Mycobacterium senegalense catheter-related bloodstream infection
Catheter-related bloodstream infection (CRBSI) is one of the common healthcare-acquired infections imposing a high burden of morbidity and mortality on the patients. Non-tuberculous mycobacterium is a rare aetiology for CRBSI and poses challenges in laboratory diagnosis and clinical management. This...
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| Format: | Article |
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BMJ Publishing Group
2024
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| Online Access: | http://psasir.upm.edu.my/id/eprint/117324/ |
| _version_ | 1848867217952735232 |
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| author | Amin Nordin, Syafinaz Badarol Hisham, Noralwani Masri, Siti Norbaya Madon, Mazriza |
| author_facet | Amin Nordin, Syafinaz Badarol Hisham, Noralwani Masri, Siti Norbaya Madon, Mazriza |
| author_sort | Amin Nordin, Syafinaz |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Catheter-related bloodstream infection (CRBSI) is one of the common healthcare-acquired infections imposing a high burden of morbidity and mortality on the patients. Non-tuberculous mycobacterium is a rare aetiology for CRBSI and poses challenges in laboratory diagnosis and clinical management. This is a case of a woman in her early 60s with underlying end-stage renal failure, diabetes mellitus and hypertension presented with a 2-week history of high-grade fever postregular haemodialysis, vomiting, lethargy and altered mental status. Blood cultures from a permanent catheter and peripheral taken concurrently yielded Mycobacterium senegalense, identified by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry, which established the diagnosis of CRBSI atypically presented with concurrent acute intracranial bleeding and cerebrovascular infarction at initial presentation. She was started on a combination of oral azithromycin, oral amikacin and intravenous imipenem, and the permanent catheter was removed. Despite the treatments instituted, she developed septicaemia, acute myocardial infarction and macrophage activation-like syndrome, causing the patient’s death. |
| first_indexed | 2025-11-15T14:33:00Z |
| format | Article |
| id | upm-117324 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-15T14:33:00Z |
| publishDate | 2024 |
| publisher | BMJ Publishing Group |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-1173242025-05-14T06:13:05Z http://psasir.upm.edu.my/id/eprint/117324/ Mycobacterium senegalense catheter-related bloodstream infection Amin Nordin, Syafinaz Badarol Hisham, Noralwani Masri, Siti Norbaya Madon, Mazriza Catheter-related bloodstream infection (CRBSI) is one of the common healthcare-acquired infections imposing a high burden of morbidity and mortality on the patients. Non-tuberculous mycobacterium is a rare aetiology for CRBSI and poses challenges in laboratory diagnosis and clinical management. This is a case of a woman in her early 60s with underlying end-stage renal failure, diabetes mellitus and hypertension presented with a 2-week history of high-grade fever postregular haemodialysis, vomiting, lethargy and altered mental status. Blood cultures from a permanent catheter and peripheral taken concurrently yielded Mycobacterium senegalense, identified by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry, which established the diagnosis of CRBSI atypically presented with concurrent acute intracranial bleeding and cerebrovascular infarction at initial presentation. She was started on a combination of oral azithromycin, oral amikacin and intravenous imipenem, and the permanent catheter was removed. Despite the treatments instituted, she developed septicaemia, acute myocardial infarction and macrophage activation-like syndrome, causing the patient’s death. BMJ Publishing Group 2024 Article PeerReviewed Amin Nordin, Syafinaz and Badarol Hisham, Noralwani and Masri, Siti Norbaya and Madon, Mazriza (2024) Mycobacterium senegalense catheter-related bloodstream infection. BMJ Case Reports, 17 (4). art. no. e259761. ISSN 1757-790X https://casereports.bmj.com/content/17/4/e259761 |
| spellingShingle | Amin Nordin, Syafinaz Badarol Hisham, Noralwani Masri, Siti Norbaya Madon, Mazriza Mycobacterium senegalense catheter-related bloodstream infection |
| title | Mycobacterium senegalense catheter-related bloodstream infection |
| title_full | Mycobacterium senegalense catheter-related bloodstream infection |
| title_fullStr | Mycobacterium senegalense catheter-related bloodstream infection |
| title_full_unstemmed | Mycobacterium senegalense catheter-related bloodstream infection |
| title_short | Mycobacterium senegalense catheter-related bloodstream infection |
| title_sort | mycobacterium senegalense catheter-related bloodstream infection |
| url | http://psasir.upm.edu.my/id/eprint/117324/ http://psasir.upm.edu.my/id/eprint/117324/ |