5-fluorouracil in combination with calcium carbonate nanoparticles loaded with antioxidant thymoquinone against colon cancer: synergistically therapeutic potential and underlying molecular mechanism

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5-fluorouracil in combination with calcium carbonate nanoparticles loaded with antioxidant thymoquinone against colon cancer: synergistically therapeutic potential and underlying molecular mechanism

Colon cancer is the third most common cancer worldwide, with high mortality. Adverse side effects and chemoresistance of the first-line chemotherapy 5-fluorouracil (5-FU) have promoted the widespread use of combination therapies. Thymoquinone (TQ) is a natural compound with potent antioxidant activi...

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Bibliographic Details
Main Authors:	Deng, Xi, Yang, Zhongming, Chan, Kim Wei, Ismail, Norsharina, Abu Bakar, Md Zuki
Format:	Article
Language:	English
Published:	Multidisciplinary Digital Publishing Institute 2024
Online Access:	http://psasir.upm.edu.my/id/eprint/117226/ http://psasir.upm.edu.my/id/eprint/117226/1/117226.pdf

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