subjects: | |
| Online Access: | http://psasir.upm.edu.my/id/eprint/117689/ http://psasir.upm.edu.my/id/eprint/117689/1/117689.pdf |
Similar Items
Investigation and optimisation of hydrogel microneedles for transdermal delivery of caffeine
by: Chandran, Rubhan, et al.
Published: (2022)
by: Chandran, Rubhan, et al.
Published: (2022)
Investigation and optimization of hydrogel microneedles for transdermal delivery of caffeine
by: Chandran, Rubhan, et al.
Published: (2022)
by: Chandran, Rubhan, et al.
Published: (2022)
Recent advances and challenges in microneedle-mediated transdermal
protein and peptide drug delivery
by: Chandran, Rubhan, et al.
Published: (2019)
by: Chandran, Rubhan, et al.
Published: (2019)
Development of halal plant-based hydrocolloids encapsulation for targeted delivery of bovine serum albumin
by: Mohamed, Hajaratul Najwa
Published: (2015)
by: Mohamed, Hajaratul Najwa
Published: (2015)
Characterisation of bovine serum albumin-based biomaterials synthesised by subcritical water technology
by: Esfahan, Zahra Maghareh
Published: (2019)
by: Esfahan, Zahra Maghareh
Published: (2019)
Factors influencing the swelling behaviour of polymethyl vinyl ether-co-maleic acid hydrogels crosslinked by polyethylene glycol
by: Chandran, Rubhan, et al.
Published: (2022)
by: Chandran, Rubhan, et al.
Published: (2022)
Improving rate of gelatin/carboxymethylcellulose dissolving microneedle for transdermal drug delivery
by: Nur Afiqah Mustafa Kamal,, et al.
Published: (2020)
by: Nur Afiqah Mustafa Kamal,, et al.
Published: (2020)
Part A: Outlining the current state of AAVs & evaluating albumins potential role in AAV stability / Part B: Comparing separation resolution of multiple SEC columns & evaluating AAV-albumin interactions
by: Hughes, Oliver
Published: (2024)
by: Hughes, Oliver
Published: (2024)
Purification and characterization of polyclonal anti-hepatitis B core antigen immunoglobulin G from rabbit serum
by: Sayed Hitam, Sharifah Mariam
Published: (2016)
by: Sayed Hitam, Sharifah Mariam
Published: (2016)
Understanding the role of serum albumin on the regulation of drug uptake transporters in the liver
by: Kanwar, Nisha
Published: (2025)
by: Kanwar, Nisha
Published: (2025)
Gradient delivery of bioactive molecules across porous hydrogels
by: Eltaher, Hoda M.M.A.
Published: (2016)
by: Eltaher, Hoda M.M.A.
Published: (2016)
Albumin-drug interaction and its clinical implication
by: Yamasaki, K., et al.
Published: (2013)
by: Yamasaki, K., et al.
Published: (2013)
Preparation of a Monolith with Covalently Bound Bovine Serum Albumin for Capillary Electrochromatography
by: Yao, C., et al.
Published: (2012)
by: Yao, C., et al.
Published: (2012)
Redox properties of serum albumin
by: Anraku, M., et al.
Published: (2013)
by: Anraku, M., et al.
Published: (2013)
Photoaffinity labeling of plasma proteins
by: Chuang, Victor, et al.
Published: (2013)
by: Chuang, Victor, et al.
Published: (2013)
Current trends in polymer microneedle for transdermal drug delivery
by: AL-japairai, Khater Ahmed Saeed, et al.
Published: (2020)
by: AL-japairai, Khater Ahmed Saeed, et al.
Published: (2020)
Stereoselective Binding of Human Serum Albumin
by: Chuang, Victor, et al.
Published: (2006)
by: Chuang, Victor, et al.
Published: (2006)
Dissolving microneedle integrated with benidipine loaded ethosomes for transdermal delivery
by: AL-Japairai, Khater Ahmed Saeed, et al.
Published: (2024)
by: AL-Japairai, Khater Ahmed Saeed, et al.
Published: (2024)
Stress and deformation of optimally shaped silicon microneedles for transdermal drug delivery
by: Zainal Abidin, Hafzaliza Erny, et al.
Published: (2020)
by: Zainal Abidin, Hafzaliza Erny, et al.
Published: (2020)
Biocompatible and mucoadhesive bacterial cellulose-g-poly(acrylic acid) hydrogels for oral protein delivery.
by: Ahmad, N., et al.
Published: (2014)
by: Ahmad, N., et al.
Published: (2014)
Histidine146 of Human Serum Albumin Plays a Prominent Role at the Interface of Subdomains IA and IIA in Allosteric Ligand Binding
by: Kaneko, K., et al.
Published: (2011)
by: Kaneko, K., et al.
Published: (2011)
How Do Fatty Acids Cause Allosteric Binding of Drugs to Human Serum Albumin?
by: Chuang, Victor, et al.
Published: (2002)
by: Chuang, Victor, et al.
Published: (2002)
Flunitrazepam, a 7-nitro-1,4-benzodiazepine that is unable to bind to the indole-benzodiazepine site of human serum albumin
by: Chuang, Victor, et al.
Published: (2001)
by: Chuang, Victor, et al.
Published: (2001)
Transdermal drug delivery system through polymeric microneedle: A recent update
by: Azmana, Motia, et al.
Published: (2020)
by: Azmana, Motia, et al.
Published: (2020)
Non-covalent polymer and drug complexes as targeted delivery system for pulmonary delivery
by: Li, Huitong
Published: (2021)
by: Li, Huitong
Published: (2021)
Shifting paradigms and arising concerns in severe hemophilia A treatment
by: Chandran, Rubhan, et al.
Published: (2024)
by: Chandran, Rubhan, et al.
Published: (2024)
Transdermal insulin on demand
by: Smith, Fiona
Published: (2024)
by: Smith, Fiona
Published: (2024)
Dry-powder formulations of non-covalent protein complexes with linear or miktoarm copolymers for pulmonary delivery
by: Nieto-Orellana, Alejandro, et al.
Published: (2018)
by: Nieto-Orellana, Alejandro, et al.
Published: (2018)
Helix 6 of subdomain III A of human serum albumin is the region primarily photolabeled by ketoprofen, an arylpropionic acid NSAID containing a benzophenone moiety
by: Chuang, Victor, et al.
Published: (1999)
by: Chuang, Victor, et al.
Published: (1999)
Topical and transdermal drug delivery: From simple potions to smart technologies
by: Benson, Heather, et al.
Published: (2019)
by: Benson, Heather, et al.
Published: (2019)
Nanocapsules loaded hydrogels for intra-articular and intra-peritoneal drug delivery
by: Surikutchi, Bhanu Teja
Published: (2020)
by: Surikutchi, Bhanu Teja
Published: (2020)
A polymeric protein-loaded microsphere delivery system for use in bone tissue engineering
by: Boukari, Yamina
Published: (2017)
by: Boukari, Yamina
Published: (2017)
Glargine and degludec: solution behaviour of higher dose synthetic insulins
by: Adams, Gary G., et al.
Published: (2017)
by: Adams, Gary G., et al.
Published: (2017)
Design of poly(HEMA) particles in supercritical carbon dioxide for protein delivery
by: Parilti, Rahmet
Published: (2018)
by: Parilti, Rahmet
Published: (2018)
Cationic supramolecular hydrogels for overcoming the
skin barrier in drug delivery
by: Limon, David, et al.
Published: (2017)
by: Limon, David, et al.
Published: (2017)
Relationship between exposure of airborne pesticides with concentration of pesticide residue in blood serum among farmers in Tanjung Karang, Malaysia
by: Rudzi, Siti Khairunnisaq
Published: (2021)
by: Rudzi, Siti Khairunnisaq
Published: (2021)
Correlating drug release with microstructure of hydrogel-based delivery systems
by: Prasittisart, Pundarik
Published: (2020)
by: Prasittisart, Pundarik
Published: (2020)
Recombinant spider silk protein hydrogels
by: Earlam, Rowan
Published: (2021)
by: Earlam, Rowan
Published: (2021)
Extracellular matrix-derived hydrogels for dental stem cell delivery
by: Viswanath, Aiswarya, et al.
Published: (2016)
by: Viswanath, Aiswarya, et al.
Published: (2016)
Topical Microneedle Drug Delivery Enhanced with Magnetophoresis
by: Prow, T., et al.
Published: (2014)
by: Prow, T., et al.
Published: (2014)
Similar Items
-
Investigation and optimisation of hydrogel microneedles for transdermal delivery of caffeine
by: Chandran, Rubhan, et al.
Published: (2022) -
Investigation and optimization of hydrogel microneedles for transdermal delivery of caffeine
by: Chandran, Rubhan, et al.
Published: (2022) -
Recent advances and challenges in microneedle-mediated transdermal
protein and peptide drug delivery
by: Chandran, Rubhan, et al.
Published: (2019) -
Development of halal plant-based hydrocolloids encapsulation for targeted delivery of bovine serum albumin
by: Mohamed, Hajaratul Najwa
Published: (2015) -
Characterisation of bovine serum albumin-based biomaterials synthesised by subcritical water technology
by: Esfahan, Zahra Maghareh
Published: (2019)