Impact of image enhancement on the radiomics stability of diffusion-weighted MRI images of cervical cancer
The diffusion-weighted imaging (DWI) technique is known for its capability to differentiate the diffusion of water molecules between cancerous and non-cancerous cervix tissues, which enhances the accuracy of detection. Despite the potential of DWI-MRI, its accuracy is limited by technical factors in...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Springer Science and Business Media LLC
2024
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| Online Access: | http://psasir.upm.edu.my/id/eprint/117350/ http://psasir.upm.edu.my/id/eprint/117350/1/117350.pdf |
| _version_ | 1848867225443762176 |
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| author | Ramli, Zarina Farizan, Aishah Tamchek, Nizam Haron, Zaharudin Abdul Karim, Muhammad Khalis |
| author_facet | Ramli, Zarina Farizan, Aishah Tamchek, Nizam Haron, Zaharudin Abdul Karim, Muhammad Khalis |
| author_sort | Ramli, Zarina |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The diffusion-weighted imaging (DWI) technique is known for its capability to differentiate the diffusion of water molecules between cancerous and non-cancerous cervix tissues, which enhances the accuracy of detection. Despite the potential of DWI-MRI, its accuracy is limited by technical factors influencing in vivo data acquisition, thus impacting the quantification of radiomics features. This study aimed to measure the radiomics stability of manual and semi-automated segmentation on contrast limited adaptive histogram equalization (CLAHE)-enhanced DWI-MRI cervical images. Eighty diffusion-weighted MRI images were obtained from patients diagnosed with cervical cancer, and an active contour model was used to analyze the data. Radiomics analysis was conducted to extract the first statistical order, shape, and textural features with intraclass correlation coefficient (ICC) measurement. The results of the CLAHE segmentation approach showed a marked improvement when compared to the manual and semi-automated segmentation methods, with an ICC value of 0.990 ± 0.005 (p<0.05), compared to 0.864 ± 0.033 (p<0.05) and 0.554 ± 0.185 (p>0.05), respectively. The CLAHE segmentation displayed a higher level of robustness than the manual groups in terms of the features present in both categories. Thus, CLAHE segmentation is owing to its potential to generate radiomics features that are more durable and consistent. |
| first_indexed | 2025-11-15T14:33:07Z |
| format | Article |
| id | upm-117350 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T14:33:07Z |
| publishDate | 2024 |
| publisher | Springer Science and Business Media LLC |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1173502025-05-15T00:01:52Z http://psasir.upm.edu.my/id/eprint/117350/ Impact of image enhancement on the radiomics stability of diffusion-weighted MRI images of cervical cancer Ramli, Zarina Farizan, Aishah Tamchek, Nizam Haron, Zaharudin Abdul Karim, Muhammad Khalis The diffusion-weighted imaging (DWI) technique is known for its capability to differentiate the diffusion of water molecules between cancerous and non-cancerous cervix tissues, which enhances the accuracy of detection. Despite the potential of DWI-MRI, its accuracy is limited by technical factors influencing in vivo data acquisition, thus impacting the quantification of radiomics features. This study aimed to measure the radiomics stability of manual and semi-automated segmentation on contrast limited adaptive histogram equalization (CLAHE)-enhanced DWI-MRI cervical images. Eighty diffusion-weighted MRI images were obtained from patients diagnosed with cervical cancer, and an active contour model was used to analyze the data. Radiomics analysis was conducted to extract the first statistical order, shape, and textural features with intraclass correlation coefficient (ICC) measurement. The results of the CLAHE segmentation approach showed a marked improvement when compared to the manual and semi-automated segmentation methods, with an ICC value of 0.990 ± 0.005 (p<0.05), compared to 0.864 ± 0.033 (p<0.05) and 0.554 ± 0.185 (p>0.05), respectively. The CLAHE segmentation displayed a higher level of robustness than the manual groups in terms of the features present in both categories. Thus, CLAHE segmentation is owing to its potential to generate radiomics features that are more durable and consistent. Springer Science and Business Media LLC 2024-11-01 Article PeerReviewed text en cc_by_4 http://psasir.upm.edu.my/id/eprint/117350/1/117350.pdf Ramli, Zarina and Farizan, Aishah and Tamchek, Nizam and Haron, Zaharudin and Abdul Karim, Muhammad Khalis (2024) Impact of image enhancement on the radiomics stability of diffusion-weighted MRI images of cervical cancer. Cureus, 16 (1). art. no. e52132. pp. 1-13. ISSN 2168-8184 https://www.cureus.com/articles/208707-impact-of-image-enhancement-on-the-radiomics-stability-of-diffusion-weighted-mri-images-of-cervical-cancer 10.7759/cureus.52132 |
| spellingShingle | Ramli, Zarina Farizan, Aishah Tamchek, Nizam Haron, Zaharudin Abdul Karim, Muhammad Khalis Impact of image enhancement on the radiomics stability of diffusion-weighted MRI images of cervical cancer |
| title | Impact of image enhancement on the radiomics stability of diffusion-weighted MRI images of cervical cancer |
| title_full | Impact of image enhancement on the radiomics stability of diffusion-weighted MRI images of cervical cancer |
| title_fullStr | Impact of image enhancement on the radiomics stability of diffusion-weighted MRI images of cervical cancer |
| title_full_unstemmed | Impact of image enhancement on the radiomics stability of diffusion-weighted MRI images of cervical cancer |
| title_short | Impact of image enhancement on the radiomics stability of diffusion-weighted MRI images of cervical cancer |
| title_sort | impact of image enhancement on the radiomics stability of diffusion-weighted mri images of cervical cancer |
| url | http://psasir.upm.edu.my/id/eprint/117350/ http://psasir.upm.edu.my/id/eprint/117350/ http://psasir.upm.edu.my/id/eprint/117350/ http://psasir.upm.edu.my/id/eprint/117350/1/117350.pdf |