Different concentrations of nivolumab reduce PD-1 expression but not tumour growth in an EMT6 mouse model

Different concentrations of nivolumab reduce PD-1 expression but not tumour growth in an EMT6 mouse model

Introduction: The interaction between the T cell immune checkpoint proteins, the programmed death-1 (PD-1) receptor, and its ligand PD-L1 plays a crucial role in T cell suppression and the evasion of cancer cells from immune detection, thereby promoting tumour growth. Nivolumab, a PD-1 inhibitor, di...

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Main Authors: Ronny Sham, Nur Fatihah, Husainy Hasbullah, Harissa, Abdul Hamid Hasani, Narimah, Hasan, Nurhaslina, Othman, Suraya, Osman, Nora Julianna, Abdul Karim, Muhammad Khalis, Syed Ahmad Fuad, Syed Baharom, Ibahim, Mohammad Johari
Format: Article
Language:English
Published: BiomedPress 2024
Online Access:http://psasir.upm.edu.my/id/eprint/117086/
http://psasir.upm.edu.my/id/eprint/117086/1/117086.crdownload

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